Gene

KWMTBOMO00254  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA000559

Annotation

triosephosphate_isomerase_[Bombyx_mori]

Location

Bomo_Chr1(-):8529615-8532965      View in EpiBrowser

Full name

Triosephosphate isomerase      

Alternative Name

Triose-phosphate isomerase

Location in the cell

Cytoplasmic   Reliability : 3.393

CDS

ATGGGTCGCAAATTTGTTGTTGGAGGTAACTGGAAGATGAATGGTGACAAAAATCAAATCAACGAAATAGTTAATAATCTAAAAAAGGGACCTCTAGATCCTAATGTTGAGGTAATTGTTGGTGTTCCTGCTATTTACCTGTCTTATGTGAAGACTATCATTCCTGATAATGTCGAAGTTGCAGCCCAGAACTGTTGGAAGTCTCCAAAAGGAGCTTTTACTGGTGAAATTTCACCCGCTATGATCAAAGACGTTGGAGTAAATTGGGTTATACTTGGTCATTCTGAAAGAAGAACAATTTTTGGTGAAAAAGATGAACTTGTTGCTGAAAAGGTTGCTCATGCCCTTGAATCTGGCTTGAAAGTCATTGCCTGTATTGGTGAGACTCTCGAAGAGAGAGAATCTGGCAAGACTGAGGAAGTTGTTTTTAGACAATTAAAAGCTTTAGTATCGGCCATTGGTGACAAATGGGAAAATATTGTGCTTGCCTATGAACCTGTATGGGCTATTGGTACAGGCAAGACTGCTACTCCCCAACAGGCTCAAGATGTCCACCATGCTCTTCGTAACTGGTTGTCGGCCAATGTGAGTGGGAGTGTATCTGACGCTGTACGTATTCAGTACGGTGGCTCGGTCACAGCTGCTAATGCTAAGGAGCTTGCATCCTGCAAAGACATTGATGGTTTCTTAGTTGGTGGAGCCAGTCTTAAGCCTGAGTTTGTAGAAATTGTAAATGCTAATCAATAA

Protein

MGRKFVVGGNWKMNGDKNQINEIVNNLKKGPLDPNVEVIVGVPAIYLSYVKTIIPDNVEVAAQNCWKSPKGAFTGEISPAMIKDVGVNWVILGHSERRTIFGEKDELVAEKVAHALESGLKVIACIGETLEERESGKTEEVVFRQLKALVSAIGDKWENIVLAYEPVWAIGTGKTATPQQAQDVHHALRNWLSANVSGSVSDAVRIQYGGSVTAANAKELASCKDIDGFLVGGASLKPEFVEIVNANQ

Catalytic Activity

D-glyceraldehyde 3-phosphate = dihydroxyacetone phosphate

Subunit

Homodimer.

Similarity

Belongs to the triosephosphate isomerase family.

Keywords

Complete proteome   Direct protein sequencing   Gluconeogenesis   Glycolysis   Isomerase   Reference proteome  

Feature

chain  Triosephosphate isomerase

Uniprot

P82204   A0A194PS77   A0A2W1BMP5   Q5XUN5   A0A2H1VCN8   A0A2A4JXG2   + More
S4P3S7   A0A212FLN4   E3UKQ5   D2A042   A0A1Y1NGV6   A0A0L7KX23   Q8MPF2   A0A232EQN8   K7J7M3   J3JWZ9   U4U647   A4ZXC4   N6UJG6   A0A026WB62   I6P143   V9IKD3   A0A1L1ZLV2   A0A084VWK0   A0A182PGM5   A0A0K8TPC5   A0A182FQ32   A0A2M4BXU2   A0A182UTK0   A0A182UA61   A0A182L9S9   Q7PXW5   A0A182MMU2   A0A182YB73   A0A182IWG6   A0A182WSJ2   A0A182HLE4   A0A2M3Z499   A0A2M3ZGK0   A0A2M4A9W5   A0A195DCJ8   A0A182QLI5   V5SJ02   A0A151IGF3   A0A0C9QY89   A0A182VZD4   T1DMV1   A0A182K2M8   U5EUW5   A0A182R608   A0A182NS29   A0A151WFE9   E2AJK8   F4WM74   A0A182SBQ1   A0A1B0ETY1   A0A1I9WLF0   W5J8Q9   E2BX54   A0A0J7KLG9   A0A1I9VT67   A0A1B6LPQ3   A0A154PA23   A0A158P300   A0A195F2F0   E0VJK8   A0A0L7RCW0   Q09KA2   A0A1L8E289   A0A1B6FCS1   A0A2P0XIH0   A0A293MVI9   A0A1B6DQP8   Q17HW3   A0A1B6BWW9   L7UZA7   P30741   A0A1L8E1V1   P55275   A0A2P8XY09   A0A182H0S2   A0A023END4   C4WT45   W8BWJ7   A0A1Z5KWQ3   A0A0C5Q4W3   A2I3Y4   A0A2H8TXV9   A0A3L8DRN9   W8C8K9   T1DII6   A0A0P9ATG2   A0A0K8RFH3   A0A131Y250   A0A0A1WUG1   A0A0A1XKP0   R4UMY9   A0A0P5Z6D0   A0A023FUT8   A0A336LFY4  

EC Number

5.3.1.1

Pubmed

11280994    26354079    28756777    23622113    22118469    18362917    + More
19820115    28004739    26227816    19849721    28648823    20075255    22516182    23537049    24508170    23569222    24438588    26369729    20966253    12364791    14747013    17210077    25244985    20798317    21719571    27538518    20920257    23761445    21347285    20566863    17510324    8429888    7667320    29403074    26483478    24945155    24495485    28528879    25702953    30249741    24330624    17994087    25830018   

EMBL

AY734490    AAU34185.1    KQ459594    KPI96167.1    KZ149961    PZC76329.1    + More
AY736358    AAU84716.2    ODYU01001651    SOQ38172.1    NWSH01000478    PCG76110.1    GAIX01011480    JAA81080.1    AGBW02007730    OWR54655.1    HM449929    ADO33064.1    KQ971338    EFA01748.1    GEZM01002999    JAV96999.1    JTDY01004902    KOB67611.1    AJ496728    CAD43178.1    NNAY01002764    OXU20616.1    AAZX01016602    BT127767    AEE62729.1    KB632166    ERL89334.1    EF493864    EU760983    ABP65286.1    ACE95726.1    APGK01032042    KB740834    ENN78802.1    KK107293    EZA53337.1    JQ771343    AFD93374.1    JR048821    AEY60774.1    KP994676    KP994677    ALG65074.1    ATLV01017623    KE525179    KFB42344.1    GDAI01001607    JAI15996.1    GGFJ01008755    MBW57896.1    AAAB01008987    EAA00928.4    AXCM01001257    APCN01000895    GGFM01002596    MBW23347.1    GGFM01006901    MBW27652.1    GGFK01004234    MBW37555.1    KQ980989    KYN10562.1    AXCN02000266    KF647619    AHB50481.1    KQ977726    KYN00292.1    GBYB01005647    JAG75414.1    GAMD01003425    JAA98165.1    GANO01001272    JAB58599.1    KQ983219    KYQ46533.1    GL440027    EFN66403.1    GL888217    EGI64718.1    AJWK01013578    KU932334    APA33970.1    ADMH02002100    ETN59184.1    GL451202    EFN79773.1    LBMM01005731    KMQ91258.1    KX024698    APA16886.1    GEBQ01014380    JAT25597.1    KQ434856    KZC08702.1    ADTU01001303    KQ981855    KYN34755.1    DS235225    EEB13564.1    KQ414614    KOC68827.1    DQ885469    ABI63547.1    GFDF01001459    JAV12625.1    GECZ01021767    JAS48002.1    KY661336    AVA17423.1    GFWV01019230    MAA43958.1    GEDC01009301    JAS27997.1    CH477245    EAT46226.1    GEDC01031516    JAS05782.1    KC305500    AGC56216.1    L07390    GFDF01001458    JAV12626.1    U23080    PYGN01001178    PSN36887.1    JXUM01022746    KQ560640    KXJ81473.1    JXUM01021307    GAPW01003704    KQ560596    JAC09894.1    KXJ81709.1    ABLF02029934    AK340461    BAH71065.1    GAMC01002963    JAC03593.1    GFJQ02007418    JAV99551.1    KM609492    AJQ30116.1    EF070487    ABM55553.1    GFXV01006935    MBW18740.1    QOIP01000005    RLU23074.1    GAMC01002964    JAC03592.1    GALA01000911    JAA93941.1    CH902617    KPU80615.1    GADI01003891    JAA69917.1    GEFM01002839    JAP72957.1    GBXI01012137    JAD02155.1    GBXI01016352    GBXI01003174    JAC97939.1    JAD11118.1    KC571986    AGM32485.1    GDIP01048324    LRGB01002849    JAM55391.1    KZS06051.1    GBBL01001744    JAC25576.1    UFQS01003368    UFQT01003368    SSX15561.1    SSX34925.1   

Proteomes

UP000005204    UP000053268    UP000218220    UP000007151    UP000007266    UP000037510    + More
UP000215335    UP000002358    UP000030742    UP000019118    UP000053097    UP000030765    UP000075885    UP000069272    UP000075903    UP000075902    UP000075882    UP000007062    UP000075883    UP000076408    UP000075880    UP000076407    UP000075840    UP000078492    UP000075886    UP000078542    UP000075920    UP000075881    UP000075900    UP000075884    UP000075809    UP000000311    UP000007755    UP000075901    UP000092461    UP000000673    UP000008237    UP000036403    UP000076502    UP000005205    UP000078541    UP000009046    UP000053825    UP000008820    UP000245037    UP000069940    UP000249989    UP000007819    UP000279307    UP000007801    UP000076858   

PRIDE

P82204    P30741   

Pfam

PF00121   TIM

Interpro

IPR000652   Triosephosphate_isomerase        + More
IPR035990   TIM_sf       
IPR022896   TrioseP_Isoase_bac/euk       
IPR013785   Aldolase_TIM       
IPR020861   Triosephosphate_isomerase_AS       

SUPFAM

SSF51351   SSF51351       

Gene 3D

3.20.20.70    

CDD

cd00311  TIM

ProteinModelPortal

P82204   A0A194PS77   A0A2W1BMP5   Q5XUN5   A0A2H1VCN8   A0A2A4JXG2   + More
S4P3S7   A0A212FLN4   E3UKQ5   D2A042   A0A1Y1NGV6   A0A0L7KX23   Q8MPF2   A0A232EQN8   K7J7M3   J3JWZ9   U4U647   A4ZXC4   N6UJG6   A0A026WB62   I6P143   V9IKD3   A0A1L1ZLV2   A0A084VWK0   A0A182PGM5   A0A0K8TPC5   A0A182FQ32   A0A2M4BXU2   A0A182UTK0   A0A182UA61   A0A182L9S9   Q7PXW5   A0A182MMU2   A0A182YB73   A0A182IWG6   A0A182WSJ2   A0A182HLE4   A0A2M3Z499   A0A2M3ZGK0   A0A2M4A9W5   A0A195DCJ8   A0A182QLI5   V5SJ02   A0A151IGF3   A0A0C9QY89   A0A182VZD4   T1DMV1   A0A182K2M8   U5EUW5   A0A182R608   A0A182NS29   A0A151WFE9   E2AJK8   F4WM74   A0A182SBQ1   A0A1B0ETY1   A0A1I9WLF0   W5J8Q9   E2BX54   A0A0J7KLG9   A0A1I9VT67   A0A1B6LPQ3   A0A154PA23   A0A158P300   A0A195F2F0   E0VJK8   A0A0L7RCW0   Q09KA2   A0A1L8E289   A0A1B6FCS1   A0A2P0XIH0   A0A293MVI9   A0A1B6DQP8   Q17HW3   A0A1B6BWW9   L7UZA7   P30741   A0A1L8E1V1   P55275   A0A2P8XY09   A0A182H0S2   A0A023END4   C4WT45   W8BWJ7   A0A1Z5KWQ3   A0A0C5Q4W3   A2I3Y4   A0A2H8TXV9   A0A3L8DRN9   W8C8K9   T1DII6   A0A0P9ATG2   A0A0K8RFH3   A0A131Y250   A0A0A1WUG1   A0A0A1XKP0   R4UMY9   A0A0P5Z6D0   A0A023FUT8   A0A336LFY4  

PDB

2I9E     E-value=6.77959e-106,     Score=979

KEGG

100146104    K01803 triosephosphate isomerase (TIM) [EC:5.3.1.1] | (RefSeq) Tpi; triosephosphate isomerase

PATHWAY

00010    Glycolysis / Gluconeogenesis - Bombyx mori (domestic silkworm)
00051    Fructose and mannose metabolism - Bombyx mori (domestic silkworm)
00562    Inositol phosphate metabolism - Bombyx mori (domestic silkworm)
01100    Metabolic pathways - Bombyx mori (domestic silkworm)
01200    Carbon metabolism - Bombyx mori (domestic silkworm)
01230    Biosynthesis of amino acids - Bombyx mori (domestic silkworm)

GO

GO:0006094   GO:0004807   GO:0006096   GO:0046166   GO:0005829   GO:0019563   GO:0008152   GO:0003824   GO:0005506   GO:0009072   GO:0006810   GO:0007169   GO:0016021  

PANTHER

PTHR21139  

Length:

248

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.02389

Exp number, first 60 AAs:

0.02168

Total prob of N-in:

0.04003

outside

1  -  248

 

 

Pi

6.645785

Theta

12.601136

Tajima's D

-1.304235

CLR

0.053457

CSRT

0.0825958702064897

Interpretation

Uncertain