Gene

KWMTBOMO00340  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA000701

Annotation

catalase_[Bombyx_mori]

Location

Bomo_Chr1(+):10353389-10355814      View in EpiBrowser

Full name

Catalase      

Location in the cell

Peroxisomal   Reliability : 3.293

CDS

ATGGCTTCAAGAGACCCAGCTACTGACCAACTCATTAACTACAAGAAAACTTTAAAGGATTCTCCTGGTTTCATCACCACTAAATCTGGAGCTCCTGTTGGAATCAAAACGGCGATACAAACGGTGGGCAAGAATGGTCCAGCCTTATTACAGGATGTTAACTTTCTTGATGAAATGTCATCCTTTGACAGGGAGCGTATTCCAGAACGAGTGGTACATGCTAAAGGAGCTGGAGCTTTTGGGTACTTTGAAGTAACTCATGACATCACCAAGTACAGTGCTGCCAAAGTATTTGAGTCCATAGGCAAAAGGACACCGATTGCTGTTAGATTCTCAACAGTTGGTGGAGAGAGTGGATCTGCTGATACTGTTCGTGACCCTCGAGGTTTTGCTGTAAAGTTCTATACTGATGATGGAGTGTGGGATTTAGTTGGAAATAATACTCCCATTTTCTTTATAAGAGATCCAACATTATTCCCGAGTTTTATCCATACTCAGAAGAGAAACCCTGCAACACATCTGAAAGATCCAGACATGTTTTGGGACTTTTTGACCTTAAGACCAGAGACCATCCATCAACTTCTTTACTTGTTTGGAGACCGTGGTATTCCTGATGGCTACAGACATATGAATGGATATGGTTCCCATACATTCAAGCTTGTGAATTCTCAAGGTGTTGGGTACTGGGTAAAATTCCACTATAAGACTAACCAGGGGATTAAAAACTTATCAGTTGACAAAGCAGGTGAACTGGCATCAACTGATCCTGATTATTCCATTAGAGATCTGTATAATTCCATTGCAAAGGGTGATTACCCATCATGGACTTTTTACATTCAGGTGATGACTATGGCTCAAGCAGAAAGCTGTAAATTTAATCCGTTTGACCTAACTAAGATCTGGCCACATGCAGAATATCCTTTAATTCCTGTTGGTAAATTGGTTTTGGATAGAAACCCTAAGAATTACTTTGCTGAAGTTGAACAAATTGCTTTCAGTCCATCTAATTTAGTACCAGGAATTGAGCCATCTCCAGACAAAATGTTACAAGGAAGACTGTTTGCCTATAGCGATACACATCGCCATAGACTTGGTGCTAACTACCTCCAAATTCCTGTAAATTGTCCATACAAAGTTGCTGTTTCCACCTACCAGCGTGATGGACCTCAAGCTATTCACAATCAAGACGACTGCCCTAACTATTTCCCCAACTCTTTTTCTGGACCACAAGAATGTCCACGTGCTCAGCGTTTGCAACCTCGATACAATGTCGGCGGAGATGTAGACCGGTATGATAGTGGCCAGACTGAGGACAACTTCTCCCAAGCGACAGCACTGTATAAACAAGTTTTTGATGATGCAGCTAAACAACGAGCTATTGCCAATATAGTAGATCACCTCAAGGATGCTGCTGCGTTTATTCAAGAAAGAGCTATCAAGATCTTCTCTCAGGTACATCCTGAACTTGGAAATAAAGTAGCAGCTGGTTTAGCTCCTTACAAAAAATATCATGCAAATTTGTAA

Protein

MASRDPATDQLINYKKTLKDSPGFITTKSGAPVGIKTAIQTVGKNGPALLQDVNFLDEMSSFDRERIPERVVHAKGAGAFGYFEVTHDITKYSAAKVFESIGKRTPIAVRFSTVGGESGSADTVRDPRGFAVKFYTDDGVWDLVGNNTPIFFIRDPTLFPSFIHTQKRNPATHLKDPDMFWDFLTLRPETIHQLLYLFGDRGIPDGYRHMNGYGSHTFKLVNSQGVGYWVKFHYKTNQGIKNLSVDKAGELASTDPDYSIRDLYNSIAKGDYPSWTFYIQVMTMAQAESCKFNPFDLTKIWPHAEYPLIPVGKLVLDRNPKNYFAEVEQIAFSPSNLVPGIEPSPDKMLQGRLFAYSDTHRHRLGANYLQIPVNCPYKVAVSTYQRDGPQAIHNQDDCPNYFPNSFSGPQECPRAQRLQPRYNVGGDVDRYDSGQTEDNFSQATALYKQVFDDAAKQRAIANIVDHLKDAAAFIQERAIKIFSQVHPELGNKVAAGLAPYKKYHANL

Description

Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.

Catalytic Activity

2 H2O2 = 2 H2O + O2

Cofactor

heme

Subunit

Homotetramer.

Similarity

Belongs to the catalase family.

Keywords

Complete proteome   Direct protein sequencing   Heme   Hydrogen peroxide   Iron   Metal-binding   Oxidoreductase   Peroxidase   Peroxisome   Reference proteome  

Feature

chain  Catalase

Uniprot

H9ITX1   Q68AP5   A0A194QVH0   A0A1V0QH47   A0A194PRI4   A0A2R2PTF8   + More
H9BEW3   G5CDD8   I4DMH7   A0A2H1WQ68   A0A286RZM9   A0A2Z4N440   H9U5T8   S4PA78   A0A212F436   A0A0L7KXM9   A0A2S0RQP9   A0A0L7KZY0   F4MI31   A0A1B0CRV7   A0A1I8PLT9   A8CWF1   A0A3B0JYK5   A0A0L0C8Y9   A0A0K8TMT3   A0A1I8MF15   B4PIY6   A0A1I8PLM9   B4QPW5   T1PCG9   B4IFV9   B3NHN7   A0A1L8EEQ5   B4KXS2   Q2M0D6   A0A0N9E6Y9   A0A1L8EEC3   A0A034WTI4   A0A0C9Q530   B4N4F5   A0A0M4EK05   B3M869   A0A336N5N6   A0A0A1WYM5   P17336   A0A1W4UPD3   B4J1T4   W8C3S7   A0A0K8VAH0   T1E775   J9HGP0   A0A1L7LQD2   A0A182FDJ3   A0A023EUF0   Q16J86   A0A2M4BKY1   A0A1L8E475   A0A182GFN9   G9BQS7   A0A087ZC72   A0A2M4A193   A0A084WKX1   A0A1L8E4H4   K4N1L2   B4LFX2   A0A182IJJ1   E0YL15   A0A2M3YYC6   A0A2M3ZFP9   A0A2M4A1E0   A0A2M4CPT1   A0A2J7REJ5   A0A2M3YYJ7   A0A182WS20   A3E807   A0A182HQG6   A0A182UXY3   A0A1J1I836   A0A2M4CV05   A3E7Z8   A0A2M4CTV7   A0A182LDW5   A0A182PEB9   A3E800   A0A182QZS4   E2AJX6   A0A1B3PEJ4   A0A2M4A121   W5JER1   A0A067RLP1   A0A2M4A0F7   A0A1Q3FPN2   A0A131XJ28   G9C5E5   A0A224YPR9   A0A182N228   A0A224YJA5   A0A224YJ98   L7M7X5   A0A2U8T6B2  

EC Number

1.11.1.6

Pubmed

19121390    15763464    26354079    22651552    23622113    22118469    + More
26227816    21569254    18194529    26108605    26369729    25315136    17994087    17550304    22936249    15632085    25348373    25830018    8660653    2362827    10731132    12537572    12537569    8500545    24495485    17510324    26760975    28076409    24945155    26483478    23441231    20920257    24438588    21103355    17284604    12364791    14747013    17210077    20966253    20798317    27521923    24845553    28049606    21835214    28797301    25576852   

EMBL

BABH01007112    AB164195    BAD38853.1    KQ461108    KPJ09319.1    KY701971    + More
ARE67828.1    KQ459594    KPI96061.1    KX079633    KX065288    ANA84065.1    JQ009332    AFC98367.1    JN051294    AEP40969.1    AK402495    BAM19117.1    ODYU01010180    SOQ55126.1    MF737386    ASX95436.1    MG397135    AWX63639.1    JQ663444    AFG31725.1    GAIX01003369    JAA89191.1    AGBW02010446    OWR48497.1    JTDY01004753    KOB67801.1    MF979105    AWA45968.1    JTDY01004115    KOB68584.1    EZ617712    ADH94605.1    AJWK01025349    AJWK01025350    AJWK01025351    AJWK01025352    EU124624    ABV60342.1    OUUW01000002    SPP76188.1    JRES01000836    KNC27864.1    GDAI01002147    JAI15456.1    CM000159    EDW94577.1    CM000363    CM002912    EDX10993.1    KMZ00447.1    KA645638    AFP60267.1    CH480834    EDW46546.1    CH954178    EDV51832.1    GFDG01001766    JAV17033.1    CH933809    EDW19779.1    CH379069    EAL30998.1    KR072552    ALF39394.1    GFDG01001805    JAV16994.1    GAKP01001864    JAC57088.1    GBYB01009173    JAG78940.1    CH964095    EDW79029.1    CP012525    ALC44426.1    CH902618    EDV41008.1    UFQT01002634    SSX33828.1    GBXI01010123    JAD04169.1    U00145    X52286    AE014296    AY084154    CH916366    EDV98014.1    GAMC01002637    JAC03919.1    GDHF01016433    JAI35881.1    GAMD01003292    JAA98298.1    CH478024    EJY58037.1    FX983163    BAV93783.1    GAPW01001047    JAC12551.1    EAT34333.1    GGFJ01004541    MBW53682.1    GFDF01000551    JAV13533.1    JXUM01010672    JXUM01010673    KQ560314    KXJ83094.1    HQ659100    AET14833.1    GGFK01001087    MBW34408.1    ATLV01024156    KE525350    KFB50865.1    GFDF01000550    JAV13534.1    JX513905    AFV36369.1    CH940647    EDW70371.1    HM062769    ADM26625.1    GGFM01000531    MBW21282.1    GGFM01006499    MBW27250.1    GGFK01001248    MBW34569.1    GGFL01003168    MBW67346.1    NEVH01004961    PNF39255.1    GGFM01000570    MBW21321.1    DQ980208    DQ980209    ABL09376.1    APCN01004603    CVRI01000043    CRK95906.1    GGFL01004500    MBW68678.1    DQ980199    DQ980200    DQ980204    DQ980205    DQ980206    DQ980207    AAAB01008948    ABL09367.1    ABL09372.1    EAA10427.4    GGFL01004531    MBW68709.1    DQ986315    DQ980201    DQ980202    DQ980203    DQ980210    ABK59975.1    ABL09369.1    AXCN02002351    GL440100    EFN66292.1    KT716445    AOG21082.1    GGFK01001195    MBW34516.1    ADMH02001698    ETN61375.1    KK852549    KDR21530.1    GGFK01000918    MBW34239.1    GFDL01005612    JAV29433.1    GEFH01002463    JAP66118.1    HQ851386    AEV89764.1    GFPF01006583    MAA17729.1    GFPF01006581    MAA17727.1    GFPF01006582    MAA17728.1    GACK01004914    JAA60120.1    KY953208    AWM72026.1   

Proteomes

UP000005204    UP000053240    UP000053268    UP000007151    UP000037510    UP000092461    + More
UP000095300    UP000268350    UP000037069    UP000095301    UP000002282    UP000000304    UP000001292    UP000008711    UP000009192    UP000001819    UP000007798    UP000092553    UP000007801    UP000000803    UP000192221    UP000001070    UP000008820    UP000069272    UP000069940    UP000249989    UP000030765    UP000008792    UP000075880    UP000235965    UP000076407    UP000075840    UP000075903    UP000183832    UP000007062    UP000075882    UP000075885    UP000075886    UP000000311    UP000000673    UP000027135    UP000075884   

PRIDE

H9ITX1    Q68AP5    P17336    L7M7X5   

Pfam

PF00199   Catalase        + More
PF06628   Catalase-rel

Interpro

IPR020835   Catalase_sf        + More
IPR011614   Catalase_core       
IPR024711   Catalase_clade1/3       
IPR002226   Catalase_haem_BS       
IPR024708   Catalase_AS       
IPR018028   Catalase       
IPR010582   Catalase_immune_responsive       
IPR040333   Catalase_3       
IPR037060   Catalase_core_sf       
IPR019786   Zinc_finger_PHD-type_CS       
IPR019787   Znf_PHD-finger       
IPR013083   Znf_RING/FYVE/PHD       
IPR001965   Znf_PHD       
IPR011011   Znf_FYVE_PHD       
IPR010916   TonB_box_CS       

SUPFAM

SSF56634   SSF56634        + More
SSF57903   SSF57903       

Gene 3D

2.40.180.10     3.30.40.10    

CDD

cd08156  catalase_clade_3

ProteinModelPortal

H9ITX1   Q68AP5   A0A194QVH0   A0A1V0QH47   A0A194PRI4   A0A2R2PTF8   + More
H9BEW3   G5CDD8   I4DMH7   A0A2H1WQ68   A0A286RZM9   A0A2Z4N440   H9U5T8   S4PA78   A0A212F436   A0A0L7KXM9   A0A2S0RQP9   A0A0L7KZY0   F4MI31   A0A1B0CRV7   A0A1I8PLT9   A8CWF1   A0A3B0JYK5   A0A0L0C8Y9   A0A0K8TMT3   A0A1I8MF15   B4PIY6   A0A1I8PLM9   B4QPW5   T1PCG9   B4IFV9   B3NHN7   A0A1L8EEQ5   B4KXS2   Q2M0D6   A0A0N9E6Y9   A0A1L8EEC3   A0A034WTI4   A0A0C9Q530   B4N4F5   A0A0M4EK05   B3M869   A0A336N5N6   A0A0A1WYM5   P17336   A0A1W4UPD3   B4J1T4   W8C3S7   A0A0K8VAH0   T1E775   J9HGP0   A0A1L7LQD2   A0A182FDJ3   A0A023EUF0   Q16J86   A0A2M4BKY1   A0A1L8E475   A0A182GFN9   G9BQS7   A0A087ZC72   A0A2M4A193   A0A084WKX1   A0A1L8E4H4   K4N1L2   B4LFX2   A0A182IJJ1   E0YL15   A0A2M3YYC6   A0A2M3ZFP9   A0A2M4A1E0   A0A2M4CPT1   A0A2J7REJ5   A0A2M3YYJ7   A0A182WS20   A3E807   A0A182HQG6   A0A182UXY3   A0A1J1I836   A0A2M4CV05   A3E7Z8   A0A2M4CTV7   A0A182LDW5   A0A182PEB9   A3E800   A0A182QZS4   E2AJX6   A0A1B3PEJ4   A0A2M4A121   W5JER1   A0A067RLP1   A0A2M4A0F7   A0A1Q3FPN2   A0A131XJ28   G9C5E5   A0A224YPR9   A0A182N228   A0A224YJA5   A0A224YJ98   L7M7X5   A0A2U8T6B2  

PDB

6JNU     E-value=0,     Score=1803

KEGG

692456    K03781 catalase [EC:1.11.1.6] | (RefSeq) Cat; catalase

PATHWAY

00380    Tryptophan metabolism - Bombyx mori (domestic silkworm)
00630    Glyoxylate and dicarboxylate metabolism - Bombyx mori (domestic silkworm)
01100    Metabolic pathways - Bombyx mori (domestic silkworm)
01200    Carbon metabolism - Bombyx mori (domestic silkworm)
04068    FoxO signaling pathway - Bombyx mori (domestic silkworm)
04146    Peroxisome - Bombyx mori (domestic silkworm)
04213    Longevity regulating pathway - multiple species - Bombyx mori (domestic silkworm)

GO

GO:0042744   GO:0006979   GO:0004096   GO:0020037   GO:0046872   GO:0003007   GO:0042542   GO:0035206   GO:0034976   GO:0048167   GO:0038001   GO:0036335   GO:0072593   GO:0008340   GO:0005777   GO:0007568   GO:0016209   GO:0007018   GO:0030286   GO:0006813   GO:0006810   GO:0009072   GO:0007169   GO:0016021   GO:0055114  

PANTHER

PTHR11465  

Subcellular location

Peroxisome  

Length:

507

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.0247499999999999

Exp number, first 60 AAs:

0.02249

Total prob of N-in:

0.00654

outside

1  -  507

 

 

Pi

1.380674

Theta

2.20691

Tajima's D

-0.997825

CLR

0.007998

CSRT

0.134243287835608

Interpretation

Possibly Positive selection