Gene

KWMTBOMO00332  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA000529

Annotation

PREDICTED:_neutral_endopeptidase_24.11_isoform_X1_[Bombyx_mori]

Location

Bomo_Chr1(-):10077367-10084978      View in EpiBrowser

Location in the cell

Cytoplasmic   Reliability : 1.845 Mitochondrial   Reliability : 1.29

CDS

ATGCGATACAGACAACAGTTTCGTAAGACTCTGACCAAGGTGGACTGGATGGATGATATGACTCGCCAAGAGGCTCTGGAGAAAGCTGATGCTATGGCTTCACACATCGCCTACCCCAGTGAAATGCTTGACAACAACAGACTCACCGAATTCTACTCTGGTCTGGAAATGTCATCGGAACACTTGATGGAGTCCGTGCTCAACTTGACATTGTTCACTACTGAGTACTTATTCGGTAAACTGAGGGAGCCCGTCAACAAGACTGACTGGGTCACCCACGGTCGCCCAGCTATCGTCAACGCTTTCTATTCGTCTATTGAGAACAGCATACAATTTCCGGCTGGTATCCTACAAGGAGCATTCTTCTCTGCCAAACGTCCTGCTTACATGAATTACGGTGCTATTGGTTTCGTCATTGGACATGAAATCACGCACGGTTTTGATGACCAGGGCCGGCAATTCGATAAAAACGGAAACCTTGTGGACTGGTGGCAGGAAATGACCAAAGAGAAGTATCTGGATAAAGCCAAATGTATCATCGATCAATACTCAAACTACACTGTTAAAGAAGTCGGATTGAAGTTGAATGGAGTGAACACACAAGGCGAGAACATTGCGGATAACGGAGGCATCAAAGAAGCTTACTACGCGTATCAAGCCTGGACTCACAGGCATGGTGAAGAAGCACGCCTGCCTGGATTGGAAAAATACAGTCCCCGACAGCTTTTCTGGCTTAGTGCTGCCAACACTTGGTGCGCAGTGTACCGCAATGAGGCAATCAAGTTGAGAATCACAACTGGATTCCATGCCCCCGGAAGATTCCGCGTCATTGGCCCCATGTCTAATATGGAAGAATTTGCCTCAGACTTCAAATGCCCTATGGGATCACCTATGAACCCTGACAAGAAATGCAAAGTGTGGTAG

Protein

MRYRQQFRKTLTKVDWMDDMTRQEALEKADAMASHIAYPSEMLDNNRLTEFYSGLEMSSEHLMESVLNLTLFTTEYLFGKLREPVNKTDWVTHGRPAIVNAFYSSIENSIQFPAGILQGAFFSAKRPAYMNYGAIGFVIGHEITHGFDDQGRQFDKNGNLVDWWQEMTKEKYLDKAKCIIDQYSNYTVKEVGLKLNGVNTQGENIADNGGIKEAYYAYQAWTHRHGEEARLPGLEKYSPRQLFWLSAANTWCAVYRNEAIKLRITTGFHAPGRFRVIGPMSNMEEFASDFKCPMGSPMNPDKKCKVW

Uniprot

Q9BLH1   H9ITE9   Q86RS4   A0A2A4JX35   A0A2U8JG00   A0A2A4JWQ5   + More
A0A212F433   A0A1E1W8K7   A0A437B0E3   A0A2H1W5X7   S4NTA7   A0A194QVE0   A0A194PTK8   A0A1E1WV53   A0A154P8A9   A0A0L7R038   A0A310SLF2   A0A0C9S0X3   A0A0C9RKX4   A0A0M9A0V4   A0A088AKD7   E2C244   A0A2A3EL10   K7J3Q5   A0A151WK54   A0A2S2R687   A0A151J2K9   A0A195FJU4   J9JK87   A0A1I9WLF9   A0A151I329   A0A2H8TNG1   A0A1B6EX18   A0A158NUJ2   E9IRU9   A0A195C7U5   A0A026W1C7   F4WRD2   A0A2J7RR27   A0A3L8DWD5   A0A139WHP0   E2AFA5   A0A1W4W608   A0A1W4W5Z7   A0A172QPK9   A0A1B6CAF7   B0WKU3   A0A1B6DD22   A0A0J7NSM8   E0W1I2   A0A2J7RR19   A0A1Q3G120   A0A1Y1K718   A0A1Q3G115   A0A1Q3G159   A0A3Q0J997   A0A1Y1K673   A0A067RF34   A0A336MVN8   A0A182RNY0   A0A023EVW7   W5JAQ0   A0A182G3C1   A0A232F7R6   A0A182P9R2   A0A182J9J9   A0A182F8P8   U4U6M7   A0A182LWV4   A0A340TB26   A0A182T699   A0A182U1K2   N6UII9   A0A2M4CV03   A0A084VWM9   A0A182VC38   A0A182VRK4   A0A182Q5Q1   A0A182XV77   A0A182NFL8   A0A182JR91   A0A1S4FNM5   A0A146LYT5   A0A0K8SBS3   A0A1S4GDN6   A0A182HGU4   Q16UJ2   Q7PY82   K7J3Q4   A0A182X2S6   A0A1L8E2J5   A0A0K8TLN7   A0A182KMD2   A0A1L8E2C7   A0A2R7W332   A0A0A1XMX9   A0A1L8E257   J9JQQ7   A0A0L0CLG4   A0A1I8M295  

Pubmed

11583934    19121390    22118469    23622113    26354079    20798317    + More
20075255    27538518    21347285    21282665    24508170    21719571    30249741    18362917    19820115    20566863    28004739    24845553    24945155    20920257    23761445    26483478    28648823    23537049    24438588    25244985    17510324    26823975    12364791    26369729    20966253    25830018    26108605    25315136   

EMBL

AB048208    BAB33300.1    BABH01007095    BABH01007096    AF413063    AAO21504.1    + More
NWSH01000486    PCG76063.1    MH298329    AWK67618.1    PCG76064.1    AGBW02010446    OWR48508.1    GDQN01007734    JAT83320.1    RSAL01000227    RVE43942.1    ODYU01006558    SOQ48505.1    GAIX01012266    JAA80294.1    KQ461108    KPJ09289.1    KQ459594    KPI96089.1    GDQN01000159    JAT90895.1    KQ434824    KZC07350.1    KQ414672    KOC64187.1    KQ762520    OAD55759.1    GBYB01014266    JAG84033.1    GBYB01007566    JAG77333.1    KQ435774    KOX75065.1    GL452067    EFN77995.1    KZ288217    PBC32410.1    KQ983014    KYQ48238.1    GGMS01016230    MBY85433.1    KQ980368    KYN16324.1    KQ981522    KYN40631.1    ABLF02019556    KU932343    APA33979.1    KQ976533    KYM81493.1    GFXV01003870    MBW15675.1    GECZ01027204    JAS42565.1    ADTU01026577    ADTU01026578    ADTU01026579    ADTU01026580    ADTU01026581    GL765283    EFZ16711.1    KQ978143    KYM96720.1    KK107496    EZA49818.1    GL888285    EGI63203.1    NEVH01000611    PNF43277.1    QOIP01000004    RLU24088.1    KQ971343    KYB27446.1    GL439090    EFN67881.1    KU245762    AND99761.1    GEDC01026857    JAS10441.1    DS231976    EDS30066.1    GEDC01013803    JAS23495.1    LBMM01001992    KMQ95435.1    DS235870    EEB19488.1    PNF43276.1    GFDL01001550    JAV33495.1    GEZM01094022    JAV56000.1    GFDL01001557    JAV33488.1    GFDL01001511    JAV33534.1    GEZM01094021    JAV56001.1    KK852675    KDR18716.1    UFQS01003165    UFQT01003165    SSX15299.1    SSX34674.1    GAPW01000331    JAC13267.1    ADMH02001926    ETN60478.1    JXUM01040714    JXUM01040715    JXUM01040716    JXUM01040717    JXUM01040718    JXUM01040719    JXUM01040720    NNAY01000760    OXU26642.1    KB632006    ERL87973.1    AXCM01000914    APGK01034174    APGK01034175    APGK01034176    APGK01034177    APGK01034178    KB740904    ENN78462.1    GGFL01004490    MBW68668.1    ATLV01017670    KE525181    KFB42373.1    AXCN02000208    GDHC01006833    JAQ11796.1    GBRD01015302    JAG50524.1    AAAB01008987    APCN01005946    CH477621    EAT38188.1    EAA01126.5    GFDF01001146    JAV12938.1    GDAI01002525    JAI15078.1    GFDF01001260    JAV12824.1    KK854278    PTY14137.1    GBXI01001946    GBXI01001592    JAD12346.1    JAD12700.1    GFDF01001261    JAV12823.1    ABLF02033036    ABLF02033037    JRES01000236    KNC33072.1   

Proteomes

UP000005204    UP000218220    UP000007151    UP000283053    UP000053240    UP000053268    + More
UP000076502    UP000053825    UP000053105    UP000005203    UP000008237    UP000242457    UP000002358    UP000075809    UP000078492    UP000078541    UP000007819    UP000078540    UP000005205    UP000078542    UP000053097    UP000007755    UP000235965    UP000279307    UP000007266    UP000000311    UP000192223    UP000002320    UP000036403    UP000009046    UP000079169    UP000027135    UP000075900    UP000000673    UP000069940    UP000215335    UP000075885    UP000075880    UP000069272    UP000030742    UP000075883    UP000075903    UP000075901    UP000075902    UP000019118    UP000030765    UP000075920    UP000075886    UP000076408    UP000075884    UP000075881    UP000075840    UP000008820    UP000007062    UP000076407    UP000075882    UP000037069    UP000095301   

PRIDE

Q9BLH1    H9ITE9   

Pfam

PF01431   Peptidase_M13        + More
PF05649   Peptidase_M13_N
PF08324   PUL
PF09070   PFU
PF00400   WD40

Interpro

IPR024079   MetalloPept_cat_dom_sf        + More
IPR008753   Peptidase_M13_N       
IPR042089   Peptidase_M13_dom_2       
IPR018497   Peptidase_M13_C       
IPR000718   Peptidase_M13       
IPR042116   TypA/BipA_C       
IPR011989   ARM-like       
IPR036322   WD40_repeat_dom_sf       
IPR038122   PFU_sf       
IPR013535   PUL_dom       
IPR015943   WD40/YVTN_repeat-like_dom_sf       
IPR015155   PFU       
IPR016024   ARM-type_fold       
IPR001680   WD40_repeat       
IPR017986   WD40_repeat_dom       

SUPFAM

SSF48371   SSF48371        + More
SSF50978   SSF50978       

Gene 3D

1.10.1380.10     3.40.390.10     2.40.50.250     1.10.150.410     1.25.10.10     2.130.10.10    

CDD

cd08662  M13

ProteinModelPortal

Q9BLH1   H9ITE9   Q86RS4   A0A2A4JX35   A0A2U8JG00   A0A2A4JWQ5   + More
A0A212F433   A0A1E1W8K7   A0A437B0E3   A0A2H1W5X7   S4NTA7   A0A194QVE0   A0A194PTK8   A0A1E1WV53   A0A154P8A9   A0A0L7R038   A0A310SLF2   A0A0C9S0X3   A0A0C9RKX4   A0A0M9A0V4   A0A088AKD7   E2C244   A0A2A3EL10   K7J3Q5   A0A151WK54   A0A2S2R687   A0A151J2K9   A0A195FJU4   J9JK87   A0A1I9WLF9   A0A151I329   A0A2H8TNG1   A0A1B6EX18   A0A158NUJ2   E9IRU9   A0A195C7U5   A0A026W1C7   F4WRD2   A0A2J7RR27   A0A3L8DWD5   A0A139WHP0   E2AFA5   A0A1W4W608   A0A1W4W5Z7   A0A172QPK9   A0A1B6CAF7   B0WKU3   A0A1B6DD22   A0A0J7NSM8   E0W1I2   A0A2J7RR19   A0A1Q3G120   A0A1Y1K718   A0A1Q3G115   A0A1Q3G159   A0A3Q0J997   A0A1Y1K673   A0A067RF34   A0A336MVN8   A0A182RNY0   A0A023EVW7   W5JAQ0   A0A182G3C1   A0A232F7R6   A0A182P9R2   A0A182J9J9   A0A182F8P8   U4U6M7   A0A182LWV4   A0A340TB26   A0A182T699   A0A182U1K2   N6UII9   A0A2M4CV03   A0A084VWM9   A0A182VC38   A0A182VRK4   A0A182Q5Q1   A0A182XV77   A0A182NFL8   A0A182JR91   A0A1S4FNM5   A0A146LYT5   A0A0K8SBS3   A0A1S4GDN6   A0A182HGU4   Q16UJ2   Q7PY82   K7J3Q4   A0A182X2S6   A0A1L8E2J5   A0A0K8TLN7   A0A182KMD2   A0A1L8E2C7   A0A2R7W332   A0A0A1XMX9   A0A1L8E257   J9JQQ7   A0A0L0CLG4   A0A1I8M295  

PDB

5V48     E-value=1.06139e-78,     Score=745

KEGG

692506    K08635 neprilysin [EC:3.4.24.11] | (RefSeq) Nep-L, BmNep-L; neutral endopeptidase 24.11

GO

GO:0004222   GO:0016021   GO:0006508   GO:0008237   GO:0007018   GO:0030286   GO:0006813   GO:0006810   GO:0009072   GO:0007169  

PANTHER

PTHR11733  

Length:

307

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.74965

Exp number, first 60 AAs:

0.00137

Total prob of N-in:

0.32173

outside

1  -  307

 

 

Pi

4.904208

Theta

12.462965

Tajima's D

-1.333845

CLR

0

CSRT

0.0821458927053647

Interpretation

Uncertain