SGID Silkworm Genome Informatics Database
Gene
KWMTBOMO00274
Pre Gene Modal
BGIBMGA000550
Annotation
hypothetical_protein_KGM_21736_[Danaus_plexippus]
Full name
Mediator of RNA polymerase II transcription subunit 23      
Alternative Name
Mediator complex subunit 23
dSUR2
dTRAP150
Location in the cell
PlasmaMembrane   Reliability : 2.352
 

Sequence

CDS
ATGCTCCAGTGCTTAGCTAGTTTTTTGTATAAAGGTGACCGTCAATCCAAGCGCATGTTCGAGGAAAATATAATCACGGAAATGGCCGATTCGCAAGTCGCCAACATAGTGAATGAAATATTGAAAGTTGAGGCAGTAGAGGAAGCTTTTAGTAGTTTCCTGGTTCACAAACCTGAACAAGAAAATGAGAGACTTTCAATGTATCAAAAGAAGCTATGCAGTATCTTGACAACTCTCAATCCCGATCTCCAAGAGTCCTCTATCCGTCAATATCTTACTTTGACTGCAGTCTTGACAAACAAATACAAAATGAAGCAATTGCTCACATTGTTGGAGAATTTGGTGAATACAAATATCCTTCAAGCTCGGATGTTGTGTGATTGTATTTTGACCAACGAAAAACTTATTTATCAGAATGCTGACTTTTGGATCGAATGCTTTAGTTTAATTAGAAGAATAATAGGAGGCGTTGATTACAAAGGCGTTCGAGAAATTATGAAGGGATGTCGCGAGAAAGCTCATTCATTACCCGTTAGTTTGAATTCGAGTACAATGCCCCAGTTAAAAGCGTTATACAACGTGATTGAATATATTTTTGATCGCAATGCATCCTTGTTACCTGCATATTTTATTGTTACCGAAATTCAAAAAGATTATCCTGATAACAACCATTGGCCACATTGGCAATTAGCAAAACTGTTGACTAGTTTTGTTGAGAGTACTAAGCCTTGCGCTCAAATGGTTTCGATAATCGGTCATTCTAATATGCTCCCTGTTGTCGAGTTTTCTGGATTTGCTGATCATTTAGTGAATCCATGGCGTTTAGATCCCACTACTCTGAAGTTTTCTTTAAAAGGCAACCTGCCATATGATGATGAACTGCTAAAACCACAAATAGGATTAATAAGGCACGTCTTACAGCAGCCTTACTCCAGAGACATGATGTGTTCAATGCTTGGTCTCCAAAAACAACACAAACAGCAATGTATTGCCCTTGAAGATCAACTAGTAGAACTGATGATATTGCCTATGGAAAAAAGTGAACAGGAAAATGATGAAGATGAAATGTCACCAACACATTGGTGTTGGTTGCATCTATCGTCACAAGTTATTTACTTAATATTGATTGGATTCGCTTCTTTCCCCAACATTGTTATGGGCTTACACAATAAACTTGTCGGTCATGACATGAAGAAAGGCCGAGATCATCTTATGTGGGTTCTATTACAATTCATATCTGGAAGCATCCAGCGGCATCCACTTTCGAATTTTATACCCATAATTAAATTACACGAATTATTGTATCCTGAAAAAGATCCGCTACCGGTACCAGATTATTCCAAAGCACATTGTACTCACCAAATGGCGGTTGTATGTATATGGATGCATCTTTTAAAAAAGGCGGAGACTGAACACAAAACTATGACAATGCCGCCAAACTTAAAAGTGCAATACGACTTTCTCCAGCATCTTATGACATCAAATAATATCCCGACTCTGGGCTCTGACTATCGCATTGCGTTGCTTTGTAATGCATATTCAACGAATCAAGAATATTATGCGCGACCTATGGGAATAATAATCGAAACCTTATTTGGAAATCAGAAACCATTGCCCAACGGGAGCACAACCGCTCCCTTGCCCACCGTACCATTGTCGATGTGCATCCTGGACAGTTTGACTTTGCATTGTAAAATGTCTCTTATTCACTCCATAGTGACCCATGTCGCGAAATTAGCACAGAATAAAACAAACATTCCTGGTAACAATATGATGTCTCCGGCACTTGTCGAAACGTATAGCCGACTGTTGGTGTATACTGAAATAGAATCTCTGGGAATTAAAGGGTTTATTAATCAACTTTTGCCTAACGTGTTCAAATCTCATGCGTGGGGTATACTACATGATCTATTAGACATGTTTTCTTATCGGATACATCATGTTCAACCACATTACAGAGTGCAATTATTATCAAACATACATTCTTTAGCAGCCTACCCTCAAGCTAACCAGACGCAACTGCAACTGTGTTTCGAAAGCACTGCTCTTCGCCTTATAACGAGTCTCGGTAGCTCTGGCGTTCAGCTACAGATGTCTCGTGTCGTATCGGAGCCGAAGTCGCTTGTTTCGTCCGAGAGTGAAGAACTTAACAGAGTATTAGTATTGACTCTCGCTCGAGGGATCCACATGGCGGGCGCTGGTAGCGATGGGGCAGCAGTTAAAGAACTTCTCACAACAATAATGACGAACACTCCTCACATGTGGTCGCAGCATACGCTCCAATGCTTTCCACCTGTTCTTGTCGAGTTTTTTAATCAGATTTCGGCGCAAAAGGAAAATAAACAGCTCTTGAAAAAATCGGTAGAAGAGGAGTACCGCAAATGGACATCGATGGCGAACGACAACGATATAATATCACATTTCTCTGTTCCGGGTACACCACTATTTCTGTGCCTATTATGGAAGATGATATTTGAGACCAACCGGATCAACCCTATTGCTTTTAAGATTTTAGAACGCATCGGCGCTAGGGCTTTGTCGGCACATTTGCACTCGTCCTATGTTTGGTGA
Protein
MLQCLASFLYKGDRQSKRMFEENIITEMADSQVANIVNEILKVEAVEEAFSSFLVHKPEQENERLSMYQKKLCSILTTLNPDLQESSIRQYLTLTAVLTNKYKMKQLLTLLENLVNTNILQARMLCDCILTNEKLIYQNADFWIECFSLIRRIIGGVDYKGVREIMKGCREKAHSLPVSLNSSTMPQLKALYNVIEYIFDRNASLLPAYFIVTEIQKDYPDNNHWPHWQLAKLLTSFVESTKPCAQMVSIIGHSNMLPVVEFSGFADHLVNPWRLDPTTLKFSLKGNLPYDDELLKPQIGLIRHVLQQPYSRDMMCSMLGLQKQHKQQCIALEDQLVELMILPMEKSEQENDEDEMSPTHWCWLHLSSQVIYLILIGFASFPNIVMGLHNKLVGHDMKKGRDHLMWVLLQFISGSIQRHPLSNFIPIIKLHELLYPEKDPLPVPDYSKAHCTHQMAVVCIWMHLLKKAETEHKTMTMPPNLKVQYDFLQHLMTSNNIPTLGSDYRIALLCNAYSTNQEYYARPMGIIIETLFGNQKPLPNGSTTAPLPTVPLSMCILDSLTLHCKMSLIHSIVTHVAKLAQNKTNIPGNNMMSPALVETYSRLLVYTEIESLGIKGFINQLLPNVFKSHAWGILHDLLDMFSYRIHHVQPHYRVQLLSNIHSLAAYPQANQTQLQLCFESTALRLITSLGSSGVQLQMSRVVSEPKSLVSSESEELNRVLVLTLARGIHMAGAGSDGAAVKELLTTIMTNTPHMWSQHTLQCFPPVLVEFFNQISAQKENKQLLKKSVEEEYRKWTSMANDNDIISHFSVPGTPLFLCLLWKMIFETNRINPIAFKILERIGARALSAHLHSSYVW

Summary

Description
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity). Required for transcriptional activation in response to heat shock.
Subunit
Component of the Mediator complex.
Component of the Mediator complex (By similarity). Interacts with Hsf.
Similarity
Belongs to the Mediator complex subunit 23 family.
Keywords
Activator   Complete proteome   Nucleus   Reference proteome   Transcription   Transcription regulation   Coiled coil  
Feature
chain  Mediator of RNA polymerase II transcription subunit 23
EMBL
AGBW02011334    OWR46814.1    KQ461108    KPJ09247.1    KQ459594    KPI96136.1    + More
BABH01006967    BABH01006968    BABH01006969    BABH01006970    BABH01006971    NWSH01000884    PCG73712.1    KK852480    KDR22950.1    JTDY01000029    KOB79320.1    ODYU01003957    SOQ43350.1    KK107078    QOIP01000011    EZA60234.1    RLU17149.1    KQ434938    KZC12101.1    GL441512    EFN64710.1    KQ414627    KOC67460.1    KZ288462    PBC25467.1    LBMM01008851    KMQ88585.1    GL762111    EFZ22077.1    KQ435828    KOX71879.1    KQ976725    KYM76531.1    ADTU01016114    ADTU01016115    GL888255    EGI63782.1    KQ978957    KYN27194.1    KQ982813    KYQ50339.1    KQ977622    KYN01310.1    KQ981636    KYN38770.1    KQ769940    OAD52744.1    GEDC01014825    JAS22473.1    GBYB01006314    GBYB01006315    JAG76081.1    JAG76082.1    DS235817    EEB17621.1    GECU01009702    JAS98004.1    ACPB03023227    ACPB03023228    GBBI01002712    JAC16000.1    GEDC01025056    JAS12242.1    KY809857    ATI09806.1    GL447857    EFN85808.1    GBGD01000110    JAC88779.1    GDHC01019314    JAP99314.1    GBHO01008229    JAG35375.1    GBHO01008232    JAG35372.1    AAZX01002897    NEVH01020867    PNF20803.1    NNAY01001424    OXU24023.1    KQ971319    EFA00475.1    AJVK01006587    DS231814    EDS31718.1    GFDL01010256    JAV24789.1    JXUM01019778    JXUM01019779    KQ560554    KXJ81909.1    CH478169    OXU24022.1    ABLF02029119    GGMR01007116    MBY19735.1    GGMS01007657    MBY76860.1    LJIG01022852    KRT78384.1    GGFK01007394    MBW40715.1    ATLV01020273    KE525297    KFB44984.1    AXCM01004515    AXCN02000399    APCN01000069    AAAB01008960    EAA11662.5    ADMH02001390    ETN62683.1    JH431944    GANP01006658    JAB77810.1    GGLE01003472    MBY07598.1    GFTR01008652    JAW07774.1    GFPF01009619    MAA20765.1    GDHF01004151    JAI48163.1    JRES01001578    KNC21836.1    GEDV01005869    JAP82688.1    GAKP01020716    JAC38236.1    GBXI01016042    JAC98249.1    GAMC01018818    JAB87737.1    CM000158    EDW92238.2    LNIX01000003    OXA58541.1    CM000362    EDX08282.1    CM002911    KMY95913.1    CH480824    EDW56859.1    AE013599    BT029934    CH954179    EDV56717.2    CH916367    EDW01153.1    AYCK01008705   
Pfam
PF11573   Med23        + More
PF10250   O-FucT
Interpro
IPR021629   Mediator_Med23        + More
IPR016024   ARM-type_fold       
IPR019378   GDP-Fuc_O-FucTrfase       
SUPFAM
SSF48371   SSF48371       
PDB
6H02     E-value=0,     Score=2147

Ontologies

Topology

Subcellular location
Nucleus  
Length:
856
Number of predicted TMHs:
0
Exp number of AAs in TMHs:
2.47038
Exp number, first 60 AAs:
0
Total prob of N-in:
0.01025
outside
1  -  856
 
 

Population Genetic Test Statistics

Pi
31.604859
Theta
31.917463
Tajima's D
-0.833313
CLR
0.051384
CSRT
0.168391580420979
Interpretation
Uncertain
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