Gene

KWMTBOMO00312

Pre Gene Modal

BGIBMGA000688

Annotation

potassium-dependent_sodium-calcium_exchanger_[Danaus_plexippus]

Location

Bomo_Chr1(+):9731705-9740648      View in EpiBrowser

Location in the cell

PlasmaMembrane   Reliability : 4.903

CDS

ATGCTCATAAGGACTAGACAATATGAACGTAAACATAGAGTTGCGACAATAGTGCGTGTGGTTTTGTTTTTCGGCATCCCTATTGTTTATATGGTGGCAAAATCTATTGCAAGCAATCAAGTTATCGTTTTTGATGAACCTGAGGCGTTTTCGTCGCGGCATCTTCTGGGCATCGTAGAGATTGAAAGGAACTGCACTCCAGCAGCTATCCTTGAGTTTCCATCTGACGGCTTGACACGTTTCCAAAGGCAACATGGCTTCATACTGTTACACTGTTTTCTAGCTTTGTACTGTTTTCTACTGCTCGGTAGTGTTTGCGAAGATTATTTCGTACCGGCCATTGAAATTATTTGCGAGCGTTTAAACATAGCTTCGGATATCGCAGGCGCAACTTTCATGGCAGCAGCCAGTTCAAGCCCAGAGTTGTTCATTAATTGCGTGGGTACCTTCGTCACTGAAGGAGATCTGGGCGTTGGTGCTGTGGTTGGGTCTGCAGTTTTCAATGTCTTAGCAGTTCCGGCATGCTGCGCGCTTTTCGCTGGGGCAGTAATAGAATTGGACTGGTGGTCAGTCACCAGGGATTGCATGATGTACGCAGTTGCCGTGGTCGCCCTTATCTTGACTCTCCTCGATGACAAAATATACTGGCACGAAGCTCTGCTTCTCGTACTTATGTACACATTTTATATATTAGCAATGGTTTTCAACAATCGACTGGGTTCAGTGGTCAAGAGAGGCTGTTGTTTTTTCAAAAAGTCCAAAACATACACTGAAGTCACACCACTACTCATCAAAGAAAAAATCAACCCTTTAGATGCATCACAACGTATGACGCCCCGTTCTGTTCAAAACGGTGACCTGGAGCGAGGAATAGAAATGACGAGAAGACACGATTCTACGGGATCAGATATAAGCACTAGCTCAGTTTGGTCTTTTCCTGGCGATAAGATATCATTTTGGAAGAAATTATTCTGGGTACTGACATGGCCGATTCGACTTATCCTTTGGGCTACAATACCCGACTGCAGGCATCGACACAGCATTTATCCTCTAACCTTCATCATGTGTATTACGTGGATAGGCAGTGTGTCTTACCTAGTCGCTTGGATAATTACTGTTGTTGGCGACACTCTGAACGTTCCCGACAGTATAACAGGACTTACGATTCTCGCAGCTGGTACAAGTCTCCCTGAAGCAGTTTCAAGCGTTCTCGTTACTAAACAAGGGCACGGCACAATGGGTATAAGCAACTCAATTGGATCCAACACATTCGACATATTACTGTGCTTAGGACTGCCATGGCTAGTGAAGTCATTGTTTTATCCAAGCACTCCAGAAAACCATTGGGTTACAATAAATTCTAGCGGTCTGTCCTACAGTGTAATCTCACTTCTATCGACTTTATTCGCGCTGTACGGATGTCTTTCACTCAACAAGTTTCAATTAGATTGGAAGGTTGGCATTACATGCAGCGTTGTATATGCCGGTTTCTTAACTTTGGCTGCTTTGATTGAGCTCAATGTGTTTTTTGTTGTCAATCTACCTGTTTGCCCACATTAA

Protein

MLIRTRQYERKHRVATIVRVVLFFGIPIVYMVAKSIASNQVIVFDEPEAFSSRHLLGIVEIERNCTPAAILEFPSDGLTRFQRQHGFILLHCFLALYCFLLLGSVCEDYFVPAIEIICERLNIASDIAGATFMAAASSSPELFINCVGTFVTEGDLGVGAVVGSAVFNVLAVPACCALFAGAVIELDWWSVTRDCMMYAVAVVALILTLLDDKIYWHEALLLVLMYTFYILAMVFNNRLGSVVKRGCCFFKKSKTYTEVTPLLIKEKINPLDASQRMTPRSVQNGDLERGIEMTRRHDSTGSDISTSSVWSFPGDKISFWKKLFWVLTWPIRLILWATIPDCRHRHSIYPLTFIMCITWIGSVSYLVAWIITVVGDTLNVPDSITGLTILAAGTSLPEAVSSVLVTKQGHGTMGISNSIGSNTFDILLCLGLPWLVKSLFYPSTPENHWVTINSSGLSYSVISLLSTLFALYGCLSLNKFQLDWKVGITCSVVYAGFLTLAALIELNVFFVVNLPVCPH

Similarity

Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.

Uniprot

H9ITV8   A0A212FHH2   A0A194PTE1   A0A182VJF5   A0A2C9GR83   A0A182KKF8   + More
A0A182GKT5   Q17BT6   A7US87   A0A1S4F8Y6   A0A182MFF6   A0A232EVX1   A0A182QQ45   T1DK51   K7J6N9   A0A182KC26   D6WM88   A0A182JA64   W5JX63   B0WBJ1   A0A1Q3FQ27   A0A1Q3FQS1   A0A084V9V8   A0A195ERU2   A0A182Y9L9   A0A1L8DK88   A0A182N2P3   A0A182WUK7   A0A194QVK3   A0A0C9R500   A0A158NTK2   F4WQW7   A0A1Y1MAT2   A0A088AGL9   A0A3L8DJZ5   A0A1Y1KUE6   A0A182PDA0   A0A224XMZ1   A0A154PNW4   A0A1W4WQZ2   A0A1Y1NCJ3   A0A0L7RBA1   A0A1B0GMI3   A0A2A3E0V9   A0A023EZI4   U4UHH2   A0A067R9D8   A0A0A9XWU9   A0A2J7QAG0   A0A1B6D9C7   N6TU45   A0A067RBZ5   A0A1L8DJM0   A0A182WE41   E0VRF0   A0A1B6JE47   A0A1B6FZ48   A0A1B6KAW2   A0A1I8MXX2   A0A182FV54   A0A336MRQ3   A0A336MPD3   A0A336L3M4   A0A1I8MJH1   A0A336MPI2   A0A1I8P394   A0A0L0BYW8   A0A1A9ZGM9   A0A026WN08   A0A226EM38   A0A226DG03   A0A1B6LX38   A0A1B6II84   A0A1B6GPI9   T1JCX0   A0A088AGL8   A0A1A9VRJ3   A0A0P5K281   A0A0P5SCF5   A0A067R056   A0A2A3E1A4   A0A0P5QD66   E9G011   A0A2J7QAI7   V5HCF5   A0A131Y219   A0A210QG44   A0A1S3H8R1   A0A293MC35   E2AFX9   A0A0C9RHY4   E2C4F0   V5ICK9   A0A0H3YKA3   A0A1E1XPG6   V4B2B8   A0A1E1X298   A0A0H3YJ53   C3ZMW2  

Pubmed

19121390    22118469    26354079    20966253    26483478    17510324    + More
12364791    14747013    17210077    28648823    20075255    18362917    19820115    20920257    23761445    24438588    25244985    21347285    21719571    28004739    30249741    25474469    23537049    24845553    25401762    26823975    20566863    25315136    26108605    24508170    21292972    25765539    28812685    20798317    26057828    29209593    23254933    28503490    18563158   

EMBL

BABH01007068    AGBW02008503    OWR53183.1    KQ459594    KPI96029.1    APCN01001433    + More
JXUM01070745    JXUM01070746    JXUM01070747    JXUM01070748    KQ562624    KXJ75462.1    CH477316    EAT43777.1    AAAB01008823    EDO64434.1    AXCM01008494    NNAY01001938    OXU22505.1    AXCN02001080    GAMD01001121    JAB00470.1    KQ971343    EFA03342.1    ADMH02000090    ETN67854.1    DS231879    EDS42430.1    GFDL01005378    JAV29667.1    GFDL01005252    JAV29793.1    ATLV01000460    KE523882    KFB34752.1    KQ981993    KYN30943.1    GFDF01007309    JAV06775.1    KQ461108    KPJ09354.1    GBYB01001920    GBYB01001921    JAG71687.1    JAG71688.1    ADTU01025989    GL888275    EGI63480.1    GEZM01036147    JAV82939.1    QOIP01000007    RLU20727.1    GEZM01073531    JAV65023.1    GFTR01006474    JAW09952.1    KQ434977    KZC12948.1    GEZM01007300    GEZM01007299    JAV95258.1    KQ414617    KOC68021.1    AJVK01011474    AJVK01011475    KZ288496    PBC25184.1    GBBI01004059    JAC14653.1    KB632303    ERL91813.1    KK852804    KDR16219.1    GBHO01020256    GBRD01011629    GDHC01019424    JAG23348.1    JAG54195.1    JAP99204.1    NEVH01016330    PNF25571.1    GEDC01015015    JAS22283.1    APGK01018911    KB740085    ENN81548.1    KDR16218.1    GFDF01007431    JAV06653.1    DS235465    EEB15956.1    GECU01010473    JAS97233.1    GECZ01024111    GECZ01014292    JAS45658.1    JAS55477.1    GEBQ01031390    GEBQ01026499    GEBQ01018163    GEBQ01007137    JAT08587.1    JAT13478.1    JAT21814.1    JAT32840.1    UFQT01002006    SSX32385.1    SSX32384.1    UFQS01001835    UFQT01001835    SSX12508.1    SSX31951.1    SSX12507.1    SSX31950.1    JRES01001143    KNC25186.1    KK107152    EZA57031.1    LNIX01000003    OXA58755.1    LNIX01000019    OXA44472.1    GEBQ01029570    GEBQ01011783    GEBQ01005432    GEBQ01003374    JAT10407.1    JAT28194.1    JAT34545.1    JAT36603.1    GECU01021079    JAS86627.1    GECZ01005439    GECZ01002919    JAS64330.1    JAS66850.1    JH432085    GDIQ01190263    JAK61462.1    GDIP01141899    LRGB01001581    JAL61815.1    KZS11437.1    KDR16220.1    KZ288460    PBC25477.1    GDIQ01118836    JAL32890.1    GL732528    EFX87145.1    PNF25582.1    GANP01009434    JAB75034.1    GEFM01003281    JAP72515.1    NEDP02003819    OWF47714.1    GFWV01018579    MAA43307.1    GL439180    EFN67655.1    GBYB01006561    GBYB01006562    JAG76328.1    JAG76329.1    GL452462    EFN77187.1    GANP01013507    JAB70961.1    KT163618    AKN21568.1    GFAA01002573    JAU00862.1    KB203888    ESO82454.1    GFAC01005805    JAT93383.1    KT163616    AKN21566.1    GG666648    EEN46102.1   

Proteomes

UP000005204    UP000007151    UP000053268    UP000075903    UP000075840    UP000075882    + More
UP000069940    UP000249989    UP000008820    UP000007062    UP000075883    UP000215335    UP000075886    UP000002358    UP000075881    UP000007266    UP000075880    UP000000673    UP000002320    UP000030765    UP000078541    UP000076408    UP000075884    UP000076407    UP000053240    UP000005205    UP000007755    UP000005203    UP000279307    UP000075885    UP000076502    UP000192223    UP000053825    UP000092462    UP000242457    UP000030742    UP000027135    UP000235965    UP000019118    UP000075920    UP000009046    UP000095301    UP000069272    UP000095300    UP000037069    UP000092445    UP000053097    UP000198287    UP000078200    UP000076858    UP000000305    UP000242188    UP000085678    UP000000311    UP000008237    UP000030746    UP000001554   

PRIDE

H9ITV8   

Pfam

PF01699   Na_Ca_ex        + More
PF00024   PAN_1

Interpro

IPR004481   K/Na/Ca-exchanger        + More
IPR004837   NaCa_Exmemb       
IPR004836   Na_Ca_Ex       
IPR003609   Pan_app       

ProteinModelPortal

H9ITV8   A0A212FHH2   A0A194PTE1   A0A182VJF5   A0A2C9GR83   A0A182KKF8   + More
A0A182GKT5   Q17BT6   A7US87   A0A1S4F8Y6   A0A182MFF6   A0A232EVX1   A0A182QQ45   T1DK51   K7J6N9   A0A182KC26   D6WM88   A0A182JA64   W5JX63   B0WBJ1   A0A1Q3FQ27   A0A1Q3FQS1   A0A084V9V8   A0A195ERU2   A0A182Y9L9   A0A1L8DK88   A0A182N2P3   A0A182WUK7   A0A194QVK3   A0A0C9R500   A0A158NTK2   F4WQW7   A0A1Y1MAT2   A0A088AGL9   A0A3L8DJZ5   A0A1Y1KUE6   A0A182PDA0   A0A224XMZ1   A0A154PNW4   A0A1W4WQZ2   A0A1Y1NCJ3   A0A0L7RBA1   A0A1B0GMI3   A0A2A3E0V9   A0A023EZI4   U4UHH2   A0A067R9D8   A0A0A9XWU9   A0A2J7QAG0   A0A1B6D9C7   N6TU45   A0A067RBZ5   A0A1L8DJM0   A0A182WE41   E0VRF0   A0A1B6JE47   A0A1B6FZ48   A0A1B6KAW2   A0A1I8MXX2   A0A182FV54   A0A336MRQ3   A0A336MPD3   A0A336L3M4   A0A1I8MJH1   A0A336MPI2   A0A1I8P394   A0A0L0BYW8   A0A1A9ZGM9   A0A026WN08   A0A226EM38   A0A226DG03   A0A1B6LX38   A0A1B6II84   A0A1B6GPI9   T1JCX0   A0A088AGL8   A0A1A9VRJ3   A0A0P5K281   A0A0P5SCF5   A0A067R056   A0A2A3E1A4   A0A0P5QD66   E9G011   A0A2J7QAI7   V5HCF5   A0A131Y219   A0A210QG44   A0A1S3H8R1   A0A293MC35   E2AFX9   A0A0C9RHY4   E2C4F0   V5ICK9   A0A0H3YKA3   A0A1E1XPG6   V4B2B8   A0A1E1X298   A0A0H3YJ53   C3ZMW2  

PDB

3V5U     E-value=3.64098e-05,     Score=114

KEGG

101739975    no KO assigned | (RefSeq) sodium/potassium/calcium exchanger 4-like

GO

GO:0016021   GO:0055085   GO:0005887   GO:0005262   GO:0006874   GO:0070588   GO:0008273   GO:0005432   GO:0005802   GO:0006816   GO:0016020   GO:0005737   GO:0006813   GO:0006810   GO:0009072   GO:0007169  

PANTHER

PTHR10846  

Length:

519

Number of predicted TMHs:

11

Exp number of AAs in TMHs:

230.60578

Exp number, first 60 AAs:

21.84435

Total prob of N-in:

0.88445

POSSIBLE N-term signal

sequence

inside

1  -  19

TMhelix

20  -  42

outside

43  -  86

TMhelix

87  -  106

inside

107  -  126

TMhelix

127  -  144

outside

145  -  158

TMhelix

159  -  181

inside

182  -  187

TMhelix

188  -  210

outside

211  -  213

TMhelix

214  -  236

inside

237  -  350

TMhelix

351  -  373

outside

374  -  382

TMhelix

383  -  405

inside

406  -  413

TMhelix

414  -  436

outside

437  -  455

TMhelix

456  -  478

inside

479  -  489

TMhelix

490  -  512

outside

513  -  519

 

 

Pi

2.008544

Theta

4.887076

Tajima's D

-2.548513

CLR

0.139912

CSRT

0.000199990000499975

Interpretation

Possibly Positive selection