Gene

KWMTBOMO00231

Pre Gene Modal

BGIBMGA000567

Annotation

PREDICTED:_glutamate_receptor_1-like_[Bombyx_mori]

Location

Bomo_Chr1(-):7642389-7716150      View in EpiBrowser

Full name

Glutamate receptor 1      

Alternative Name

Glutamate receptor I
Kainate-selective glutamate receptor

Location in the cell

PlasmaMembrane   Reliability : 2.958

CDS

ATGCACAACCAAAATATAACCGGTCGAAGGTTCGAGCTGCAAGCATATGTGGACGTCATTAACACAGCCGATGCATTCAAGCTTTCACGACTCATATGCAACCAGTTCGCACGAGGCGTGTTCGCTATGCTTGGAGCTGTGACACCGGAATCCTTCGACACGCTGCATTCTTATACAAACACATTCCAAATGCCTTTCGTGACTCCGTGGTTCCCAGAAAAGGTAATTCCACCGTCATCTGGTTTGATTGATCACGCAGTGAGCATGAGACCAGACTATCACAGGGCTATTGTGGATACTATAATTTACTACGGATGGAAAGATATCATCTACATGTACGACTCGCACGATGGATTATTGAGGCTCCAGCAGCTGTACCAATCCATGCAGCCCGGCCGTACCGCGTTCCGAATCTCCCTTGTGAAGCGAATTAATAACGCGTCAGAAGCTTTGGAATTCCTGTTAACATTGGAACAACACGATCGCTGGGGCAACAAGCGCATTGTGCTTGATTGCAATGCGAAAAACGCCAAAAGCATATTAGTCGAGCACGTCCGAAAAGTTCAATTGGGGCGCAGGACATACCACTACATGCTCAGTGGACTAGTGATGGATGATCATTGGGAGAATGAGGTTACCGAGTACGGAGCAGTCAATATTACGGGGTTCCGCATCGTTGACCACTCTAGGAAGATTGTTCGCGATTTCATGGAAGGTTTGCGAAGAATGGACCCCCGGTTCAAGGGGACTATATCGGCAAAAACAGCGCTTATGTACGACGGTGTCCAGGTATTAATGGATGCGCTTAGTAGACTCTGGCGGAAGAAACCGGATGCATTCAGGAATGCACTGCGTCGGGCCGCAGCTGGTCAAATGAACACAACTAAAGTAATTGACTGTAATCCTGGGAAAAACTGGGTGGTGCCTTTCGAGCATGGAGACAAAATCTCAAGGCTGATAAAAAAGACGGACATCGAAGGTCTGACCGGAAATATATCTTTTAATGAGGAAGGTCATCGGTACAATTTCACATTAAATGTCGTTGAGATGACAGTTCAAAGTGCTATGCTGAAGGTAGCAACGTGGTCGGACGTCCGTGGTTTACAGCTTGTCTCGCAGAAACACGTTCAGTTAAAATCACCGGCGTCGTATGACATAAATAGAACGTATATTGTGACAACGGTGCTACAGGAGCCTTACCTAATGCCTAAGCCGTTTGAATTCGGACAGAAAGAGGAACAATTCCACGGATTTTGCAAGGACCTTGCCGATTTAGTGGCGAAAAGACTAGGAATTAAATATGAATTAAGAATAACGAAAGACAATAGAAAAACTGAGGAATTGTTTTCAGAAGGTTCTTCCAGATTAGTCGACGATATAGTCAGAAAGGATGCGGATATAGCAGTGGCTCCTCTGGCTGTGACCCCTGAAAGGGAGCGAGTCTTGGATTTCAGCGAGCCGTTTCTCTCTGTCGATGTCCCGATAACTCACAAGAAACTGCAAAAGCAACTGAAGGATACCTTCAGCTTCCTGAAGCCACTCTCAAAGGAGATATGGCTATGTGTTTTATTTAGTTTTTTTGCTGTGAGCATCGTTCTTTTCTTGGTCTCAAGATTCTCTCCGCGTGAATGGCGATCGATTTCCATATCCGACACACATTTGGATCATCCGATAAGCAGCACGAATGAGATTATACTTCATAATGAATTTAGTATTTGGAATTCGTTCTGGTTTTCTCTCGGCTCTTTTATGCAGCAAGGAAGCGACGTTGTTCCCAAGTCGTTATCTGGAAGAATAGTAGGCACGGTTTGGTGGTTCTTCGCACTTATTCTAGTATGTTCGTACACTGCTAATCTTGCTGCCTATCTAATAGTGGAACGTATAGCAGCGCCAATGCAGTCAATCAGCTATACATCGACCCTGCCGAATATCGAAAATACGCAATTCCCAAGAATTAGTCTGGTAAAAGAACAAAATCCTTATGCTGAAGCTGTCCCTAGCTATGTCTCTAATCGTGAAGGTCAATTCTCCTGCGACACTCCACGCGTCTGCCGATATAAGCATGTATATTACAGTATAGCCACCGCAAAAGGATCGGCACTCAGGGAAGCCATAAACATTGCAATTGTTAATCTGAGGAAGGAAGGTCTATTGACTAAATTGTGGAATAAATGGATTTCAAAAATGAAAAAGCCTGACTGTGATATTGGCAATGATGAGGAATCGTCAATAACGGAGATGACCTTGAGTCAAGTCGCTGGAATATTTTACGTGCTTCTTGGCGGATTGGCTTTGGCTTTAGGTATTGCATTACTGGAATTCTGTCAGCATGGACGAGCTGAAGCTACCCGCGCCAATGTGCCGTTAAGGGCTGCTTTACGTGCGAGAGCAAAATTCGCTTCATCCACAAGGGAACGTAAGACTCCTCCGCAGCGAACGCCACAACGCGACCGCGACCGTCTTGGTTGGAACGGGGCAGCCTTCGCAGGGGTCAGTAAGTACAATGACTTCCTCCTAGGAAGAGAATTGTTGGGACATGCTCACCGAAAAATGTATTAA

Protein

MHNQNITGRRFELQAYVDVINTADAFKLSRLICNQFARGVFAMLGAVTPESFDTLHSYTNTFQMPFVTPWFPEKVIPPSSGLIDHAVSMRPDYHRAIVDTIIYYGWKDIIYMYDSHDGLLRLQQLYQSMQPGRTAFRISLVKRINNASEALEFLLTLEQHDRWGNKRIVLDCNAKNAKSILVEHVRKVQLGRRTYHYMLSGLVMDDHWENEVTEYGAVNITGFRIVDHSRKIVRDFMEGLRRMDPRFKGTISAKTALMYDGVQVLMDALSRLWRKKPDAFRNALRRAAAGQMNTTKVIDCNPGKNWVVPFEHGDKISRLIKKTDIEGLTGNISFNEEGHRYNFTLNVVEMTVQSAMLKVATWSDVRGLQLVSQKHVQLKSPASYDINRTYIVTTVLQEPYLMPKPFEFGQKEEQFHGFCKDLADLVAKRLGIKYELRITKDNRKTEELFSEGSSRLVDDIVRKDADIAVAPLAVTPERERVLDFSEPFLSVDVPITHKKLQKQLKDTFSFLKPLSKEIWLCVLFSFFAVSIVLFLVSRFSPREWRSISISDTHLDHPISSTNEIILHNEFSIWNSFWFSLGSFMQQGSDVVPKSLSGRIVGTVWWFFALILVCSYTANLAAYLIVERIAAPMQSISYTSTLPNIENTQFPRISLVKEQNPYAEAVPSYVSNREGQFSCDTPRVCRYKHVYYSIATAKGSALREAINIAIVNLRKEGLLTKLWNKWISKMKKPDCDIGNDEESSITEMTLSQVAGIFYVLLGGLALALGIALLEFCQHGRAEATRANVPLRAALRARAKFASSTRERKTPPQRTPQRDRDRLGWNGAAFAGVSKYNDFLLGRELLGHAHRKMY

Description

Receptor for glutamate. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. The postsynaptic actions of Glu are mediated by a variety of receptors that are named according to their selective agonists (By similarity). Forms ligand-gated ion channels which are activated by kainate.

Subunit

Homooligomer.

Similarity

Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.

Keywords

3D-structure   Alternative splicing   Cell junction   Cell membrane   Complete proteome   Glycoprotein   Ion channel   Ion transport   Ligand-gated ion channel   Membrane   Postsynaptic cell membrane   Receptor   Reference proteome   Signal   Synapse   Transmembrane   Transmembrane helix   Transport  

Feature

chain  Glutamate receptor 1
splice variant  In isoform 2.

Uniprot

A0A194QUJ7   A0A0V0J2T4   A0A212EMS3   A0A075T6Z5   A0A194Q4Z3   A0A2A4ISK2   + More
D7EHZ7   A0A0L7LBA8   A0A1Y1N186   A0A2Y9D1L1   A0A1S4G7Q1   A0A3L8DF15   Q7PNT0   A0A158NFE2   A0A0V0J107   A0A151JZ81   A0A0C9QXE8   B4N6Y7   A0A1J1J876   A0A2W1BAM5   A0A2H1WMZ6   A0A336LRY5   B4PJQ8   T1HDK9   B3M9H9   Q29DR4   A0A0R3P8X0   B3NGJ4   B4LIB6   B4N2Y2   B4IXW4   A0A1W4UXQ3   Q03445   A0A3B0KNZ8   B4QJS5   B4KVF4   A0A212EMP7   E9H8R8   A0A0M4EXY0   A0A0P6AXH5   A0A0P4ZYN3   A0A0P6IP12   A0A0P5BVK8   A0A0P5C8P6   A0A1L2YXM6   A0A0P5GK06   A0A1L2YXN2   A0A0P5EM22   A0A0P5BKB1   A0A0P4ZRV5   A0A0P5BI92   A0A0P5ALF8   A0A0P6DQ48   A0A0N8A5P0   A0A0P5HB37   B3M9B2   A0A0P6HD12   A0A0P5IK63   A0A0P5CJN3   A0A2H8TG59   A0A0N8BR75   B4KW77   A0A0S0WIE7   B4HKM1   B4QMR2   M9PHV5   A0A0P6DJM2   Q9VSV5   Q9TVG7   B3NFN2   B5DP91   A0A0P5CZ00   A0A2S2RAP8   A0A0P5JIQ7   A0A0P4YWX8   A0A151XFV4   A0A0N8ADX7   A0A0C9RSE8   H9ITR5   B4H799   A0A0P5BKU0   A0A0P5BHC1   A0A2H1VKE5   E0VW33   A0A0N7ZQJ7   A0A2S2PJV1   A0A0K2T188   A0A0P5SK38   A0A182JJ78   A0A0M8ZMS8   A0A154P0S2   A0A0L7R971  

Pubmed

26354079    27006164    22118469    25027790    18362917    19820115    + More
26227816    28004739    17510324    30249741    12364791    21347285    17994087    28756777    17550304    15632085    1359540    10731132    12537572    22936249    21292972    12537568    12537573    12537574    16110336    17569856    17569867    26109357    26109356    19121390    20566863   

EMBL

KQ461108    KPJ09142.1    GDKB01000026    JAP38470.1    AGBW02013810    OWR42778.1    + More
KF768730    AIG51924.1    KQ459463    KPJ00608.1    NWSH01007937    PCG62745.1    DS497669    EFA12935.1    JTDY01001828    KOB72773.1    GEZM01016690    JAV91188.1    QOIP01000009    RLU18508.1    AAAB01008960    EAA11672.5    ADTU01014325    ADTU01014326    ADTU01014327    ADTU01014328    ADTU01014329    ADTU01014330    ADTU01014331    ADTU01014332    ADTU01014333    ADTU01014334    GDKB01000027    JAP38469.1    KQ981410    KYN41902.1    GBYB01005332    JAG75099.1    CH964168    EDW80126.2    CVRI01000075    CRL08584.1    KZ150215    PZC72138.1    ODYU01009720    SOQ54346.1    UFQT01000066    SSX19329.1    CM000159    EDW93657.1    ACPB03000938    ACPB03000939    ACPB03000940    ACPB03000941    ACPB03000942    ACPB03000943    ACPB03000944    ACPB03000945    ACPB03000946    ACPB03000947    CH902618    EDV41192.1    CH379070    EAL30350.1    KRT08845.1    CH954178    EDV51160.1    CH940647    EDW69683.2    CH964062    EDW78721.1    CH916366    EDV96485.1    M97192    AE014296    BT003218    BT050435    OUUW01000012    SPP87596.1    CM000363    CM002912    EDX09466.1    KMY97953.1    CH933809    EDW18397.1    OWR42780.1    GL732605    EFX71861.1    CP012525    ALC43237.1    GDIP01029649    JAM74066.1    GDIP01209509    JAJ13893.1    GDIQ01008113    JAN86624.1    GDIP01180016    JAJ43386.1    GDIP01174566    JAJ48836.1    KX016772    APF30021.1    GDIQ01241334    JAK10391.1    KX016777    APF30026.1    GDIP01146122    JAJ77280.1    GDIP01183366    JAJ40036.1    GDIP01209510    JAJ13892.1    GDIP01184715    JAJ38687.1    GDIP01197266    JAJ26136.1    GDIQ01073743    GDIQ01052945    JAN20994.1    GDIP01180017    JAJ43385.1    GDIQ01230429    JAK21296.1    EDV41125.2    GDIQ01021126    JAN73611.1    GDIQ01211392    JAK40333.1    GDIP01174565    JAJ48837.1    GFXV01000473    MBW12278.1    GDIQ01152859    JAK98866.1    EDW17465.2    ALI30468.1    CH480815    EDW40824.1    EDX09816.1    KMY98577.1    AGB94316.2    GDIQ01076542    JAN18195.1    BT150463    AAF50306.2    AGB94317.1    AJP62085.1    AJ251886    AJ251887    CAB64939.1    CAB64940.1    EDV50574.2    CH379068    EDY73342.2    GDIP01163482    JAJ59920.1    GGMS01017908    MBY87111.1    GDIQ01202352    JAK49373.1    GDIP01222360    JAJ01042.1    KQ982182    KYQ59168.1    GDIP01156921    JAJ66481.1    GBYB01011575    JAG81342.1    BABH01006903    BABH01006904    BABH01006905    CH479217    EDW33705.1    GDIP01183367    JAJ40035.1    GDIP01184716    JAJ38686.1    ODYU01003020    SOQ41261.1    DS235817    EEB17589.1    GDIP01222361    JAJ01041.1    GGMR01017110    MBY29729.1    HACA01001900    CDW19261.1    GDIP01138773    JAL64941.1    KQ436160    KOX67415.1    KQ434795    KZC05526.1    KQ414627    KOC67420.1   

Proteomes

UP000053240    UP000007151    UP000053268    UP000218220    UP000007266    UP000037510    + More
UP000075884    UP000279307    UP000007062    UP000005205    UP000078541    UP000007798    UP000183832    UP000002282    UP000015103    UP000007801    UP000001819    UP000008711    UP000008792    UP000001070    UP000192221    UP000000803    UP000268350    UP000000304    UP000009192    UP000000305    UP000092553    UP000001292    UP000075809    UP000005204    UP000008744    UP000009046    UP000075880    UP000053105    UP000076502    UP000053825   

PRIDE

Q03445    M9PHV5    Q9VSV5    H9ITR5   

Pfam

PF10613   Lig_chan-Glu_bd        + More
PF00060   Lig_chan
PF01094   ANF_receptor
PF00497   SBP_bac_3

Interpro

IPR001508   Iono_rcpt_met        + More
IPR028082   Peripla_BP_I       
IPR019594   Glu/Gly-bd       
IPR001320   Iontro_rcpt       
IPR001828   ANF_lig-bd_rcpt       
IPR001638   Solute-binding_3/MltF_N       

SUPFAM

SSF53822   SSF53822       

ProteinModelPortal

A0A194QUJ7   A0A0V0J2T4   A0A212EMS3   A0A075T6Z5   A0A194Q4Z3   A0A2A4ISK2   + More
D7EHZ7   A0A0L7LBA8   A0A1Y1N186   A0A2Y9D1L1   A0A1S4G7Q1   A0A3L8DF15   Q7PNT0   A0A158NFE2   A0A0V0J107   A0A151JZ81   A0A0C9QXE8   B4N6Y7   A0A1J1J876   A0A2W1BAM5   A0A2H1WMZ6   A0A336LRY5   B4PJQ8   T1HDK9   B3M9H9   Q29DR4   A0A0R3P8X0   B3NGJ4   B4LIB6   B4N2Y2   B4IXW4   A0A1W4UXQ3   Q03445   A0A3B0KNZ8   B4QJS5   B4KVF4   A0A212EMP7   E9H8R8   A0A0M4EXY0   A0A0P6AXH5   A0A0P4ZYN3   A0A0P6IP12   A0A0P5BVK8   A0A0P5C8P6   A0A1L2YXM6   A0A0P5GK06   A0A1L2YXN2   A0A0P5EM22   A0A0P5BKB1   A0A0P4ZRV5   A0A0P5BI92   A0A0P5ALF8   A0A0P6DQ48   A0A0N8A5P0   A0A0P5HB37   B3M9B2   A0A0P6HD12   A0A0P5IK63   A0A0P5CJN3   A0A2H8TG59   A0A0N8BR75   B4KW77   A0A0S0WIE7   B4HKM1   B4QMR2   M9PHV5   A0A0P6DJM2   Q9VSV5   Q9TVG7   B3NFN2   B5DP91   A0A0P5CZ00   A0A2S2RAP8   A0A0P5JIQ7   A0A0P4YWX8   A0A151XFV4   A0A0N8ADX7   A0A0C9RSE8   H9ITR5   B4H799   A0A0P5BKU0   A0A0P5BHC1   A0A2H1VKE5   E0VW33   A0A0N7ZQJ7   A0A2S2PJV1   A0A0K2T188   A0A0P5SK38   A0A182JJ78   A0A0M8ZMS8   A0A154P0S2   A0A0L7R971  

PDB

5IDF     E-value=2.01799e-130,     Score=1196

KEGG

101740977    K05313 glutamate receptor, ionotropic, invertebrate | (RefSeq) glutamate receptor 1-like

GO

GO:0016021   GO:0030054   GO:0045211   GO:0004970   GO:0005886   GO:0004971   GO:0032281   GO:0006811   GO:0015277   GO:0008328   GO:0006812   GO:0005230   GO:0016020   GO:0005234   GO:0004872   GO:0005216   GO:0006810   GO:0009072   GO:0007169   GO:0038023  

Subcellular location

  
Cell membrane  
Cell junction  
Synapse  
Postsynaptic cell membrane  

Length:

852

Number of predicted TMHs:

3

Exp number of AAs in TMHs:

67.9445300000001

Exp number, first 60 AAs:

0.38246

Total prob of N-in:

0.03251

outside

1  -  517

TMhelix

518  -  537

inside

538  -  602

TMhelix

603  -  625

outside

626  -  751

TMhelix

752  -  774

inside

775  -  852

 

 

Pi

26.125452

Theta

21.878473

Tajima's D

-1.478147

CLR

0.046898

CSRT

0.0610969451527424

Interpretation

Uncertain