Gene
KWMTBOMO00299
Pre Gene Modal
BGIBMGA000682
Annotation
PREDICTED:_ras-related_protein_Rab-21_[Amyelois_transitella]
Full name
Ras-related protein Rab-21
Location in the cell
Nuclear Reliability : 1.954
Sequence
CDS
ATGACTACTACGACTGGAGGTGCACGAAATTTTAAAGTAGTTCTTTTGGGTGACGGATGTGTCGGAAAAACTTCATTATTATTGCGTTACATTGAAGATAAATTTAACGAAAAGCATCTGACTACGCTTCAGGCCACATTCTTAAATAAAAGGTTGAATATTAATGGAAATCGTGTCAATCTTTCCATTTGGGATACAGCTGGCCAGGAGAAGTTTCATGCTCTGGGACCAATATACTACAGAAACTCTAATGGTGCGATTCTGGTTTACGATATTACTGATGAAGATTCATTTAGAAAGGTAAAAAATTGGGTGAAAGAATTGAAGAAAATGTTGGGATCAGATATTAATCTGGTAATTGCAGGAAATAAAATAGACCTTGAACATGAACGCACTGTTTCACTAGAAGAAGCAGAAAGCTATGCAAAATTAGTAGGAGCTAAACATTATTACACTTCAGCAAAATTAAACCAGGGTGTTGAAGAATTGTTTCTTGACTTGACTAGAGAAATGTTGGAAAGACAAGAACACAATACACAGACTGAAGTAAACAGAACATCACAAGTTGTAGTAGTCGATGATGAGGTACCTGTGCAATCAACCTGCTGTTCAGGACACAGGAGTTCCTAA
Protein
MTTTTGGARNFKVVLLGDGCVGKTSLLLRYIEDKFNEKHLTTLQATFLNKRLNINGNRVNLSIWDTAGQEKFHALGPIYYRNSNGAILVYDITDEDSFRKVKNWVKELKKMLGSDINLVIAGNKIDLEHERTVSLEEAESYAKLVGAKHYYTSAKLNQGVEELFLDLTREMLERQEHNTQTEVNRTSQVVVVDDEVPVQSTCCSGHRSS
Summary
Description
Regulates integrin internalization and recycling, but does not influence the traffic of endosomally translocated receptors in general (By similarity). As a result, may regulate cell adhesion and migration (By similarity). During the mitosis of adherent cells, controls the endosomal trafficking of integrins which is required for the successful completion of cytokinesis (PubMed:18804435). Involved in neurite growth (By similarity). Following SBF2/MTMT13-mediated activation in response to starvation-induced autophagy, binds to and regulates SNARE protein VAMP8 endolysosomal transport required for SNARE-mediated autophagosome-lysosome fusion (PubMed:25648148).
Subunit
Interacts with the cytoplasmic tail of integrins ITGA1, ITGA2, ITGA5, ITGA6, ITGA11 and ITGB1 (By similarity). Interacts with RABGEF1 (via VPS9 domain) (PubMed:17450153). Interacts with ANKRD27 (PubMed:16525121, PubMed:18477474). Interacts with VAMP7 (PubMed:25648148). Interacts (in GTP-bound form) with VAMP8 in response to starvation; the interaction probably regulates VAMP8 endolysosomal trafficking (PubMed:25648148).
Similarity
Belongs to the small GTPase superfamily. Rab family.
Keywords
3D-structure
Acetylation
Complete proteome
Cytoplasmic vesicle
Direct protein sequencing
Endoplasmic reticulum
Endosome
Golgi apparatus
GTP-binding
Lipoprotein
Membrane
Methylation
Nucleotide-binding
Prenylation
Protein transport
Reference proteome
Transport
Feature
chain Ras-related protein Rab-21
propeptide Removed in mature form
propeptide Removed in mature form
Uniprot
A0A2H1WC25
A0A212ETH2
A0A0L7KXG3
A0A067RMB1
A0A2J7QEG0
A0A194QUR2
+ More
A0A210Q8C3 A0A194PRP1 E1ZVU2 A0A0J7KIL0 A0A151I979 A0A0N7ZDJ1 A0A3M6UZ49 A0A1B6CP69 A0A1B6GBG8 A0A195F604 A0A2B4SR10 A0A195AY94 A0A158NYD1 F4WSZ1 A0A154PLL1 E9JCX4 A0A026VYD3 A0A151IUF2 E2BNQ7 A7SMT0 A0A232F5W3 K7IW40 A0A2I2ZNM3 A0A1B6KRA1 A0A0C9QIF0 T2M3Z8 A0A1S3SJ12 A0A3N0Z1Q8 A0A3P9IVQ8 A0A1W5AF17 A0A224XW91 A0A069DQW3 A0A2K5VLM3 K1PDE3 A0A146Z1E3 G3RGT8 A0A3B3QL17 A0A3P9NFY5 J9KAJ6 M4A7J5 D6WE58 A6YPJ0 U6DEF9 A0A170YS21 A0A3B3QPU6 G9KJR5 W5URF0 A0A2I2YNL4 R4WIM0 A0A3P8PFT1 A0A3B3Z2R0 A0A087XZ46 A0A3B3V562 A0A3B4FXR6 A0A1A7X8I1 A0A1A8JPM6 A0A1A8BQN6 A0A1A8FBV3 A0A1A8VBL2 I3KNT0 A0A3P9D153 A0A3P8ZZF1 A0A1A8PD54 A0A1A8PHU4 A0A2S2NKF0 H3C2P0 A0A2R9CJ64 H2Q6H2 Q4TC69 A0A3P9LTL0 F1PGI1 W5P3L8 A0A2K5YP81 A0A096MUF5 A0A2K5LAB6 A0A2K5HAS3 A0A2R9CLV3 A0A2I3TNY4 A0A3B5AA10 G1QWN6 U3DY75 A0A024RBA9 Q9UL25 A0A151PFL0 A0A2J8W1K2 A0A0B7ANE7 Q08BX0 A0A3B4CWL6 A0A3B4XP57 A0A3B4UPG1 A0A3B3DZ92 A0A2R7VSH7 L8IHK4 A0A3B1JD19
A0A210Q8C3 A0A194PRP1 E1ZVU2 A0A0J7KIL0 A0A151I979 A0A0N7ZDJ1 A0A3M6UZ49 A0A1B6CP69 A0A1B6GBG8 A0A195F604 A0A2B4SR10 A0A195AY94 A0A158NYD1 F4WSZ1 A0A154PLL1 E9JCX4 A0A026VYD3 A0A151IUF2 E2BNQ7 A7SMT0 A0A232F5W3 K7IW40 A0A2I2ZNM3 A0A1B6KRA1 A0A0C9QIF0 T2M3Z8 A0A1S3SJ12 A0A3N0Z1Q8 A0A3P9IVQ8 A0A1W5AF17 A0A224XW91 A0A069DQW3 A0A2K5VLM3 K1PDE3 A0A146Z1E3 G3RGT8 A0A3B3QL17 A0A3P9NFY5 J9KAJ6 M4A7J5 D6WE58 A6YPJ0 U6DEF9 A0A170YS21 A0A3B3QPU6 G9KJR5 W5URF0 A0A2I2YNL4 R4WIM0 A0A3P8PFT1 A0A3B3Z2R0 A0A087XZ46 A0A3B3V562 A0A3B4FXR6 A0A1A7X8I1 A0A1A8JPM6 A0A1A8BQN6 A0A1A8FBV3 A0A1A8VBL2 I3KNT0 A0A3P9D153 A0A3P8ZZF1 A0A1A8PD54 A0A1A8PHU4 A0A2S2NKF0 H3C2P0 A0A2R9CJ64 H2Q6H2 Q4TC69 A0A3P9LTL0 F1PGI1 W5P3L8 A0A2K5YP81 A0A096MUF5 A0A2K5LAB6 A0A2K5HAS3 A0A2R9CLV3 A0A2I3TNY4 A0A3B5AA10 G1QWN6 U3DY75 A0A024RBA9 Q9UL25 A0A151PFL0 A0A2J8W1K2 A0A0B7ANE7 Q08BX0 A0A3B4CWL6 A0A3B4XP57 A0A3B4UPG1 A0A3B3DZ92 A0A2R7VSH7 L8IHK4 A0A3B1JD19
Pubmed
22118469
26227816
24845553
26354079
28812685
20798317
+ More
30382153 21347285 21719571 21282665 24508170 30249741 17615350 28648823 20075255 22398555 24065732 17554307 26334808 22992520 29240929 23542700 18362917 19820115 18207082 23236062 23127152 23691247 25186727 25069045 15496914 22722832 16136131 16341006 20809919 25243066 11181995 10887961 15489334 7788527 15561770 16525121 18477474 18804435 19413330 19745841 21269460 22814378 25648148 25944712 16034420 17450153 22293439 23594743 29451363 22751099 25329095
30382153 21347285 21719571 21282665 24508170 30249741 17615350 28648823 20075255 22398555 24065732 17554307 26334808 22992520 29240929 23542700 18362917 19820115 18207082 23236062 23127152 23691247 25186727 25069045 15496914 22722832 16136131 16341006 20809919 25243066 11181995 10887961 15489334 7788527 15561770 16525121 18477474 18804435 19413330 19745841 21269460 22814378 25648148 25944712 16034420 17450153 22293439 23594743 29451363 22751099 25329095
EMBL
ODYU01007654
SOQ50618.1
AGBW02012593
OWR44777.1
JTDY01004809
KOB67724.1
+ More
KK852542 KDR21730.1 NEVH01015312 PNF26974.1 KQ461108 KPJ09268.1 NEDP02004628 OWF45002.1 KQ459594 KPI96116.1 GL434640 EFN74693.1 LBMM01007086 KMQ90056.1 KQ978296 KYM95365.1 GDRN01035670 JAI67392.1 RCHS01000416 RMX58945.1 GEDC01025463 GEDC01022032 GEDC01000449 JAS11835.1 JAS15266.1 JAS36849.1 GECZ01009995 JAS59774.1 KQ981768 KYN36020.1 LSMT01000034 PFX31513.1 KQ976701 KYM77213.1 ADTU01003758 GL888331 EGI62695.1 KQ434938 KZC12110.1 GL771866 EFZ09181.1 KK107579 QOIP01000004 EZA48655.1 RLU23562.1 KQ980963 KYN11022.1 GL449444 EFN82666.1 DS469712 EDO34991.1 NNAY01000840 OXU26246.1 CABD030085385 CABD030085386 CABD030085387 GEBQ01025995 JAT13982.1 GBYB01000362 JAG70129.1 HAAD01000398 CDG66630.1 RJVU01017312 ROL52173.1 GFTR01003676 JAW12750.1 GBGD01002852 JAC86037.1 AQIA01011595 AQIA01011596 AQIA01011597 JH817881 EKC19528.1 GCES01026162 JAR60161.1 ABLF02029119 KQ971318 EFA00389.1 EF639001 ABR27886.1 HAAF01008698 CCP80522.1 GEMB01003017 JAS00187.1 JP016546 AES05144.1 JT416918 AHH42193.1 AK417285 BAN20500.1 AYCK01016789 HADW01013017 HADX01004132 SBP14417.1 HAED01012712 HAEE01001294 SBR21310.1 HADZ01004889 HAEA01012857 SBP68830.1 HAEB01009092 HAEC01012925 SBQ55619.1 HADY01002399 HAEJ01017582 SBS58039.1 AERX01019379 AERX01019380 AERX01019381 HAEI01002149 HAEH01010717 SBR79158.1 HAEF01008262 HAEG01008099 SBR80975.1 GGMR01004999 MBY17618.1 AJFE02118460 AJFE02118461 AACZ04072005 CAAE01007048 CAF89513.1 AAEX03007069 AMGL01039465 AHZZ02002464 NBAG03000393 PNI29901.1 ADFV01185858 ADFV01185859 GAMT01007263 GAMR01003862 GAMQ01004684 GAMP01008523 JAB04598.1 JAB30070.1 JAB37167.1 JAB44232.1 CH471054 EAW97271.1 AF091035 BC021901 BC092475 D42087 AKHW03000416 KYO47772.1 NDHI03003404 PNJ63576.1 HACG01034636 CEK81501.1 CABZ01072520 CABZ01072521 CABZ01085404 BC124522 BC165035 AAI24523.1 AAI65035.1 KK854042 PTY10118.1 JH881226 ELR55633.1
KK852542 KDR21730.1 NEVH01015312 PNF26974.1 KQ461108 KPJ09268.1 NEDP02004628 OWF45002.1 KQ459594 KPI96116.1 GL434640 EFN74693.1 LBMM01007086 KMQ90056.1 KQ978296 KYM95365.1 GDRN01035670 JAI67392.1 RCHS01000416 RMX58945.1 GEDC01025463 GEDC01022032 GEDC01000449 JAS11835.1 JAS15266.1 JAS36849.1 GECZ01009995 JAS59774.1 KQ981768 KYN36020.1 LSMT01000034 PFX31513.1 KQ976701 KYM77213.1 ADTU01003758 GL888331 EGI62695.1 KQ434938 KZC12110.1 GL771866 EFZ09181.1 KK107579 QOIP01000004 EZA48655.1 RLU23562.1 KQ980963 KYN11022.1 GL449444 EFN82666.1 DS469712 EDO34991.1 NNAY01000840 OXU26246.1 CABD030085385 CABD030085386 CABD030085387 GEBQ01025995 JAT13982.1 GBYB01000362 JAG70129.1 HAAD01000398 CDG66630.1 RJVU01017312 ROL52173.1 GFTR01003676 JAW12750.1 GBGD01002852 JAC86037.1 AQIA01011595 AQIA01011596 AQIA01011597 JH817881 EKC19528.1 GCES01026162 JAR60161.1 ABLF02029119 KQ971318 EFA00389.1 EF639001 ABR27886.1 HAAF01008698 CCP80522.1 GEMB01003017 JAS00187.1 JP016546 AES05144.1 JT416918 AHH42193.1 AK417285 BAN20500.1 AYCK01016789 HADW01013017 HADX01004132 SBP14417.1 HAED01012712 HAEE01001294 SBR21310.1 HADZ01004889 HAEA01012857 SBP68830.1 HAEB01009092 HAEC01012925 SBQ55619.1 HADY01002399 HAEJ01017582 SBS58039.1 AERX01019379 AERX01019380 AERX01019381 HAEI01002149 HAEH01010717 SBR79158.1 HAEF01008262 HAEG01008099 SBR80975.1 GGMR01004999 MBY17618.1 AJFE02118460 AJFE02118461 AACZ04072005 CAAE01007048 CAF89513.1 AAEX03007069 AMGL01039465 AHZZ02002464 NBAG03000393 PNI29901.1 ADFV01185858 ADFV01185859 GAMT01007263 GAMR01003862 GAMQ01004684 GAMP01008523 JAB04598.1 JAB30070.1 JAB37167.1 JAB44232.1 CH471054 EAW97271.1 AF091035 BC021901 BC092475 D42087 AKHW03000416 KYO47772.1 NDHI03003404 PNJ63576.1 HACG01034636 CEK81501.1 CABZ01072520 CABZ01072521 CABZ01085404 BC124522 BC165035 AAI24523.1 AAI65035.1 KK854042 PTY10118.1 JH881226 ELR55633.1
Proteomes
UP000007151
UP000037510
UP000027135
UP000235965
UP000053240
UP000242188
+ More
UP000053268 UP000000311 UP000036403 UP000078542 UP000275408 UP000078541 UP000225706 UP000078540 UP000005205 UP000007755 UP000076502 UP000053097 UP000279307 UP000078492 UP000008237 UP000001593 UP000215335 UP000002358 UP000001519 UP000087266 UP000265200 UP000192224 UP000233100 UP000005408 UP000265000 UP000261540 UP000242638 UP000007819 UP000002852 UP000007266 UP000221080 UP000265100 UP000261480 UP000028760 UP000261500 UP000261460 UP000005207 UP000265160 UP000265140 UP000007303 UP000240080 UP000002277 UP000265180 UP000002254 UP000002356 UP000233140 UP000028761 UP000233060 UP000233080 UP000261400 UP000001073 UP000008225 UP000005640 UP000050525 UP000000437 UP000261440 UP000261360 UP000261420 UP000261560 UP000018467
UP000053268 UP000000311 UP000036403 UP000078542 UP000275408 UP000078541 UP000225706 UP000078540 UP000005205 UP000007755 UP000076502 UP000053097 UP000279307 UP000078492 UP000008237 UP000001593 UP000215335 UP000002358 UP000001519 UP000087266 UP000265200 UP000192224 UP000233100 UP000005408 UP000265000 UP000261540 UP000242638 UP000007819 UP000002852 UP000007266 UP000221080 UP000265100 UP000261480 UP000028760 UP000261500 UP000261460 UP000005207 UP000265160 UP000265140 UP000007303 UP000240080 UP000002277 UP000265180 UP000002254 UP000002356 UP000233140 UP000028761 UP000233060 UP000233080 UP000261400 UP000001073 UP000008225 UP000005640 UP000050525 UP000000437 UP000261440 UP000261360 UP000261420 UP000261560 UP000018467
Pfam
PF00071 Ras
Interpro
SUPFAM
SSF52540
SSF52540
CDD
ProteinModelPortal
A0A2H1WC25
A0A212ETH2
A0A0L7KXG3
A0A067RMB1
A0A2J7QEG0
A0A194QUR2
+ More
A0A210Q8C3 A0A194PRP1 E1ZVU2 A0A0J7KIL0 A0A151I979 A0A0N7ZDJ1 A0A3M6UZ49 A0A1B6CP69 A0A1B6GBG8 A0A195F604 A0A2B4SR10 A0A195AY94 A0A158NYD1 F4WSZ1 A0A154PLL1 E9JCX4 A0A026VYD3 A0A151IUF2 E2BNQ7 A7SMT0 A0A232F5W3 K7IW40 A0A2I2ZNM3 A0A1B6KRA1 A0A0C9QIF0 T2M3Z8 A0A1S3SJ12 A0A3N0Z1Q8 A0A3P9IVQ8 A0A1W5AF17 A0A224XW91 A0A069DQW3 A0A2K5VLM3 K1PDE3 A0A146Z1E3 G3RGT8 A0A3B3QL17 A0A3P9NFY5 J9KAJ6 M4A7J5 D6WE58 A6YPJ0 U6DEF9 A0A170YS21 A0A3B3QPU6 G9KJR5 W5URF0 A0A2I2YNL4 R4WIM0 A0A3P8PFT1 A0A3B3Z2R0 A0A087XZ46 A0A3B3V562 A0A3B4FXR6 A0A1A7X8I1 A0A1A8JPM6 A0A1A8BQN6 A0A1A8FBV3 A0A1A8VBL2 I3KNT0 A0A3P9D153 A0A3P8ZZF1 A0A1A8PD54 A0A1A8PHU4 A0A2S2NKF0 H3C2P0 A0A2R9CJ64 H2Q6H2 Q4TC69 A0A3P9LTL0 F1PGI1 W5P3L8 A0A2K5YP81 A0A096MUF5 A0A2K5LAB6 A0A2K5HAS3 A0A2R9CLV3 A0A2I3TNY4 A0A3B5AA10 G1QWN6 U3DY75 A0A024RBA9 Q9UL25 A0A151PFL0 A0A2J8W1K2 A0A0B7ANE7 Q08BX0 A0A3B4CWL6 A0A3B4XP57 A0A3B4UPG1 A0A3B3DZ92 A0A2R7VSH7 L8IHK4 A0A3B1JD19
A0A210Q8C3 A0A194PRP1 E1ZVU2 A0A0J7KIL0 A0A151I979 A0A0N7ZDJ1 A0A3M6UZ49 A0A1B6CP69 A0A1B6GBG8 A0A195F604 A0A2B4SR10 A0A195AY94 A0A158NYD1 F4WSZ1 A0A154PLL1 E9JCX4 A0A026VYD3 A0A151IUF2 E2BNQ7 A7SMT0 A0A232F5W3 K7IW40 A0A2I2ZNM3 A0A1B6KRA1 A0A0C9QIF0 T2M3Z8 A0A1S3SJ12 A0A3N0Z1Q8 A0A3P9IVQ8 A0A1W5AF17 A0A224XW91 A0A069DQW3 A0A2K5VLM3 K1PDE3 A0A146Z1E3 G3RGT8 A0A3B3QL17 A0A3P9NFY5 J9KAJ6 M4A7J5 D6WE58 A6YPJ0 U6DEF9 A0A170YS21 A0A3B3QPU6 G9KJR5 W5URF0 A0A2I2YNL4 R4WIM0 A0A3P8PFT1 A0A3B3Z2R0 A0A087XZ46 A0A3B3V562 A0A3B4FXR6 A0A1A7X8I1 A0A1A8JPM6 A0A1A8BQN6 A0A1A8FBV3 A0A1A8VBL2 I3KNT0 A0A3P9D153 A0A3P8ZZF1 A0A1A8PD54 A0A1A8PHU4 A0A2S2NKF0 H3C2P0 A0A2R9CJ64 H2Q6H2 Q4TC69 A0A3P9LTL0 F1PGI1 W5P3L8 A0A2K5YP81 A0A096MUF5 A0A2K5LAB6 A0A2K5HAS3 A0A2R9CLV3 A0A2I3TNY4 A0A3B5AA10 G1QWN6 U3DY75 A0A024RBA9 Q9UL25 A0A151PFL0 A0A2J8W1K2 A0A0B7ANE7 Q08BX0 A0A3B4CWL6 A0A3B4XP57 A0A3B4UPG1 A0A3B3DZ92 A0A2R7VSH7 L8IHK4 A0A3B1JD19
PDB
1YZT
E-value=1.09668e-71,
Score=683
Ontologies
GO
GO:0005525
GO:0003924
GO:0005769
GO:0032482
GO:0006886
GO:1904115
GO:0017157
GO:0019003
GO:0032580
GO:0050775
GO:0008089
GO:0005802
GO:0009898
GO:0098559
GO:0048260
GO:0012506
GO:2000643
GO:0030516
GO:0045202
GO:0070062
GO:0031901
GO:0005768
GO:0005789
GO:0030659
GO:0032154
GO:0005829
GO:0005925
GO:0007264
GO:0003824
GO:0006542
GO:0007186
GO:0016021
GO:0006810
GO:0009072
GO:0007169
PANTHER
Topology
Subcellular location
Endoplasmic reticulum membrane
Colocalizes with ANKRD27 and VAMP7 in neurites (By similarity). In nonpolarized epithelial Caco-2 cells, found in the endoplasmic reticulum; in polarized cells, observed in vesicles in the apical cytoplasm (PubMed:10887961). During mitosis, in mid-telophase, localized in the ingressing cleavage furrow (PubMed:18804435). In late telophase, detected at the opposite poles of the daughter cells, in vesicles at the base of lamellipodia formed by the separating daughter cells (PubMed:18804435). With evidence from 8 publications.
Golgi apparatus Colocalizes with ANKRD27 and VAMP7 in neurites (By similarity). In nonpolarized epithelial Caco-2 cells, found in the endoplasmic reticulum; in polarized cells, observed in vesicles in the apical cytoplasm (PubMed:10887961). During mitosis, in mid-telophase, localized in the ingressing cleavage furrow (PubMed:18804435). In late telophase, detected at the opposite poles of the daughter cells, in vesicles at the base of lamellipodia formed by the separating daughter cells (PubMed:18804435). With evidence from 8 publications.
trans-Golgi network Colocalizes with ANKRD27 and VAMP7 in neurites (By similarity). In nonpolarized epithelial Caco-2 cells, found in the endoplasmic reticulum; in polarized cells, observed in vesicles in the apical cytoplasm (PubMed:10887961). During mitosis, in mid-telophase, localized in the ingressing cleavage furrow (PubMed:18804435). In late telophase, detected at the opposite poles of the daughter cells, in vesicles at the base of lamellipodia formed by the separating daughter cells (PubMed:18804435). With evidence from 8 publications.
Golgi apparatus membrane Colocalizes with ANKRD27 and VAMP7 in neurites (By similarity). In nonpolarized epithelial Caco-2 cells, found in the endoplasmic reticulum; in polarized cells, observed in vesicles in the apical cytoplasm (PubMed:10887961). During mitosis, in mid-telophase, localized in the ingressing cleavage furrow (PubMed:18804435). In late telophase, detected at the opposite poles of the daughter cells, in vesicles at the base of lamellipodia formed by the separating daughter cells (PubMed:18804435). With evidence from 8 publications.
Early endosome membrane Colocalizes with ANKRD27 and VAMP7 in neurites (By similarity). In nonpolarized epithelial Caco-2 cells, found in the endoplasmic reticulum; in polarized cells, observed in vesicles in the apical cytoplasm (PubMed:10887961). During mitosis, in mid-telophase, localized in the ingressing cleavage furrow (PubMed:18804435). In late telophase, detected at the opposite poles of the daughter cells, in vesicles at the base of lamellipodia formed by the separating daughter cells (PubMed:18804435). With evidence from 8 publications.
Cytoplasmic vesicle membrane Colocalizes with ANKRD27 and VAMP7 in neurites (By similarity). In nonpolarized epithelial Caco-2 cells, found in the endoplasmic reticulum; in polarized cells, observed in vesicles in the apical cytoplasm (PubMed:10887961). During mitosis, in mid-telophase, localized in the ingressing cleavage furrow (PubMed:18804435). In late telophase, detected at the opposite poles of the daughter cells, in vesicles at the base of lamellipodia formed by the separating daughter cells (PubMed:18804435). With evidence from 8 publications.
Cleavage furrow Colocalizes with ANKRD27 and VAMP7 in neurites (By similarity). In nonpolarized epithelial Caco-2 cells, found in the endoplasmic reticulum; in polarized cells, observed in vesicles in the apical cytoplasm (PubMed:10887961). During mitosis, in mid-telophase, localized in the ingressing cleavage furrow (PubMed:18804435). In late telophase, detected at the opposite poles of the daughter cells, in vesicles at the base of lamellipodia formed by the separating daughter cells (PubMed:18804435). With evidence from 8 publications.
Golgi apparatus Colocalizes with ANKRD27 and VAMP7 in neurites (By similarity). In nonpolarized epithelial Caco-2 cells, found in the endoplasmic reticulum; in polarized cells, observed in vesicles in the apical cytoplasm (PubMed:10887961). During mitosis, in mid-telophase, localized in the ingressing cleavage furrow (PubMed:18804435). In late telophase, detected at the opposite poles of the daughter cells, in vesicles at the base of lamellipodia formed by the separating daughter cells (PubMed:18804435). With evidence from 8 publications.
trans-Golgi network Colocalizes with ANKRD27 and VAMP7 in neurites (By similarity). In nonpolarized epithelial Caco-2 cells, found in the endoplasmic reticulum; in polarized cells, observed in vesicles in the apical cytoplasm (PubMed:10887961). During mitosis, in mid-telophase, localized in the ingressing cleavage furrow (PubMed:18804435). In late telophase, detected at the opposite poles of the daughter cells, in vesicles at the base of lamellipodia formed by the separating daughter cells (PubMed:18804435). With evidence from 8 publications.
Golgi apparatus membrane Colocalizes with ANKRD27 and VAMP7 in neurites (By similarity). In nonpolarized epithelial Caco-2 cells, found in the endoplasmic reticulum; in polarized cells, observed in vesicles in the apical cytoplasm (PubMed:10887961). During mitosis, in mid-telophase, localized in the ingressing cleavage furrow (PubMed:18804435). In late telophase, detected at the opposite poles of the daughter cells, in vesicles at the base of lamellipodia formed by the separating daughter cells (PubMed:18804435). With evidence from 8 publications.
Early endosome membrane Colocalizes with ANKRD27 and VAMP7 in neurites (By similarity). In nonpolarized epithelial Caco-2 cells, found in the endoplasmic reticulum; in polarized cells, observed in vesicles in the apical cytoplasm (PubMed:10887961). During mitosis, in mid-telophase, localized in the ingressing cleavage furrow (PubMed:18804435). In late telophase, detected at the opposite poles of the daughter cells, in vesicles at the base of lamellipodia formed by the separating daughter cells (PubMed:18804435). With evidence from 8 publications.
Cytoplasmic vesicle membrane Colocalizes with ANKRD27 and VAMP7 in neurites (By similarity). In nonpolarized epithelial Caco-2 cells, found in the endoplasmic reticulum; in polarized cells, observed in vesicles in the apical cytoplasm (PubMed:10887961). During mitosis, in mid-telophase, localized in the ingressing cleavage furrow (PubMed:18804435). In late telophase, detected at the opposite poles of the daughter cells, in vesicles at the base of lamellipodia formed by the separating daughter cells (PubMed:18804435). With evidence from 8 publications.
Cleavage furrow Colocalizes with ANKRD27 and VAMP7 in neurites (By similarity). In nonpolarized epithelial Caco-2 cells, found in the endoplasmic reticulum; in polarized cells, observed in vesicles in the apical cytoplasm (PubMed:10887961). During mitosis, in mid-telophase, localized in the ingressing cleavage furrow (PubMed:18804435). In late telophase, detected at the opposite poles of the daughter cells, in vesicles at the base of lamellipodia formed by the separating daughter cells (PubMed:18804435). With evidence from 8 publications.
Length:
209
Number of predicted TMHs:
0
Exp number of AAs in TMHs:
0.22849
Exp number, first 60 AAs:
0.2276
Total prob of N-in:
0.27900
outside
1 - 209
Population Genetic Test Statistics
Pi
0.490907
Theta
3.553106
Tajima's D
-2.264313
CLR
0
CSRT
0.00154992250387481
Interpretation
Uncertain
