Gene

KWMTBOMO00333  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA000529

Annotation

PREDICTED:_neutral_endopeptidase_24.11_isoform_X2_[Bombyx_mori]

Location

Bomo_Chr1(-):10085385-10117748      View in EpiBrowser

Location in the cell

PlasmaMembrane   Reliability : 1.104

CDS

ATGAGAAACAACGTAAAGCAATCGTTCTGGCGACCTCGCACTGACGCTGAGAAACGATGGATGATGATAGCTGGAGTGGCCGCAGTGCTCGCCGTCGCGTTCTTGGCAGCCTTCATCGCCAGCCTTCTCCTACGAACAACCAGCGACATAAGCGTGGTCGCCCGGGGATCAGATGACGTGGAAACGTGTAGCGCACCTGGGTGTATCCATACAGCCTCAAGACTCCTGCTGAATATGGATGAAAAAGTAGACCCATGCGACAATTTCTACGACTTTGCTTGCGGGTCATTCTTGAAAAATACTAGGATCCCAGACGACAAGACCTCAGTGAACACGTTTTCAATTATCACTGATCAACTCCAAGAGCAGATTCGGTCACTTTTAGACGAACCAGTCACTCCTGAAGAGCCGAGACCATTCGTGCTCGCCAAAACCTTGTACCAAGCTTGCATGAACAGAACTGCCATTGAAGCTCGAGGTGTCCAACCATTGCTGGATATGCTGAAACGGCTCGGAGGTTGGCCTGTACTTGATGGTCAGTCATGGGACGAGAACTCATTTTCTTGGGAGCAATCGGTGTACAAATTCAGAGATGCCGGTTACTCCGTCGATTACTTCCTCGATTTCTCTATCAGCGTGGATGTTAAAAATTCAACGAGACGAGTCATTGATCTGGACCAGGCCTCGCTCGGATTAAGCCGCGAGTACCTGAACCGCGGCTTCAGTGATAAATTGGTACAAGCATACTATGAGTACATGGTCGATATCGCTATACTCCTTGGAGCTGATAAGACAAAGGCTACAGAAGAACTTAAAGAATCACTGCAATTCGAAATGAAATTAGCCAACATTTCGTTACCTCTGGAAAAACGTCGTAACGCAACGAGTCTCTACAACCCTATGACCATTGCTGAACTTCAACAGAAATTCCCCAAGGTTCCGTGGTTGGAATACATCAACAGACTGCTTGCGCCACACATTACGGTCGATGTTAATGAACTTACCATTGTCAGCGTACCCAAATACATCACCGATCTTGAGGCTTTACTGGAGAAGACTCCTAAACGTGTACAAGCTAACTACGTCATGTGGAGAGTTGCCGGGGCATCAGTTTCGTACCTAACTGACGATCTGAGGAGACGACAATTGGCCTACATCACAGCTTTGTCAGGAAAAACTGAACGCGAGAGTAGATGGAAAGAATGCGCCGATACGACCAGTGCTAGCATGTCCATCGCTGTAGGGGCGCTGTACATCAGGAAATATTTCAATGAAAACTCAAAGGCGAATGCTTTAGAAATGGTCAATGATATCAGGTAA

Protein

MRNNVKQSFWRPRTDAEKRWMMIAGVAAVLAVAFLAAFIASLLLRTTSDISVVARGSDDVETCSAPGCIHTASRLLLNMDEKVDPCDNFYDFACGSFLKNTRIPDDKTSVNTFSIITDQLQEQIRSLLDEPVTPEEPRPFVLAKTLYQACMNRTAIEARGVQPLLDMLKRLGGWPVLDGQSWDENSFSWEQSVYKFRDAGYSVDYFLDFSISVDVKNSTRRVIDLDQASLGLSREYLNRGFSDKLVQAYYEYMVDIAILLGADKTKATEELKESLQFEMKLANISLPLEKRRNATSLYNPMTIAELQQKFPKVPWLEYINRLLAPHITVDVNELTIVSVPKYITDLEALLEKTPKRVQANYVMWRVAGASVSYLTDDLRRRQLAYITALSGKTERESRWKECADTTSASMSIAVGALYIRKYFNENSKANALEMVNDIR

Uniprot

Q9BLH1   H9ITE9   A0A2A4JWQ5   A0A2A4JX35   Q86RS4   A0A2U8JG00   + More
A0A2H1W5X7   A0A437B0E3   A0A1E1W8K7   A0A212F433   S4NTA7   A0A194QVE0   A0A194PTK8   A0A0L7R038   A0A139WI73   A0A139WHP0   A0A0C9RKX4   A0A0C9S0X3   A0A088AKD7   A0A0M9A0V4   K7J3Q5   N6UII9   A0A172QPK9   A0A026W1C7   A0A3L8DWD5   E0W1I2   A0A2S1TP67   E2AFA5   A0A2A3EL10   A0A154P8A9   U4U6M7   A0A1W4W608   A0A1W4WHQ7   A0A1W4W5Z7   E9IRU9   A0A1Y1K718   A0A1Y1K6C4   A0A2J7RR19   A0A1Y1K3H5   A0A1Y1K673   A0A3Q0J997   A0A232F7R6   A0A151J2K9   A0A067RF34   A0A151I329   A0A0T6BF71   A0A1I9WLF9   A0A158NUJ2   A0A2P8ZBL6   A0A0U3KDJ5   F4WRD2   A0A195C7U5   A0A2H8TNG1   A0A195FJU4   A0A2S2R687   J9JK87   A0A2S2QFC1   E2C244   A0A1Q3G120   A0A0K8TLN7   A0A182Q5Q1   A0A1S4GDN6   A0A340TB26   A0A182HGU4   Q7PY82   A0A182U1K2   A0A1S4FNM5   A0A182X2S6   A0A182VC38   A0A1Q3G159   A0A2M4CV03   A0A182J9J9   Q16UJ2   A0A0J7NSM8   A0A182NFL8   A0A1Q3G115   A0A182KMD2   A0A1L8E2J5   A0A182F8P8   A0A182JR91   A0A182LWV4   A0A1L8E2C7   A0A182VRK4   A0A1L8E257   A0A226EKZ6   A0A084VWM9   A0A182G3C1   Q8T660   A0A182P9R2   A0A1D2MVE1   A0A182XV77   A0A182T699   A0A336MVN8   A0A1B6CAF7   A0A1B6DD22   U5EU91   A0A182RNY2   W5JAQ0   A0A1B0CSU2   A0A023EVJ3  

Pubmed

11583934    19121390    22118469    23622113    26354079    18362917    + More
19820115    20075255    23537049    24508170    30249741    20566863    29727440    20798317    21282665    28004739    28648823    24845553    27538518    21347285    29403074    26694822    21719571    26369729    12364791    17510324    20966253    24438588    26483478    12230546    27289101    25244985    20920257    23761445    24945155   

EMBL

AB048208    BAB33300.1    BABH01007095    BABH01007096    NWSH01000486    PCG76064.1    + More
PCG76063.1    AF413063    AAO21504.1    MH298329    AWK67618.1    ODYU01006558    SOQ48505.1    RSAL01000227    RVE43942.1    GDQN01007734    JAT83320.1    AGBW02010446    OWR48508.1    GAIX01012266    JAA80294.1    KQ461108    KPJ09289.1    KQ459594    KPI96089.1    KQ414672    KOC64187.1    KQ971343    KYB27447.1    KYB27446.1    GBYB01007566    JAG77333.1    GBYB01014266    JAG84033.1    KQ435774    KOX75065.1    APGK01034174    APGK01034175    APGK01034176    APGK01034177    APGK01034178    KB740904    ENN78462.1    KU245762    AND99761.1    KK107496    EZA49818.1    QOIP01000004    RLU24088.1    DS235870    EEB19488.1    MF189027    AWI63381.1    GL439090    EFN67881.1    KZ288217    PBC32410.1    KQ434824    KZC07350.1    KB632006    ERL87973.1    GL765283    EFZ16711.1    GEZM01094022    JAV56000.1    GEZM01094024    JAV55998.1    NEVH01000611    PNF43276.1    GEZM01094023    JAV55999.1    GEZM01094021    JAV56001.1    NNAY01000760    OXU26642.1    KQ980368    KYN16324.1    KK852675    KDR18716.1    KQ976533    KYM81493.1    LJIG01001105    KRT85835.1    KU932343    APA33979.1    ADTU01026577    ADTU01026578    ADTU01026579    ADTU01026580    ADTU01026581    PYGN01000114    PSN53889.1    KU218675    ALX00055.1    GL888285    EGI63203.1    KQ978143    KYM96720.1    GFXV01003870    MBW15675.1    KQ981522    KYN40631.1    GGMS01016230    MBY85433.1    ABLF02019556    GGMS01006699    MBY75902.1    GL452067    EFN77995.1    GFDL01001550    JAV33495.1    GDAI01002525    JAI15078.1    AXCN02000208    AAAB01008987    APCN01005946    EAA01126.5    GFDL01001511    JAV33534.1    GGFL01004490    MBW68668.1    CH477621    EAT38188.1    LBMM01001992    KMQ95435.1    GFDL01001557    JAV33488.1    GFDF01001146    JAV12938.1    AXCM01000914    GFDF01001260    JAV12824.1    GFDF01001261    JAV12823.1    LNIX01000003    OXA57411.1    ATLV01017670    KE525181    KFB42373.1    JXUM01040714    JXUM01040715    JXUM01040716    JXUM01040717    JXUM01040718    JXUM01040719    JXUM01040720    AF483275    AAL91975.1    LJIJ01000490    ODM96912.1    UFQS01003165    UFQT01003165    SSX15299.1    SSX34674.1    GEDC01026857    JAS10441.1    GEDC01013803    JAS23495.1    GANO01002427    JAB57444.1    ADMH02001926    ETN60478.1    AJWK01026604    AJWK01026605    AJWK01026606    GAPW01000552    JAC13046.1   

Proteomes

UP000005204    UP000218220    UP000283053    UP000007151    UP000053240    UP000053268    + More
UP000053825    UP000007266    UP000005203    UP000053105    UP000002358    UP000019118    UP000053097    UP000279307    UP000009046    UP000000311    UP000242457    UP000076502    UP000030742    UP000192223    UP000235965    UP000079169    UP000215335    UP000078492    UP000027135    UP000078540    UP000005205    UP000245037    UP000007755    UP000078542    UP000078541    UP000007819    UP000008237    UP000075886    UP000075903    UP000075840    UP000007062    UP000075902    UP000076407    UP000075880    UP000008820    UP000036403    UP000075884    UP000075882    UP000069272    UP000075881    UP000075883    UP000075920    UP000198287    UP000030765    UP000069940    UP000075885    UP000094527    UP000076408    UP000075901    UP000075900    UP000000673    UP000092461   

PRIDE

Q9BLH1    H9ITE9   

Pfam

PF01431   Peptidase_M13        + More
PF05649   Peptidase_M13_N
PF08324   PUL
PF09070   PFU
PF00400   WD40
PF02020   W2
PF01873   eIF-5_eIF-2B

Interpro

IPR024079   MetalloPept_cat_dom_sf        + More
IPR008753   Peptidase_M13_N       
IPR042089   Peptidase_M13_dom_2       
IPR018497   Peptidase_M13_C       
IPR000718   Peptidase_M13       
IPR011989   ARM-like       
IPR036322   WD40_repeat_dom_sf       
IPR038122   PFU_sf       
IPR013535   PUL_dom       
IPR015943   WD40/YVTN_repeat-like_dom_sf       
IPR015155   PFU       
IPR016024   ARM-type_fold       
IPR001680   WD40_repeat       
IPR017986   WD40_repeat_dom       
IPR016190   Transl_init_fac_IF2/IF5_Zn-bd       
IPR003307   W2_domain       
IPR002735   Transl_init_fac_IF2/IF5       
IPR016189   Transl_init_fac_IF2/IF5_N       
IPR016021   MIF4-like_sf       

SUPFAM

SSF48371   SSF48371        + More
SSF50978   SSF50978       
SSF75689   SSF75689       
SSF100966   SSF100966       

Gene 3D

1.10.1380.10     3.40.390.10     1.10.150.410     1.25.10.10     2.130.10.10     1.25.40.180    

CDD

cd08662  M13

ProteinModelPortal

Q9BLH1   H9ITE9   A0A2A4JWQ5   A0A2A4JX35   Q86RS4   A0A2U8JG00   + More
A0A2H1W5X7   A0A437B0E3   A0A1E1W8K7   A0A212F433   S4NTA7   A0A194QVE0   A0A194PTK8   A0A0L7R038   A0A139WI73   A0A139WHP0   A0A0C9RKX4   A0A0C9S0X3   A0A088AKD7   A0A0M9A0V4   K7J3Q5   N6UII9   A0A172QPK9   A0A026W1C7   A0A3L8DWD5   E0W1I2   A0A2S1TP67   E2AFA5   A0A2A3EL10   A0A154P8A9   U4U6M7   A0A1W4W608   A0A1W4WHQ7   A0A1W4W5Z7   E9IRU9   A0A1Y1K718   A0A1Y1K6C4   A0A2J7RR19   A0A1Y1K3H5   A0A1Y1K673   A0A3Q0J997   A0A232F7R6   A0A151J2K9   A0A067RF34   A0A151I329   A0A0T6BF71   A0A1I9WLF9   A0A158NUJ2   A0A2P8ZBL6   A0A0U3KDJ5   F4WRD2   A0A195C7U5   A0A2H8TNG1   A0A195FJU4   A0A2S2R687   J9JK87   A0A2S2QFC1   E2C244   A0A1Q3G120   A0A0K8TLN7   A0A182Q5Q1   A0A1S4GDN6   A0A340TB26   A0A182HGU4   Q7PY82   A0A182U1K2   A0A1S4FNM5   A0A182X2S6   A0A182VC38   A0A1Q3G159   A0A2M4CV03   A0A182J9J9   Q16UJ2   A0A0J7NSM8   A0A182NFL8   A0A1Q3G115   A0A182KMD2   A0A1L8E2J5   A0A182F8P8   A0A182JR91   A0A182LWV4   A0A1L8E2C7   A0A182VRK4   A0A1L8E257   A0A226EKZ6   A0A084VWM9   A0A182G3C1   Q8T660   A0A182P9R2   A0A1D2MVE1   A0A182XV77   A0A182T699   A0A336MVN8   A0A1B6CAF7   A0A1B6DD22   U5EU91   A0A182RNY2   W5JAQ0   A0A1B0CSU2   A0A023EVJ3  

PDB

5V48     E-value=2.27145e-54,     Score=537

KEGG

692506    K08635 neprilysin [EC:3.4.24.11] | (RefSeq) Nep-L, BmNep-L; neutral endopeptidase 24.11

GO

GO:0004222   GO:0016021   GO:0003743   GO:0006508   GO:0008237   GO:0007018   GO:0030286   GO:0006813   GO:0006810   GO:0009072   GO:0007169  

PANTHER

PTHR11733  

Length:

439

Number of predicted TMHs:

1

Exp number of AAs in TMHs:

22.46918

Exp number, first 60 AAs:

22.44323

Total prob of N-in:

0.99595

POSSIBLE N-term signal

sequence

inside

1  -  19

TMhelix

20  -  42

outside

43  -  439

 

 

Pi

19.312

Theta

16.076085

Tajima's D

-1.222666

CLR

0.110185

CSRT

0.0996950152492375

Interpretation

Uncertain