Gene

KWMTBOMO00234

Pre Gene Modal

BGIBMGA000645

Annotation

PREDICTED:_glutamate_receptor_1-like_[Bombyx_mori]

Location

Bomo_Chr1(+):7903031-7939967      View in EpiBrowser

Full name

Glutamate receptor 1      

Alternative Name

Glutamate receptor I
Kainate-selective glutamate receptor

Location in the cell

PlasmaMembrane   Reliability : 3.565

CDS

ATGCTAACTATAAATATTCGGCGTTTGATTGTTCGTGAACATGTGCTGCATACATGTAGCATTGTCTGCAATCAATTCGGACGTGGGGTAATGGCGATGCTGGGTGCTGTAACTCCGGACTCCTTCGACACTCTGCACTCGTATTCCAACACCTTCCAGATGCCGTTCGTGACCCCCTGGTTTCCTGAAAAGGTTATACCACCGTCATCGGGCCTCATCGATTATGCCGTCAGCATGCGACCGGACTACCACCGAGCTGTCATCGACACCATCACCTTCTATGGTTGGAAGAACGTCATATACGTGTATGATTCCCACGACGGTCTGCTTCGCCTCCAGCAACTGTACCAAAGTCTGCAACCGGGCAACGCTACTTTTCGAATTTCTAATGTGAAACGCGTCTCCAACGCAACTGACGTGATCGCATTTCTCGGCTCGATCGAGCGTCTGGATCGCTGGAGCAATAAATACGTTGTACTCGACTCCACAACACAACTCGCTAAAGAAGCTCTAATTTTGCACGTGCGCGACGTAAGGCTCGGGCGCCGGAACTACCATTATTTTCTAAGCGGTCTGGTGATGGACGATCGCTGGGAAAGGGAGGTCACAGAATTCGGAGCTATTAACATAACTGGGTTTAGAGTACTGGATTTTTCGAGAAAAGTCGTAAGAGATTTTATCGATGTTTGGAAGAAGAATTCTATTTCGGCCCAAGCTGCCCTCATGTACGACGCGGTCCAGGTGTTGGTGGACGCCATAGTGCGGCTACTCCGTAAGAAGCCAGATATACTGAGGGGAACGATAAGACGGAATGCCAACGTGAACACAAGCCGCATCATCGACTGCAACCCTAAAGGCAAAATTACACCTTACGAACACGGCGACAAGATATCACGGATGATTAAAAAGACGGAGTTAGATGGGCTGACCGGAAGCCTTCGGTTCAACGAAGAGGGCCATCGTCGCAACTTTACCTTGCAAATCATGGAGCTCACTGTTGATGGTGAAATGGTCAAAATTGCGACGTGGTATGACAACCGCGGACTTGTGCCGGTGGTGCCCAAGCTATCACCATTGTCTCCCCCCGGAACATACGATCGAAACAAAACATACATAGTGTCCACCATAGAAGAGCCCCCATACGTTATGCGGCATAAAGCAGGCGGGCCGGAATCCACGCCTAACGACCCATACAGAGGCTTCTGTGTAGACCTCGCCAAAATGTTATCGGATAAGTTGGAAATCAAATATGACTTACGACTGGTGAAAGACGGAAAGTACGGAAACGACAATCCGAAAATAGTTGGCGGTTGGGACGGGATGGTTGGCGAACTCGTCAGGAAGGAAGTAGATATGGCTATAGCTCCACTCACGATCACACTAGAAAGAGAAACTGTTATTGACTTTAGCAAACCATTTTTGTCGTTCGATGTCAAAACGAAAAAAAATTCATTCAAGGACCCCACTACGATATTCAGTTTTCTTCATCCACTTTCTAAGGAAATATGGCTCTGCATTATATTCAGCTTGTTCGCCGTTAGTGTTGTACTATTTCTGGTATCGAGATTTTCCCCGCACGAATGGCGTTTGATTTCATTCACCGACTCTCAAACTTCGGATCACTCGGAAGTGGCAACAACAAAGACGACCGCGGTCAACGAATTCACCTTCTGGAATTCTATGTGGTTTTCGTTGGGTTCTTTTATGCAGCAGGGCAGCGACATTACGCCGAGATCGATTTCCGGAAGAATTGTAGGATCGGTTTGGTGGTTTTTCGCATTGATCGTTATCTCGTCGTACACTGCCAATTTGGCGTCTTACCTCACCCTGACACGTATATCGGAACCGAGTCAATCATACAACAAATTAGCGACATGCCCTGAGGATACGGCTGGCAATCTAGGAAATTCAATGTTCCAAGAAGGAGGTGAAGGGAATGGCTGGCTTAATTTTATCTTCGATCCTGCTGGTTCTAATAGCGAAAATGATAAAAAGCCCTGTGAAATGTTAGTCACCGTTGCCAGCACTGGGGTGCAGGATTTTGCAGTCGCAATGCCGAAGGGATCCAAATTGCGGGACGGAATCAACCTTGCCCTCCAATCACTTAAAAATGACGGCGAGTTGCAAAAACTCATCCGCAAATGGTTTACTAAAGCAGAGTGTGAAGCTAACCAGGACGTTCAAGGCTCGGAACTGACTTTAGGTCAAGTGGCGGGACTGTTCTACGTCTTGCTGGGTGGACTGGGTCTTGCTTTAGGCGTGGCATTATTGGAATTTTGTCAGCATGGTCGTGCTGAAGCAGCTCGCGCCAATGTCCCACTAGGGGCAGCGTTACGCGCCCGCGCTCAACTTGCTTCGTCTGGAACCAACCGTGACAGGAAGAACAATTCTCAGCGAACCCCACAACGTGATAGCGACCGACTCGGATGGAATGGCGGAGCCTTCACTGGAGTGAGCTACTACAGCCCGGCCACCCAGATCGGTCAGGAGGAGACTTCCCTGCACGCTAGCTTCACGCAAGTCTGA

Protein

MLTINIRRLIVREHVLHTCSIVCNQFGRGVMAMLGAVTPDSFDTLHSYSNTFQMPFVTPWFPEKVIPPSSGLIDYAVSMRPDYHRAVIDTITFYGWKNVIYVYDSHDGLLRLQQLYQSLQPGNATFRISNVKRVSNATDVIAFLGSIERLDRWSNKYVVLDSTTQLAKEALILHVRDVRLGRRNYHYFLSGLVMDDRWEREVTEFGAINITGFRVLDFSRKVVRDFIDVWKKNSISAQAALMYDAVQVLVDAIVRLLRKKPDILRGTIRRNANVNTSRIIDCNPKGKITPYEHGDKISRMIKKTELDGLTGSLRFNEEGHRRNFTLQIMELTVDGEMVKIATWYDNRGLVPVVPKLSPLSPPGTYDRNKTYIVSTIEEPPYVMRHKAGGPESTPNDPYRGFCVDLAKMLSDKLEIKYDLRLVKDGKYGNDNPKIVGGWDGMVGELVRKEVDMAIAPLTITLERETVIDFSKPFLSFDVKTKKNSFKDPTTIFSFLHPLSKEIWLCIIFSLFAVSVVLFLVSRFSPHEWRLISFTDSQTSDHSEVATTKTTAVNEFTFWNSMWFSLGSFMQQGSDITPRSISGRIVGSVWWFFALIVISSYTANLASYLTLTRISEPSQSYNKLATCPEDTAGNLGNSMFQEGGEGNGWLNFIFDPAGSNSENDKKPCEMLVTVASTGVQDFAVAMPKGSKLRDGINLALQSLKNDGELQKLIRKWFTKAECEANQDVQGSELTLGQVAGLFYVLLGGLGLALGVALLEFCQHGRAEAARANVPLGAALRARAQLASSGTNRDRKNNSQRTPQRDSDRLGWNGGAFTGVSYYSPATQIGQEETSLHASFTQV

Description

Receptor for glutamate. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. The postsynaptic actions of Glu are mediated by a variety of receptors that are named according to their selective agonists (By similarity). Forms ligand-gated ion channels which are activated by kainate.

Subunit

Homooligomer.

Similarity

Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.

Keywords

3D-structure   Alternative splicing   Cell junction   Cell membrane   Complete proteome   Glycoprotein   Ion channel   Ion transport   Ligand-gated ion channel   Membrane   Postsynaptic cell membrane   Receptor   Reference proteome   Signal   Synapse   Transmembrane   Transmembrane helix   Transport  

Feature

chain  Glutamate receptor 1
splice variant  In isoform 2.

Uniprot

H9ITR5   A0A0V0J107   A0A2W1BAM5   A0A212EMP7   A0A2H1VKE5   A0A194QVZ8   + More
A0A194Q6H5   A0A194QUJ7   A0A212EMS3   A0A0V0J2T4   A0A2Y9D1L1   D7EHZ7   A0A1S4G7Q1   A0A075T6Z5   A0A1Y1N186   Q7PNT0   A0A3L8DF15   A0A158NFE2   T1HDK9   A0A151JZ81   A0A0C9QXE8   A0A1J1J876   B4KVF4   B4LIB6   A0A1W4UXQ3   B4IXW4   B3M9H9   A0A0R3P8X0   B3NGJ4   A0A3B0KNZ8   A0A336LRY5   B4N2Y2   Q29DR4   B4PJQ8   B4QJS5   Q03445   A0A1L2YXN2   A0A0M4EXY0   E9H8R8   A0A0P6AXH5   A0A0P4ZYN3   A0A0P5BVK8   A0A0P5C8P6   A0A0P6IP12   A0A1L2YXM6   A0A0P5GK06   A0A0C9RSE8   A0A0P5EM22   A0A0P5BI92   A0A151XFV4   A0A0P5BKB1   A0A0P5CZ00   A0A2H8TG59   A0A194Q4Z3   A0A0P5ALF8   A0A0P4ZRV5   A0A0P6DQ48   A0A0P5HB37   A0A0N8A5P0   E0VW33   A0A0N8ADX7   A0A0P5CJN3   A0A0P6HD12   A0A0P5IK63   A0A0N8BR75   A0A0P4YWX8   A0A0P6DJM2   A0A182KPE3   A0A0P5JIQ7   A0A2S2PJV1   A0A182JJ78   A0A0P5BHC1   A0A0M8ZMS8   A0A0P5BKU0   Q170E0   A0A0L7R971   A0A154P0S2   E2BF27   A0A0N7ZQJ7   B4H799   A0A195BCD1   A0A087ZQD0   A0A195E8E3   A0A0K2T188   A0A0P5SK38   E2A6A6   A0A0P4XW61   A0A026WHJ2   T1JZC1   A0A0M4EDF2   A0A2A4ISK2   F4WUH2   A0A336MVV7  

Pubmed

19121390    27006164    28756777    22118469    26354079    18362917    + More
19820115    17510324    25027790    28004739    12364791    30249741    21347285    17994087    15632085    17550304    22936249    1359540    10731132    12537572    21292972    20566863    20966253    20798317    24508170    21719571   

EMBL

BABH01006903    BABH01006904    BABH01006905    GDKB01000027    JAP38469.1    KZ150215    + More
PZC72138.1    AGBW02013810    OWR42780.1    ODYU01003020    SOQ41261.1    KQ461108    KPJ09140.1    KQ459463    KPJ00605.1    KPJ09142.1    OWR42778.1    GDKB01000026    JAP38470.1    DS497669    EFA12935.1    KF768730    AIG51924.1    GEZM01016690    JAV91188.1    AAAB01008960    EAA11672.5    QOIP01000009    RLU18508.1    ADTU01014325    ADTU01014326    ADTU01014327    ADTU01014328    ADTU01014329    ADTU01014330    ADTU01014331    ADTU01014332    ADTU01014333    ADTU01014334    ACPB03000938    ACPB03000939    ACPB03000940    ACPB03000941    ACPB03000942    ACPB03000943    ACPB03000944    ACPB03000945    ACPB03000946    ACPB03000947    KQ981410    KYN41902.1    GBYB01005332    JAG75099.1    CVRI01000075    CRL08584.1    CH933809    EDW18397.1    CH940647    EDW69683.2    CH916366    EDV96485.1    CH902618    EDV41192.1    CH379070    KRT08845.1    CH954178    EDV51160.1    OUUW01000012    SPP87596.1    UFQT01000066    SSX19329.1    CH964062    EDW78721.1    EAL30350.1    CM000159    EDW93657.1    CM000363    CM002912    EDX09466.1    KMY97953.1    M97192    AE014296    BT003218    BT050435    KX016777    APF30026.1    CP012525    ALC43237.1    GL732605    EFX71861.1    GDIP01029649    JAM74066.1    GDIP01209509    JAJ13893.1    GDIP01180016    JAJ43386.1    GDIP01174566    JAJ48836.1    GDIQ01008113    JAN86624.1    KX016772    APF30021.1    GDIQ01241334    JAK10391.1    GBYB01011575    JAG81342.1    GDIP01146122    JAJ77280.1    GDIP01184715    JAJ38687.1    KQ982182    KYQ59168.1    GDIP01183366    JAJ40036.1    GDIP01163482    JAJ59920.1    GFXV01000473    MBW12278.1    KPJ00608.1    GDIP01197266    JAJ26136.1    GDIP01209510    JAJ13892.1    GDIQ01073743    GDIQ01052945    JAN20994.1    GDIQ01230429    JAK21296.1    GDIP01180017    JAJ43385.1    DS235817    EEB17589.1    GDIP01156921    JAJ66481.1    GDIP01174565    JAJ48837.1    GDIQ01021126    JAN73611.1    GDIQ01211392    JAK40333.1    GDIQ01152859    JAK98866.1    GDIP01222360    JAJ01042.1    GDIQ01076542    JAN18195.1    GDIQ01202352    JAK49373.1    GGMR01017110    MBY29729.1    GDIP01184716    JAJ38686.1    KQ436160    KOX67415.1    GDIP01183367    JAJ40035.1    CH477476    EAT40294.1    KQ414627    KOC67420.1    KQ434795    KZC05526.1    GL447910    EFN85705.1    GDIP01222361    JAJ01041.1    CH479217    EDW33705.1    KQ976514    KYM82208.1    KQ979440    KYN21485.1    HACA01001900    CDW19261.1    GDIP01138773    JAL64941.1    GL437123    EFN70991.1    GDIP01235911    JAI87490.1    KK107199    EZA55532.1    CAEY01001120    ALC43621.1    NWSH01007937    PCG62745.1    GL888365    EGI62137.1    UFQT01002179    SSX32863.1   

Proteomes

UP000005204    UP000007151    UP000053240    UP000053268    UP000075884    UP000007266    + More
UP000007062    UP000279307    UP000005205    UP000015103    UP000078541    UP000183832    UP000009192    UP000008792    UP000192221    UP000001070    UP000007801    UP000001819    UP000008711    UP000268350    UP000007798    UP000002282    UP000000304    UP000000803    UP000092553    UP000000305    UP000075809    UP000009046    UP000075882    UP000075880    UP000053105    UP000008820    UP000053825    UP000076502    UP000008237    UP000008744    UP000078540    UP000005203    UP000078492    UP000000311    UP000053097    UP000015104    UP000218220    UP000007755   

PRIDE

H9ITR5    Q03445   

Pfam

PF00497   SBP_bac_3        + More
PF01094   ANF_receptor
PF00060   Lig_chan
PF10613   Lig_chan-Glu_bd

Interpro

IPR001828   ANF_lig-bd_rcpt        + More
IPR001638   Solute-binding_3/MltF_N       
IPR001320   Iontro_rcpt       
IPR019594   Glu/Gly-bd       
IPR028082   Peripla_BP_I       
IPR001508   Iono_rcpt_met       

SUPFAM

SSF53822   SSF53822       

ProteinModelPortal

H9ITR5   A0A0V0J107   A0A2W1BAM5   A0A212EMP7   A0A2H1VKE5   A0A194QVZ8   + More
A0A194Q6H5   A0A194QUJ7   A0A212EMS3   A0A0V0J2T4   A0A2Y9D1L1   D7EHZ7   A0A1S4G7Q1   A0A075T6Z5   A0A1Y1N186   Q7PNT0   A0A3L8DF15   A0A158NFE2   T1HDK9   A0A151JZ81   A0A0C9QXE8   A0A1J1J876   B4KVF4   B4LIB6   A0A1W4UXQ3   B4IXW4   B3M9H9   A0A0R3P8X0   B3NGJ4   A0A3B0KNZ8   A0A336LRY5   B4N2Y2   Q29DR4   B4PJQ8   B4QJS5   Q03445   A0A1L2YXN2   A0A0M4EXY0   E9H8R8   A0A0P6AXH5   A0A0P4ZYN3   A0A0P5BVK8   A0A0P5C8P6   A0A0P6IP12   A0A1L2YXM6   A0A0P5GK06   A0A0C9RSE8   A0A0P5EM22   A0A0P5BI92   A0A151XFV4   A0A0P5BKB1   A0A0P5CZ00   A0A2H8TG59   A0A194Q4Z3   A0A0P5ALF8   A0A0P4ZRV5   A0A0P6DQ48   A0A0P5HB37   A0A0N8A5P0   E0VW33   A0A0N8ADX7   A0A0P5CJN3   A0A0P6HD12   A0A0P5IK63   A0A0N8BR75   A0A0P4YWX8   A0A0P6DJM2   A0A182KPE3   A0A0P5JIQ7   A0A2S2PJV1   A0A182JJ78   A0A0P5BHC1   A0A0M8ZMS8   A0A0P5BKU0   Q170E0   A0A0L7R971   A0A154P0S2   E2BF27   A0A0N7ZQJ7   B4H799   A0A195BCD1   A0A087ZQD0   A0A195E8E3   A0A0K2T188   A0A0P5SK38   E2A6A6   A0A0P4XW61   A0A026WHJ2   T1JZC1   A0A0M4EDF2   A0A2A4ISK2   F4WUH2   A0A336MVV7  

PDB

5IDF     E-value=1.6099e-109,     Score=1016

KEGG

101741118    K05313 glutamate receptor, ionotropic, invertebrate | (RefSeq) glutamate receptor 1-like

GO

GO:0016021   GO:0030054   GO:0045211   GO:0004970   GO:0005886   GO:0004971   GO:0032281   GO:0006811   GO:0015277   GO:0008328   GO:0006812   GO:0005234   GO:0016020   GO:0004872   GO:0005216   GO:0006810   GO:0009072   GO:0007169   GO:0038023  

Subcellular location

  
Cell membrane  
Cell junction  
Synapse  
Postsynaptic cell membrane  

Length:

841

Number of predicted TMHs:

3

Exp number of AAs in TMHs:

66.6874800000002

Exp number, first 60 AAs:

0.05845

Total prob of N-in:

0.00486

outside

1  -  501

TMhelix

502  -  524

inside

525  -  587

TMhelix

588  -  610

outside

611  -  736

TMhelix

737  -  759

inside

760  -  841

 

 

Pi

3.985384

Theta

17.647859

Tajima's D

-2.007148

CLR

0.015592

CSRT

0.0126493675316234

Interpretation

Uncertain