Gene

KWMTBOMO00242  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA000564

Annotation

PREDICTED:_endoplasmic_reticulum_mannosyl-oligosaccharide_1?2-alpha-mannosidase_[Amyelois_transitella]

Location

Bomo_Chr1(-):8267524-8273590      View in EpiBrowser

Full name

alpha-1,2-Mannosidase      

Location in the cell

Mitochondrial   Reliability : 1.384

CDS

ATGAGACAGCAAAACTTAGAGACACATCTAAATTTTAATATAAATAATCATACAAATAATGTTAATGATAGAAAATGGGTCACCAATGGAGAGACAGCAATATTACTTAATGATCCAGCAATATCACATACTAAAATTATAAGGAAATGGAATCGTCTATCACGTCTTCAGAGATCCATAGTGTATGCTGTGCTAGTTGTGACTGCAACAGCTCTTTTGTTGCTGTATTTTTCTAAAACTGGTATTGTCATCATTGAGCGAGGCAATGAAGATTCAGTTCAGGAAAAATTAAGAAACACATCTCTAAATGCCAAACCTGCATTGGACAACACAGTTCAAATAAAATATGATCCTACAGTGTATGAGAGGCCTGTTTTTACAGGACCAAAAAATGATCGGCAACGGGCATTGGTGGAAAGTTTTAGACATGCATGGAGAGGGTATAAAGAGCATGCTTGGGGCCATGACAATCTAAAACCAGTCTCTGGTATGGCTTCTGACTGGTTCTCTCTTGGACTTACAATTGTTGACAGTTTGGATACAGCTTACATAATGGGACTAACTGATGTATTTGAGGAAGGCAAGCAATGGATCAAAGAAGAACTAATATTCACAAAAAATAAAGATGTTAATTTCTTTGAAGTCACCATTAGAATACTAGGTGGCTTGTTAACAAATCATTATTTCACTCAAGACCAGCTATTTCTTGATAAAGCTATTGACCTCGGAGACCGTCTCATGGCAGCATTTTCGTCACCATCTGGCATCCCATACTCTGATGTGAACTTGGGAGCTAGAACTGCTCATGCTCCTGAATGGTCACACTACAGCACCACAGCTGAAGTTACTACTGTGCAGTTGGAGTTTAGGCAACTGTCCAGAGCTAGTGGCAACCCTATATTCGAGGAGGCAGCAGCAGCCGTTTCCGAGAAGATTCATCAGCTACCAAAAAAACATGGACTTGTTCCAATATTTATTAATCCGAATACAGGACATTTTCTGCCTCACGCCACCATCACTCTCGGAGCAAGAGGGGATAGTTATTATGAATACCTGCTAAAACAATGGCTCCAGACTGGGAAAACAATCAACTATTTACTGGATGATTATTTAACCGGCATAGAAGGTGTACGTGAATTTTTGGCAAAACGTTCATCACCTAATAAACGATTGTTCATCGGAGAGTTGTCTGCTGGTTCAGAGGCTTTCAATCCGAAAATGGATCATTTGACCTGTTTCTTGCCTGGAACATTGGCCTTAGGTCATTTGAATGGCCTCCCCGACTGGCACATGACAATGGCCGAGGAACTTCTCTACACTTGCTATTTAACTTATGCTGCACATCCAACGTTTTTAGCTCCAGAAATAACACATTTCAATCTCGCGAGCACAACAGATGATATGTATACGAAATCGGCCGATGCTCACAGCTTATTGCGACCGGAATTTATTGAGAGTTTATGGTATATGTATCAAATAACTGGCAATACTACCTATCAAGAATGGGGCTGGCAGATATTCCAGGGCTTCGAAAAATATGCCAAAGTGCCAAACGGCTATTCGTCTCTAACAAACGTGAAATCTGAAAATCCAATACCACGTGACATGATGGAATCTTTCTTTTTGTCAGAAACACTTAAGTACTTGTACTTATTATTGAGTGACGATCGCTTTCTCATCGATTTGAATAAGGAGGGAGAGCGAGCTAAAGTTATCACTGGATGTTAG

Protein

MRQQNLETHLNFNINNHTNNVNDRKWVTNGETAILLNDPAISHTKIIRKWNRLSRLQRSIVYAVLVVTATALLLLYFSKTGIVIIERGNEDSVQEKLRNTSLNAKPALDNTVQIKYDPTVYERPVFTGPKNDRQRALVESFRHAWRGYKEHAWGHDNLKPVSGMASDWFSLGLTIVDSLDTAYIMGLTDVFEEGKQWIKEELIFTKNKDVNFFEVTIRILGGLLTNHYFTQDQLFLDKAIDLGDRLMAAFSSPSGIPYSDVNLGARTAHAPEWSHYSTTAEVTTVQLEFRQLSRASGNPIFEEAAAAVSEKIHQLPKKHGLVPIFINPNTGHFLPHATITLGARGDSYYEYLLKQWLQTGKTINYLLDDYLTGIEGVREFLAKRSSPNKRLFIGELSAGSEAFNPKMDHLTCFLPGTLALGHLNGLPDWHMTMAEELLYTCYLTYAAHPTFLAPEITHFNLASTTDDMYTKSADAHSLLRPEFIESLWYMYQITGNTTYQEWGWQIFQGFEKYAKVPNGYSSLTNVKSENPIPRDMMESFFLSETLKYLYLLLSDDRFLIDLNKEGERAKVITGC

Similarity

Belongs to the glycosyl hydrolase 47 family.

Feature

chain  alpha-1,2-Mannosidase

Uniprot

H9ITI4   A0A2H1VLI6   A0A2A4K4X4   A0A194PRT3   A0A212FDT0   S4PDV8   + More
A0A194QUM3   D6WGJ6   A0A2J7PHK4   A0A067QYZ1   A0A2P8YCE3   A0A1Y1LYG8   A0A1W4X3L7   A0A232FD64   K7IW08   A0A0L7R8Q0   N6T0C4   U4UAU2   A0A0N0BKY8   E0VZD5   V9IM31   E2BM44   A0A087ZXK6   E9G8U4   A0A154P1F5   A0A151IAG3   E2A3G3   A0A195EWI5   A0A195DRV4   F4WV42   A0A026W225   A0A195BTT8   A0A158NNQ2   W5JSD2   A0A2M4BHA7   A0A336M3E3   A0A0J7KUS3   A0A0P4VUB2   A0A0V0G8Z4   A0A336M3F3   A0A182FQ99   A0A023F409   A0A0A9XFA4   A0A182MVJ5   A0A2M4BN05   A0A2M3Z1W2   A0A0P5C3U2   A0A2M3ZG63   A0A1Q3F198   A0A1Q3F1G6   A0A182J968   A0A1B6E7L9   A0A069DZB3   A0A1Q3F1D7   T1IFB6   A0A182SEL3   A0A0P5F668   A0A0P5LVX3   A0A224XM47   A0A0P5KN18   A0A182VQB7   A0A2M4AL54   A0A084WQX2   A0A0P6D9Z0   A0A0P5R2K6   B0W9Q6   A0A182PIY8   A0A182XX80   A0A182RBU6   A0A182HCF3   A0A182WYF5   A0A182VG18   A0A182I8J8   A0A182LAF7   F5HIW5   A0A182GJ00   A0A182TE55   Q7QK05   A0A182N6X4   A0A182QZL9   A0A182KFC0   A0A0P5K4Q7   Q177N4   A0A1S4FCD0   U5ETE3   A0A1J1HVW9   A0A151WUR4   A0A1L8DR46   A0A1L8DQV9   A0A1B6L084   A0A1I8PBE7   I2C0B6   A0A1J1HU32   A0A1I8MB47   A0A1I8MB53   B4M5P2  

EC Number

3.2.1.-

Pubmed

19121390    26354079    22118469    23622113    18362917    19820115    + More
24845553    29403074    28004739    28648823    20075255    23537049    20566863    20798317    21292972    21719571    24508170    30249741    21347285    20920257    23761445    27129103    25474469    25401762    26823975    26334808    24438588    25244985    26483478    20966253    12364791    14747013    17210077    17510324    22561073    25315136    17994087   

EMBL

BABH01006924    ODYU01003221    SOQ41685.1    NWSH01000125    PCG79305.1    KQ459594    + More
KPI96156.1    AGBW02008997    OWR51916.1    GAIX01004792    JAA87768.1    KQ461108    KPJ09228.1    KQ971321    EFA00169.1    NEVH01025136    PNF15809.1    KK853182    KDR10175.1    PYGN01000706    PSN41913.1    GEZM01043996    JAV78592.1    NNAY01000450    OXU28307.1    KQ414631    KOC67257.1    APGK01049519    KB741156    ENN73509.1    KB632169    ERL89428.1    KQ435689    KOX81268.1    DS235851    EEB18741.1    JR052778    AEY61782.1    GL449153    EFN83230.1    GL732535    EFX84035.1    KQ434796    KZC05687.1    KQ978260    KYM95874.1    GL436428    EFN72027.1    KQ981953    KYN32511.1    KQ980530    KYN15650.1    GL888384    EGI61930.1    KK107485    QOIP01000006    EZA50112.1    RLU21984.1    KQ976417    KYM89846.1    ADTU01021714    ADTU01021715    ADMH02000490    ETN66213.1    GGFJ01003299    MBW52440.1    UFQT01000496    SSX24764.1    LBMM01002905    KMQ94202.1    GDKW01000333    JAI56262.1    GECL01001548    JAP04576.1    SSX24765.1    GBBI01003008    JAC15704.1    GBHO01024985    GDHC01016361    JAG18619.1    JAQ02268.1    AXCM01005046    GGFJ01005180    MBW54321.1    GGFM01001677    MBW22428.1    GDIP01180127    JAJ43275.1    GGFM01006771    MBW27522.1    GFDL01013715    JAV21330.1    GFDL01013642    JAV21403.1    GEDC01003356    JAS33942.1    GBGD01000940    JAC87949.1    GFDL01013691    JAV21354.1    ACPB03000966    GDIP01151237    LRGB01002451    JAJ72165.1    KZS07663.1    GDIQ01173461    JAK78264.1    GFTR01007325    JAW09101.1    GDIQ01181952    JAK69773.1    GGFK01008199    MBW41520.1    ATLV01025791    KE525400    KFB52616.1    GDIQ01253833    GDIQ01251147    GDIQ01244134    GDIQ01224645    GDIQ01214301    GDIQ01208157    GDIQ01205401    GDIQ01202443    GDIQ01171914    GDIQ01145825    GDIQ01117785    GDIQ01112434    GDIQ01101627    GDIQ01093484    GDIQ01082089    GDIQ01067800    JAN12648.1    GDIQ01106600    JAL45126.1    DS231865    EDS40375.1    JXUM01127240    KQ567165    KXJ69584.1    APCN01003043    AAAB01008805    EGK96226.1    JXUM01012498    KQ560355    KXJ82872.1    EAA03885.4    AXCN02000311    GDIQ01189600    JAK62125.1    CH477373    EAT42384.1    GANO01002820    JAB57051.1    CVRI01000021    CRK91508.1    KQ982745    KYQ51385.1    GFDF01005274    JAV08810.1    GFDF01005275    JAV08809.1    GEBQ01022922    JAT17055.1    JQ804932    AFJ59949.1    CRK91509.1    CH940652    EDW58968.1   

Proteomes

UP000005204    UP000218220    UP000053268    UP000007151    UP000053240    UP000007266    + More
UP000235965    UP000027135    UP000245037    UP000192223    UP000215335    UP000002358    UP000053825    UP000019118    UP000030742    UP000053105    UP000009046    UP000008237    UP000005203    UP000000305    UP000076502    UP000078542    UP000000311    UP000078541    UP000078492    UP000007755    UP000053097    UP000279307    UP000078540    UP000005205    UP000000673    UP000036403    UP000069272    UP000075883    UP000075880    UP000015103    UP000075901    UP000076858    UP000075920    UP000030765    UP000002320    UP000075885    UP000076408    UP000075900    UP000069940    UP000249989    UP000076407    UP000075903    UP000075840    UP000075882    UP000007062    UP000075902    UP000075884    UP000075886    UP000075881    UP000008820    UP000183832    UP000075809    UP000095300    UP000095301    UP000008792   

PRIDE

H9ITI4   

Pfam

PF01532   Glyco_hydro_47

Interpro

IPR012341   6hp_glycosidase-like_sf        + More
IPR001382   Glyco_hydro_47       
IPR036026   Seven-hairpin_glycosidases       

SUPFAM

SSF48225   SSF48225       

Gene 3D

1.50.10.10    

ProteinModelPortal

H9ITI4   A0A2H1VLI6   A0A2A4K4X4   A0A194PRT3   A0A212FDT0   S4PDV8   + More
A0A194QUM3   D6WGJ6   A0A2J7PHK4   A0A067QYZ1   A0A2P8YCE3   A0A1Y1LYG8   A0A1W4X3L7   A0A232FD64   K7IW08   A0A0L7R8Q0   N6T0C4   U4UAU2   A0A0N0BKY8   E0VZD5   V9IM31   E2BM44   A0A087ZXK6   E9G8U4   A0A154P1F5   A0A151IAG3   E2A3G3   A0A195EWI5   A0A195DRV4   F4WV42   A0A026W225   A0A195BTT8   A0A158NNQ2   W5JSD2   A0A2M4BHA7   A0A336M3E3   A0A0J7KUS3   A0A0P4VUB2   A0A0V0G8Z4   A0A336M3F3   A0A182FQ99   A0A023F409   A0A0A9XFA4   A0A182MVJ5   A0A2M4BN05   A0A2M3Z1W2   A0A0P5C3U2   A0A2M3ZG63   A0A1Q3F198   A0A1Q3F1G6   A0A182J968   A0A1B6E7L9   A0A069DZB3   A0A1Q3F1D7   T1IFB6   A0A182SEL3   A0A0P5F668   A0A0P5LVX3   A0A224XM47   A0A0P5KN18   A0A182VQB7   A0A2M4AL54   A0A084WQX2   A0A0P6D9Z0   A0A0P5R2K6   B0W9Q6   A0A182PIY8   A0A182XX80   A0A182RBU6   A0A182HCF3   A0A182WYF5   A0A182VG18   A0A182I8J8   A0A182LAF7   F5HIW5   A0A182GJ00   A0A182TE55   Q7QK05   A0A182N6X4   A0A182QZL9   A0A182KFC0   A0A0P5K4Q7   Q177N4   A0A1S4FCD0   U5ETE3   A0A1J1HVW9   A0A151WUR4   A0A1L8DR46   A0A1L8DQV9   A0A1B6L084   A0A1I8PBE7   I2C0B6   A0A1J1HU32   A0A1I8MB47   A0A1I8MB53   B4M5P2  

PDB

1FMI     E-value=1.3037e-133,     Score=1222

KEGG

101746534    K01230 mannosyl-oligosaccharide alpha-1,2-mannosidase [EC:3.2.1.113] | (RefSeq) endoplasmic reticulu

PATHWAY

00510    N-Glycan biosynthesis - Bombyx mori (domestic silkworm)
01100    Metabolic pathways - Bombyx mori (domestic silkworm)
04141    Protein processing in endoplasmic reticulum - Bombyx mori (domestic silkworm)

GO

GO:0008152   GO:0005509   GO:0016021   GO:0004571   GO:0016020   GO:0030433   GO:0005783   GO:0006491   GO:0030246   GO:0035010   GO:0004553   GO:0005216   GO:0006811   GO:0006810   GO:0009072   GO:0007169   GO:0003824  

Length:

575

Number of predicted TMHs:

1

Exp number of AAs in TMHs:

20.16918

Exp number, first 60 AAs:

2.31505

Total prob of N-in:

0.99593

inside

1  -  58

TMhelix

59  -  78

outside

79  -  575

 

 

Pi

0.796795

Theta

4.145084

Tajima's D

-2.168107

CLR

0.009041

CSRT

0.00534973251337433

Interpretation

Uncertain