Gene

KWMTBOMO00253

Pre Gene Modal

BGIBMGA000659

Annotation

PREDICTED:_putative_fatty_acyl-CoA_reductase_CG5065_[Bombyx_mori]

Location

Bomo_Chr1(+):8521966-8524244      View in EpiBrowser

Full name

Fatty acyl-CoA reductase      

Location in the cell

PlasmaMembrane   Reliability : 3.731

CDS

ATGTCAAGATTTGTTATTAACATCTTTTTACTTCGGATTACTACGATACTTAGGCTCTGTCCATCATATTCGGAGCCGATGCCAGGTTGGGTTGACAACCTCAATGGACCAGTCGGAGTTATGATTGGAGCTGGCAAAGGAGTAATACGCACTATGCTCTGTGATGGCACCCTAAGCGCTCAAGTAATACCAGTAGATATAGCTATCAATGCAATAATAGCTATAGGAATGATTGAAGGAACAAAAAAAGAAAAATCATTAACAATCCCAGTTTACAATGTAAACATAGGCCACCAAAAACCCATGACTTGGGGGGATGTACTCACCGTCGCGAAAGATTACGGAAGGAAATATCCACTCTCTTGGCCGCTGTGGTATCCAAATGGAGATATAACCACCAACTACACACTTCATGAAATTCGCCGTATATTCTACCACCTTGTACCCGCCTATTGTATAGATTTCCTTCTCTTCCTAATGGGACAGAAACGATTCATGGTCAGAGTACAAGATCGAATCAGTCAGGGTTTACAAGTTTTGCAATATTTCACAATGCGGCCCTGGTCCTTCCCGTGTCCTAACTTTGACAGTATCCCATCAAAACTGAACGAAGAAGAGAGAATTATCTTTAAAGTAGACGTATCTGATGCTGATCCTGCTGAATATATGAAAAGGAGCGTCGAAGGTGGCAGAGTGTTCTGCTTAAAGGAAGATGTTACCAAAATACACCTCAACCGGTCATATCACAATTTCCTCTTTGTAGTGCACTGGGTCTGCAAGATTCTATTTTGGCTTCTTATTTTGTCATTTGTTGCGGCTTATTTTGAACCTGTCAGATATGTACTATCACAGGGCGAACCAGTGGTCAAATATCTTCCATTCGTAGCTTCTGCTGTATTCAAAAACTAA

Protein

MSRFVINIFLLRITTILRLCPSYSEPMPGWVDNLNGPVGVMIGAGKGVIRTMLCDGTLSAQVIPVDIAINAIIAIGMIEGTKKEKSLTIPVYNVNIGHQKPMTWGDVLTVAKDYGRKYPLSWPLWYPNGDITTNYTLHEIRRIFYHLVPAYCIDFLLFLMGQKRFMVRVQDRISQGLQVLQYFTMRPWSFPCPNFDSIPSKLNEEERIIFKVDVSDADPAEYMKRSVEGGRVFCLKEDVTKIHLNRSYHNFLFVVHWVCKILFWLLILSFVAAYFEPVRYVLSQGEPVVKYLPFVASAVFKN

Description

Catalyzes the reduction of fatty acyl-CoA to fatty alcohols.

Catalytic Activity

a long-chain fatty acyl-CoA + 2 H(+) + 2 NADPH = a long-chain primary fatty alcohol + CoA + 2 NADP(+)

Similarity

Belongs to the fatty acyl-CoA reductase family.

Feature

chain  Fatty acyl-CoA reductase

Uniprot

A0A194QW79   A0A1V0M879   A0A2A4JXJ6   I4DIU7   A0A194PRU4   A0A0F6Q2Z9   + More
A0A0F6Q4N3   A0A2W1BU73   A0A291P0P8   A0A0P0DZ32   A0A212FLN3   A0A2H1VBF1   A0A212EPZ8   A0A1V0M881   A0A2H1VDF8   A0A1C9EGN8   A0A2A4K043   A0A0F6Q2P8   A0A291P0Q9   A0A291P0Y2   A0A068FMK7   U5KG45   H9JAM4   A0A194PEZ0   I4DM82   A0A194QKX4   K7JB23   A0A1B0CRT6   A0A088APG8   B4GD23   A0A0L7QMT0   A0A1W4UL71   B4J9N3   A0A0R3NKW5   A0A151XJ37   A0A195FMJ1   B4KQR5   A0A1L8DYA8   A0A0C9RGI8   B4PBX4   F4WVE2   A0A195EP06   D9PTW2   A0A0J9RL31   Q8MMC6   A0A0Q5VPH3   A0A195CPE7   A0A0Q9W5E7   E9ID65   A0A182SVN7   B3MC49   A0A1B0BT19   A0A182REU5   A0A0M4ELA1   Q16GQ4   A0A336KQE3   A0A1A9UZB6   A0A182LXW7   U5EPY7   D9MX50   A0A182VXI1   A0A1S4G1B4   A0A0M9A857   A0A1A9W2D4   A0A1Q3G5B4   A0A182YI99   A0A195BV13   A0A0R3NRV9   W8BBB7   A0A0A1XER0   B4GD25   A0A182P917   W5JHR7   B3NR77   A0A1B0FKH3   A0A182UFP8   A0A182FRU7   A0A084WSE9   A0A182WVP9   A0A182V6X2   A0A182I9C8   Q7QAN3   A0A182K6D3   A0A182QQN9   A0A182NFQ6   A0A034W6Z8   A0A182KXM4   A0A026WTB2   A0A0K8WH42   A0A0K8VVR1   A0A1B6DPR8   A0A0K8UGQ7   A0A0A1WXC2   A0A1W4XHK8   A0A1W4XSR6   A0A0R1DU59   A0A291P0Q5   A0A182JIX2  

EC Number

1.2.1.84

Pubmed

26354079    28349297    22651552    28756777    28986331    26445454    + More
22118469    26385554    24053512    19121390    20075255    17994087    15632085    17550304    21719571    22936249    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    26109357    26109356    18057021    21282665    17510324    20542116    25244985    24495485    25830018    20920257    23761445    24438588    12364791    14747013    17210077    25348373    20966253    24508170    30249741   

EMBL

KQ461108    KPJ09220.1    KU755482    ARD71192.1    NWSH01000478    PCG76112.1    + More
AK401215    BAM17837.1    KQ459594    KPI96166.1    KP237917    AKD01770.1    KP237930    AKD01783.1    KZ149961    PZC76330.1    MF687546    ATJ44472.1    KT261701    ALJ30241.1    AGBW02007730    OWR54654.1    ODYU01001651    SOQ38173.1    AGBW02013342    OWR43572.1    KU755486    ARD71196.1    ODYU01001961    SOQ38879.1    KX778610    AON96651.1    NWSH01000351    PCG77133.1    KP237928    AKD01781.1    MF687538    ATJ44464.1    MF687593    ATJ44519.1    KJ622063    AID66651.1    JX989160    AGR49319.1    BABH01008715    BABH01008716    KQ459606    KPI91588.1    AK402400    BAM19022.1    KQ461198    KPJ06182.1    AAZX01005112    AAZX01005410    AAZX01006950    AAZX01009117    AAZX01017713    AJWK01025254    AJWK01025255    AJWK01025256    CH479181    EDW31561.1    KQ414868    KOC59957.1    CH916367    EDW02540.1    CM000071    KRT01617.1    KQ982080    KYQ60351.1    KQ981490    KYN41164.1    CH933808    EDW09264.2    GFDF01002656    JAV11428.1    GBYB01007475    JAG77242.1    CM000158    EDW92628.2    GL888387    EGI61763.1    KQ978625    KYN29624.1    BT125121    ADM07127.1    CM002911    KMY96477.1    AE013599    BT133449    AAM70799.1    AFH89822.1    CH954179    KQS63158.1    KQ977444    KYN02613.1    CH940648    KRF80268.1    GL762454    EFZ21418.1    CH902619    EDV37236.2    JXJN01019950    JXJN01019951    JXJN01019952    CP012524    ALC42317.1    CH478247    EAT33424.1    UFQS01000822    UFQT01000822    SSX07044.1    SSX27387.1    AXCM01000910    GANO01003516    JAB56355.1    HM536634    ADI87410.1    KQ435728    KOX77819.1    GFDL01000089    JAV34956.1    KQ976401    KYM92422.1    KRT01616.1    GAMC01010608    JAB95947.1    GBXI01004852    JAD09440.1    EDW31563.1    ADMH02001477    ETN62440.1    EDV57096.2    CCAG010016791    CCAG010016792    CCAG010016793    ATLV01026503    ATLV01026504    KE525415    KFB53143.1    APCN01003255    AAAB01008888    EAA08761.5    AXCN02000243    GAKP01009042    JAC49910.1    KK107109    QOIP01000008    EZA59252.1    RLU19596.1    GDHF01001846    JAI50468.1    GDHF01009347    JAI42967.1    GEDC01009624    JAS27674.1    GDHF01026452    JAI25862.1    GBXI01010588    JAD03704.1    KRK00613.1    MF687539    ATJ44465.1   

Proteomes

UP000053240    UP000218220    UP000053268    UP000007151    UP000005204    UP000002358    + More
UP000092461    UP000005203    UP000008744    UP000053825    UP000192221    UP000001070    UP000001819    UP000075809    UP000078541    UP000009192    UP000002282    UP000007755    UP000078492    UP000000803    UP000008711    UP000078542    UP000008792    UP000075901    UP000007801    UP000092460    UP000075900    UP000092553    UP000008820    UP000078200    UP000075883    UP000075920    UP000053105    UP000091820    UP000076408    UP000078540    UP000075885    UP000000673    UP000092444    UP000075902    UP000069272    UP000030765    UP000076407    UP000075903    UP000075840    UP000007062    UP000075881    UP000075886    UP000075884    UP000075882    UP000053097    UP000279307    UP000192223    UP000075880   

PRIDE

H9JAM4    D9PTW2    Q8MMC6   

Pfam

PF03015   Sterile        + More
PF07993   NAD_binding_4

Interpro

IPR036291   NAD(P)-bd_dom_sf        + More
IPR013120   Male_sterile_NAD-bd       
IPR033640   FAR_C       
IPR026055   FAR       

SUPFAM

SSF51735   SSF51735       

CDD

cd09071  FAR_C

ProteinModelPortal

A0A194QW79   A0A1V0M879   A0A2A4JXJ6   I4DIU7   A0A194PRU4   A0A0F6Q2Z9   + More
A0A0F6Q4N3   A0A2W1BU73   A0A291P0P8   A0A0P0DZ32   A0A212FLN3   A0A2H1VBF1   A0A212EPZ8   A0A1V0M881   A0A2H1VDF8   A0A1C9EGN8   A0A2A4K043   A0A0F6Q2P8   A0A291P0Q9   A0A291P0Y2   A0A068FMK7   U5KG45   H9JAM4   A0A194PEZ0   I4DM82   A0A194QKX4   K7JB23   A0A1B0CRT6   A0A088APG8   B4GD23   A0A0L7QMT0   A0A1W4UL71   B4J9N3   A0A0R3NKW5   A0A151XJ37   A0A195FMJ1   B4KQR5   A0A1L8DYA8   A0A0C9RGI8   B4PBX4   F4WVE2   A0A195EP06   D9PTW2   A0A0J9RL31   Q8MMC6   A0A0Q5VPH3   A0A195CPE7   A0A0Q9W5E7   E9ID65   A0A182SVN7   B3MC49   A0A1B0BT19   A0A182REU5   A0A0M4ELA1   Q16GQ4   A0A336KQE3   A0A1A9UZB6   A0A182LXW7   U5EPY7   D9MX50   A0A182VXI1   A0A1S4G1B4   A0A0M9A857   A0A1A9W2D4   A0A1Q3G5B4   A0A182YI99   A0A195BV13   A0A0R3NRV9   W8BBB7   A0A0A1XER0   B4GD25   A0A182P917   W5JHR7   B3NR77   A0A1B0FKH3   A0A182UFP8   A0A182FRU7   A0A084WSE9   A0A182WVP9   A0A182V6X2   A0A182I9C8   Q7QAN3   A0A182K6D3   A0A182QQN9   A0A182NFQ6   A0A034W6Z8   A0A182KXM4   A0A026WTB2   A0A0K8WH42   A0A0K8VVR1   A0A1B6DPR8   A0A0K8UGQ7   A0A0A1WXC2   A0A1W4XHK8   A0A1W4XSR6   A0A0R1DU59   A0A291P0Q5   A0A182JIX2  

KEGG

101741681    K13356 alcohol-forming fatty acyl-CoA reductase [EC:1.2.1.84] | (RefSeq) putative fatty acyl-CoA red

PATHWAY

04146    Peroxisome - Bombyx mori (domestic silkworm)

GO

GO:0006629   GO:0016021   GO:0080019   GO:0102965   GO:0008340   GO:0010025   GO:0005777   GO:0035336  

PANTHER

PTHR11011  

SignalP

Position:   1 - 24,         Likelihood:  0.603154

 

 

Length:

302

Number of predicted TMHs:

2

Exp number of AAs in TMHs:

49.11774

Exp number, first 60 AAs:

1.74006

Total prob of N-in:

0.34085

outside

1  -  142

TMhelix

143  -  160

inside

161  -  250

TMhelix

251  -  273

outside

274  -  302

 

 

Pi

11.219345

Theta

17.760386

Tajima's D

-1.29715

CLR

0.009361

CSRT

0.0901954902254887

Interpretation

Uncertain