Gene

KWMTBOMO00283

Pre Gene Modal

BGIBMGA000675

Annotation

PREDICTED:_sodium/potassium/calcium_exchanger_3-like_[Papilio_xuthus]

Location

Bomo_Chr1(+):8967993-8975577      View in EpiBrowser

Location in the cell

PlasmaMembrane   Reliability : 4.95

CDS

ATGGAACAAATTAAGGTTGCAAATCTAGCTGTCTTAGTGGGTTTGGTTGCTAGTTTTTATACTGTATCAGCCATCGAGGATTTCAGTTTGTCGAACGACTCTGTTTATTTACGTGTGGAGAGGAATGGGAAAATGATGTACATGACAGAAGAACTAATAAATAAATTAGAACTAGAAGATACGACTTGGCATTGGAAACCATGGCTGAGGACCAGAATTGAAGTCGTTGATAACGTTGCACATGAAGTGGTCTGCGCAACAGGAGATTCCATAGACAGTTTTCCTGATGGTATATTTACAGATGAACAACTCCGTCAAGGTGCCTTCCTTTTGTATGTCGTCTTTGGCATTTACACATTCACACTTTTGGCTATTGTTTGCAATGATTATTTCATTCCTTGTGTTGAACTTATTTGCGAAGACTTGAAGATCCCACAAAACGTAGCAGCAGCTACATTTATGTCTGTCGCGACGTCTTGTCCAGAATTCTTCGTGAACGTGATATCAACCTTTCTAACTGAATCGGATATGGGTATCGGAACTATTGTAGGATCCGCTCTTTTTAATGCTCTCGGAGTAGCTGCTATTGGAGGCCTTGCTGCTATTACACCAATAGCTATCGACATGCGGCCAGTGACAAGAGATGTGCTAATATACATGGTAAATATTAGCGTTCTTGTGGCATTTGTATGGGACGGCCAAATCGATTGGTTTGAGGCGATGGTTCTAGGAATTCTCTATATTTTGTATTTCGTTGTCATGTTTAACAGTATGAAAGCGTTTGTTCTTATTGATAAAATTTGGGCAGCCTGTTGCAAAAAGAATAATGGAGTTACCGCATCTTTGAACGATAACAATGTGTCCGTGGAAGAGGGTATTGATAACAAAGGTTTCAACGACCCCAGTCCTGTTACGAATGGAACCACTATGACGGAGAAGCCAGCTATTGATGAAAAAAATGATGTTGAAGAAACGCTAAATAAAAAAAGTTTGTTTACTTTTCCTTTTCACAAATCAATACTATACAAGATATGGTGGTTTTACATTTGGCCTTTGAAGCTGGTGCTTGGGTTGACTATACCCTCTCCAGTTACTCGAAAAAAGTTATATCCTCTCGCTTTCATAATGTGCATCGTGTGGATTGGAGTGAATTCATACTTTGTGTCTTGGAGTATGACTGTGATAGGACATACCTTCTTTATTCCTGAATCAGTTATGGGGATGACATTTTTAGCATTTGGAGGATGTCTACCAGAAGCGTGCTCGATATTTATTATGTCTAGAAGAGGCGAAGGTGGTATTGGGGTCTCAAATGCACTTGGAGCCAACTCCTTAGCGATTTTGTTTGCTTTGGGCTTACCGTGGTTGATAAGGACAGTTTCGCTGGAAATTCAAGGAGCTGAGAATACCGCAGTACTAATAAACTCAGCAGGTATCGACTTTGTCGTGGGATCTCTTCTTGTAGCTGTTGTCAGTTTATGGATCGTCCTGTTCATTGGAAAATTCACGCTGAGACGTACTGTAGGTATAGTGCTAGGGATACTTTATGTCGTTTTTATCGTTTTCGCTATTCTCGTGGAGTTGGGAATCATTTTCGATCGAAACGTTGAGTTGAGCTCGTGCTGA

Protein

MEQIKVANLAVLVGLVASFYTVSAIEDFSLSNDSVYLRVERNGKMMYMTEELINKLELEDTTWHWKPWLRTRIEVVDNVAHEVVCATGDSIDSFPDGIFTDEQLRQGAFLLYVVFGIYTFTLLAIVCNDYFIPCVELICEDLKIPQNVAAATFMSVATSCPEFFVNVISTFLTESDMGIGTIVGSALFNALGVAAIGGLAAITPIAIDMRPVTRDVLIYMVNISVLVAFVWDGQIDWFEAMVLGILYILYFVVMFNSMKAFVLIDKIWAACCKKNNGVTASLNDNNVSVEEGIDNKGFNDPSPVTNGTTMTEKPAIDEKNDVEETLNKKSLFTFPFHKSILYKIWWFYIWPLKLVLGLTIPSPVTRKKLYPLAFIMCIVWIGVNSYFVSWSMTVIGHTFFIPESVMGMTFLAFGGCLPEACSIFIMSRRGEGGIGVSNALGANSLAILFALGLPWLIRTVSLEIQGAENTAVLINSAGIDFVVGSLLVAVVSLWIVLFIGKFTLRRTVGIVLGILYVVFIVFAILVELGIIFDRNVELSSC

Similarity

Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.
Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.

Uniprot

A0A2A4JT07   A0A2H1WI79   A0A194QVA8   A0A194PTP8   A0A212ETE8   A0A084V9V9   + More
A0A1Y9HFE4   A0A182Q635   A0A1S4F8Z8   Q17BT5   A0A182GKT4   A0A182VNA7   A0A182U315   A0A182MRU6   A0A2C9GR81   A0A182KKG1   A0A1L8DK38   W5JWA6   A0A182Y9M0   A0A182WUK8   A0A182J077   A0A182WE41   V5I898   A0A182FV54   A0A182N2P2   A0A1B0GMI3   A0A182PDA0   A0A084V9W0   A0A182K8I5   Q7PSJ7   A0A1B0GMI4   A0A2C9GR82   Q17BT4   A0A182JHY5   A0A1S4F8P6   D6WM87   A0A182Q6T2   W5JU26   A0A182UQI0   A0A2A3E1A4   A0A1W7R6T4   A0A088AGL8   A0A0T6AXF0   U4UKB9   A0A1I8MJH1   U4UTP4   A0A1B6D9C7   A0A0K8TR74   A0A034W6P0   A0A067R056   B0WBJ4   A0A067RBZ5   A0A1B6M4M0   A0A0K8US07   N6UFJ8   N6THY4   W8BQP8   A0A0K8W873   W8C8K6   A0A0Q9W6E5   A0A0L0BYT5   E2C4F0   A0A310S7P6   A0A0A9XWU9   A0A0A1XSB5   A0A224XMZ1   N6US54   A0A0M9A307   A0A0M3QZN1   A0A023EZI4   A0A2J7QAG0   A0A1W4W1Z0   A0A1W4W1Y6   A0A0L7RBA1   A0A1B6FZ48   A0A1W4WDX3   A0A1B6HL49   A0A021WWX0   A0A1B6JE47   B3MYI6   B4IM40   A0A1W4W1Z1   A0A336LEQ5   A0A1W4WCL5   A0A0J9R6C9   Q7PLW4   A0A1B6KAW2   A0A0N8NZE4   A0A0Q9XHC3   A0A1A9W8U2   A0A0J9R7S8   Q5LJY0   A0A0J9R6Q2   A0A0J9TUA0   A0A1A9XBW7   A0A0J9R6L8   A0A1I8NQJ2   A0A1I8NQJ4   A0A088AGL0  

Pubmed

26354079    22118469    24438588    17510324    26483478    20966253    + More
20920257    23761445    25244985    12364791    18362917    19820115    23537049    25315136    26369729    25348373    24845553    24495485    17994087    26108605    20798317    25401762    26823975    25830018    25474469    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    22936249    26109357    26109356   

EMBL

NWSH01000732    PCG74522.1    ODYU01008830    SOQ52775.1    KQ461108    KPJ09254.1    + More
KQ459594    KPI96129.1    AGBW02012593    OWR44766.1    ATLV01000460    KE523882    KFB34753.1    AXCN02001080    CH477316    EAT43778.1    JXUM01070739    JXUM01070740    JXUM01070741    JXUM01070742    JXUM01070743    KQ562624    KXJ75461.1    AXCM01007828    APCN01001433    GFDF01007347    JAV06737.1    ADMH02000090    ETN67853.1    GALX01005060    JAB63406.1    AJVK01011474    AJVK01011475    KFB34754.1    AAAB01008823    EAA05479.5    AJVK01011476    EAT43779.1    KQ971343    EFA03343.2    ETN67852.1    KZ288460    PBC25477.1    GEHC01000815    JAV46830.1    LJIG01022574    KRT79859.1    KB632364    ERL93567.1    ERL93566.1    GEDC01015015    JAS22283.1    GDAI01000724    JAI16879.1    GAKP01008569    GAKP01008568    JAC50384.1    KK852804    KDR16220.1    DS231879    EDS42433.1    KDR16218.1    GEBQ01009123    JAT30854.1    GDHF01024865    GDHF01023184    JAI27449.1    JAI29130.1    APGK01037673    KB740948    ENN77427.1    ENN77428.1    GAMC01002975    JAC03581.1    GDHF01004911    JAI47403.1    GAMC01002974    JAC03582.1    CH940653    KRF80531.1    JRES01001143    KNC25185.1    GL452462    EFN77187.1    KQ776822    OAD52169.1    GBHO01020256    GBRD01011629    GDHC01019424    JAG23348.1    JAG54195.1    JAP99204.1    GBXI01000396    JAD13896.1    GFTR01006474    JAW09952.1    APGK01018911    KB740085    KB632303    ENN81547.1    ERL91812.1    KQ435752    KOX76187.1    CP012528    ALC49669.1    GBBI01004059    JAC14653.1    NEVH01016330    PNF25571.1    KQ414617    KOC68021.1    GECZ01024111    GECZ01014292    JAS45658.1    JAS55477.1    GECU01032286    JAS75420.1    AE014298    EYR77335.1    GECU01010473    JAS97233.1    CH902632    EDV32680.2    CH480924    EDW43676.1    UFQS01001835    UFQT01001835    SSX12512.1    SSX31955.1    CM002911    KMY91737.1    BT125892    ADV19033.1    EAA46196.2    GEBQ01031390    GEBQ01026499    GEBQ01018163    GEBQ01007137    JAT08587.1    JAT13478.1    JAT21814.1    JAT32840.1    KPU74092.1    CH933812    KRG07049.1    KMY91739.1    BT099540    ACU32624.1    EAL24595.2    KMY91736.1    KMY91740.1    KMY91738.1   

Proteomes

UP000218220    UP000053240    UP000053268    UP000007151    UP000030765    UP000075900    + More
UP000075886    UP000008820    UP000069940    UP000249989    UP000075903    UP000075902    UP000075883    UP000075840    UP000075882    UP000000673    UP000076408    UP000076407    UP000075880    UP000075920    UP000069272    UP000075884    UP000092462    UP000075885    UP000075881    UP000007062    UP000007266    UP000242457    UP000005203    UP000030742    UP000095301    UP000027135    UP000002320    UP000019118    UP000008792    UP000037069    UP000008237    UP000053105    UP000092553    UP000235965    UP000192221    UP000053825    UP000000803    UP000007801    UP000001292    UP000009192    UP000091820    UP000092443    UP000095300   

PRIDE

Q7PLW4    Q5LJY0   

Pfam

PF01699   Na_Ca_ex        + More
PF00858   ASC
PF01510   Amidase_2
PF08449   UAA

Interpro

IPR004481   K/Na/Ca-exchanger        + More
IPR004837   NaCa_Exmemb       
IPR001873   ENaC       
IPR002502   Amidase_domain       
IPR006619   PGRP_domain_met/bac       
IPR036505   Amidase/PGRP_sf       
IPR036259   MFS_trans_sf       
IPR004836   Na_Ca_Ex       
IPR013657   UAA       

SUPFAM

SSF55846   SSF55846        + More
SSF103473   SSF103473       

Gene 3D

3.40.80.10    

CDD

cd06583  PGRP

ProteinModelPortal

A0A2A4JT07   A0A2H1WI79   A0A194QVA8   A0A194PTP8   A0A212ETE8   A0A084V9V9   + More
A0A1Y9HFE4   A0A182Q635   A0A1S4F8Z8   Q17BT5   A0A182GKT4   A0A182VNA7   A0A182U315   A0A182MRU6   A0A2C9GR81   A0A182KKG1   A0A1L8DK38   W5JWA6   A0A182Y9M0   A0A182WUK8   A0A182J077   A0A182WE41   V5I898   A0A182FV54   A0A182N2P2   A0A1B0GMI3   A0A182PDA0   A0A084V9W0   A0A182K8I5   Q7PSJ7   A0A1B0GMI4   A0A2C9GR82   Q17BT4   A0A182JHY5   A0A1S4F8P6   D6WM87   A0A182Q6T2   W5JU26   A0A182UQI0   A0A2A3E1A4   A0A1W7R6T4   A0A088AGL8   A0A0T6AXF0   U4UKB9   A0A1I8MJH1   U4UTP4   A0A1B6D9C7   A0A0K8TR74   A0A034W6P0   A0A067R056   B0WBJ4   A0A067RBZ5   A0A1B6M4M0   A0A0K8US07   N6UFJ8   N6THY4   W8BQP8   A0A0K8W873   W8C8K6   A0A0Q9W6E5   A0A0L0BYT5   E2C4F0   A0A310S7P6   A0A0A9XWU9   A0A0A1XSB5   A0A224XMZ1   N6US54   A0A0M9A307   A0A0M3QZN1   A0A023EZI4   A0A2J7QAG0   A0A1W4W1Z0   A0A1W4W1Y6   A0A0L7RBA1   A0A1B6FZ48   A0A1W4WDX3   A0A1B6HL49   A0A021WWX0   A0A1B6JE47   B3MYI6   B4IM40   A0A1W4W1Z1   A0A336LEQ5   A0A1W4WCL5   A0A0J9R6C9   Q7PLW4   A0A1B6KAW2   A0A0N8NZE4   A0A0Q9XHC3   A0A1A9W8U2   A0A0J9R7S8   Q5LJY0   A0A0J9R6Q2   A0A0J9TUA0   A0A1A9XBW7   A0A0J9R6L8   A0A1I8NQJ2   A0A1I8NQJ4   A0A088AGL0  

PDB

3V5U     E-value=1.95263e-05,     Score=116

KEGG

101742700    no KO assigned | (RefSeq) sodium/potassium/calcium exchanger 4-like

GO

GO:0055085   GO:0016021   GO:0005272   GO:0009253   GO:0008270   GO:0008745   GO:0005887   GO:0005262   GO:0006874   GO:0008273   GO:0070588   GO:0005432   GO:0006814   GO:0016020   GO:0006101   GO:0005506   GO:0009072   GO:0006810   GO:0007169  

PANTHER

PTHR10846  

SignalP

Position:   1 - 24,         Likelihood:  0.682174

 

 

Length:

541

Number of predicted TMHs:

11

Exp number of AAs in TMHs:

236.93128

Exp number, first 60 AAs:

17.77363

Total prob of N-in:

0.93900

POSSIBLE N-term signal

sequence

inside

1  -  6

TMhelix

7  -  25

outside

26  -  105

TMhelix

106  -  128

inside

129  -  148

TMhelix

149  -  171

outside

172  -  180

TMhelix

181  -  203

inside

204  -  215

TMhelix

216  -  238

outside

239  -  241

TMhelix

242  -  264

inside

265  -  368

TMhelix

369  -  390

outside

391  -  404

TMhelix

405  -  427

inside

428  -  433

TMhelix

434  -  456

outside

457  -  475

TMhelix

476  -  498

inside

499  -  509

TMhelix

510  -  532

outside

533  -  541

 

 

Pi

6.417117

Theta

13.849783

Tajima's D

-0.641899

CLR

0.188851

CSRT

0.209589520523974

Interpretation

Uncertain