Gene

KWMTBOMO00230

Pre Gene Modal

BGIBMGA000568

Annotation

GABA-gated_chloride_channel_[Bombyx_mori]

Location

Bomo_Chr1(-):7573986-7602007      View in EpiBrowser

Location in the cell

PlasmaMembrane   Reliability : 4.063

CDS

ATGTACGTGCTCTCCATCAGCTCTCTGTCTGAAGTGAAAATGGACTTCACGTTGGACTTTTACTTCAGACAGTTTTGGACCGATCCGCGATTGGCGTACAAAAAAAGGACAGGAGTTGAAACGTTGTCGGTTGGCTCCGAATTCATAAAGAACATATGGGTGCCCGACACATTCTTTGTGAACGAAAAACAGTCTTATTTCCATATAGCTACGACAAGTAACGAATTTATACGTATACATTACTCTGGCTCAATAACTAGAAGTATAAGATTGACTATTACTGCGTCTTGTCCAATGAATCTGCAATACTTTCCAATGGATCGTCAATTATGCCATATAGAAATAGAAAGTTTCGGCTACACCATGCGGGACATCCGATACAAATGGAACGAGGGGCCCAACTCTGTGGGTGTTTCCAGCGAGGTGTCGCTACCGCAGTTCAAAGTCCTGGGTCACCGCCAACGAGCTATGGAGATCTCCCTCACAACAGGAAATTATTCAAGATTAGCATGTGAAATACAATTTGTGCGCTCTATGGGCTACTATCTAATCCAAATTTACATTCCATCGGGACTCATCGTGATCATATCCTGGGTGTCGTTTTGGTTGAACCGTAACGCCACTCCGGCTCGAGTGGCTCTCGGCGTCACCACTGTGCTGACAATGACAACGCTTATGTCATCGACGAACGCTGCCCTACCAAAAATTTCATACGTAAAATCAATTGACGTCTACTTAGGAACGTGTTTCGTAATGGTCTTCGCGAGTCTTTTAGAATACGCAACTGTCGGATATATGGCTAAGAGAATACAAATGAGGAAACAGCGATTTGTGGCTATACAGAAAATTGCCTCGGAGAAGAAACTTCCAGAATGCCCTCCAGTCGGCGATCCACACACTTTATCGAAGATGAATACTTTAAGCAGATGTCCTCCTAGCAGACCATCTGAAGTCCGTTTTAAAGTTCACGATCCGAAGGCGCATTCCAAAGGCGGTACTTTGGAGAACACCATTAACGGAGGAAGAGGGGGAGCAGACGAAGAAAATCCAGGTCCCCATCCAATACATCCAGGAAAGGATATTAGCAAACTACTGGGAATGACGCCATCAGACATCGACAAATATTCCCGTATAGTTTTCCCGGTTTGCTTCGTTTGTTTTAATCTTATGTATTGGATTATATACCTTCATGTTTCGGACGTCGTGGCTAACGATCTGGTTCTTCTGGAAGAAGATAAATAG

Protein

MYVLSISSLSEVKMDFTLDFYFRQFWTDPRLAYKKRTGVETLSVGSEFIKNIWVPDTFFVNEKQSYFHIATTSNEFIRIHYSGSITRSIRLTITASCPMNLQYFPMDRQLCHIEIESFGYTMRDIRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGVTTVLTMTTLMSSTNAALPKISYVKSIDVYLGTCFVMVFASLLEYATVGYMAKRIQMRKQRFVAIQKIASEKKLPECPPVGDPHTLSKMNTLSRCPPSRPSEVRFKVHDPKAHSKGGTLENTINGGRGGADEENPGPHPIHPGKDISKLLGMTPSDIDKYSRIVFPVCFVCFNLMYWIIYLHVSDVVANDLVLLEEDK

Similarity

Belongs to the ligand-gated ion channel (TC 1.A.9) family.

Uniprot

U3TMA1   A5A2M7   E0X9H7   A0A0U5ACA3   E0X9I5   A0A1Q2T844   + More
A0A2W1BQH7   E0X9H9   A0A2S0DGE1   O18471   A0A2A4JL08   A0A3G1J4Z2   E0X9H8   C0L7I5   C0L955   C0L7I4   A1Z0K6   A3FBG6   C0L956   A9LYI3   A0A212EMT2   E0X9I4   E0X9I2   A0A2H1VGT8   V9Z984   V9ZCF2   Q9XZW0   G8IIS8   G8IIR9   E2IKR3   A5JJ42   O18468   H9JVX7   A0A1W4WE55   M9Z6B1   H3JU08   E0X9I3   E0X9I1   A0A168SJQ0   A0A1W4W3J7   A0A2J7QNV0   A0A1W4WF43   A0A1Q2T857   A0A1Q2T841   A0A168SJP2   A0A2H1WJ59   Q0GQR7   A0A1W4WE60   A0A2A4JF95   A8DMU0   A0A2J7QNV2   A0A087Z8M8   A0A1Q2T839   A0A0B5EEN9   A0A1I8JSK2   A0A168SJJ0   A8DMU1   A0A2H1VH64   A0A2J7QNU9   A0A182XM21   A0A182URJ2   A0A2J7QNV9   A0A1Y9GKS7   A7UU05   A0A182J2V0   A0A1Y9IVD6   A0A1B6DGU4   A0A2A4JFC5   A0A1Y9HEH3   B4LHG7   A0A212EMQ5   A0A2H4WAU8   A0A1Y9H213   A0A1I9VT68   A0A2J7QNV6   A0A1W4W3K5   E0X9I0   A0A0Q9WHF3   A0A182QGF5   A0A0Q9WTB8   A0A0A9WSU0   A0A1I8QEJ2   K7ZRK2   A0A158NFE0   A0A1Q2T843   A0A1W4WFF3   A0A0M4EK86   A0A1W4W3L2   K7ILR9   A0A0A9Y8T5   A0A1X9PRB2   F5C3U5   A0A0K8TDA0   A0A0K8STF5   X5C002   A0A0Q9WH84   A0A1I8QEE6   X5BIT8   A0A1I8QEF2   C0L7I7  

Pubmed

20924418    28756777    29408355    20513056    22118469    24365472    + More
10212398    23909412    19121390    27288983    16902773    17880682    18362917    19820115    20920257    12364791    14747013    17210077    17994087    29183375    26296809    25401762    23156177    21347285    20075255    21501685    18057021   

EMBL

AB847423    BAN92442.1    EF521821    ABP96889.1    GQ890661    ADM88006.1    + More
AB278155    BAT57340.1    GQ890669    ADM88014.1    LC171477    BAW87784.1    KZ149977    PZC75884.1    GQ890663    ADM88008.1    KX856969    ASY91961.1    AF006192    AAB62572.1    NWSH01001075    PCG72737.1    KX856966    ASY91958.1    GQ890662    ADM88007.1    FJ665608    ACN52598.1    FJ668709    ACN53550.1    FJ665607    ACN52597.1    EF156251    ABL86443.1    EF368369    ABN13426.1    ACN53549.1    EU273945    ABX47168.1    AGBW02013810    OWR42777.1    GQ890668    ADM88013.1    GQ890666    ADM88011.1    ODYU01002299    SOQ39612.1    KF881791    AHE41088.1    KF881790    AHE41087.1    AJ224513    CAB41615.1    JN794059    AER59668.1    JN792582    AER59667.1    HM566200    KX856970    ADK74004.1    ASY91962.1    EF535530    ABQ45398.1    AF006189    AAB62563.1    BABH01040612    KC841916    AGK30293.1    AB617631    BAL63029.1    GQ890667    ADM88012.1    GQ890665    ADM88010.1    KU201323    ANC68178.1    NEVH01012562    PNF30265.1    LC171476    BAW87783.1    LC171474    BAW87781.1    KU201322    ANC68177.1    ODYU01009008    SOQ53088.1    DQ667182    ABG75734.1    NWSH01001799    PCG70103.1    EF545117    KQ972204    ABU63595.1    KYB24596.1    PNF30267.1    LC171472    BAW87779.1    KJ485710    AJE68941.1    KU201321    ANC68176.1    EF545118    ABU63596.1    KYB24597.1    SOQ39604.1    PNF30264.1    PNF30268.1    APCN01000072    APCN01000073    AAAB01008960    EDO63781.1    GEDC01012391    JAS24907.1    PCG70102.1    CH940647    EDW68497.2    OWR42773.1    MG190358    AUC64171.1    KX431144    APA16887.1    PNF30266.1    GQ890664    ADM88009.1    KRF83882.1    AXCN02000404    KRF83883.1    GBHO01032740    JAG10864.1    AB697765    BAM66322.1    ADTU01014314    ADTU01014315    ADTU01014316    ADTU01014317    ADTU01014318    ADTU01014319    ADTU01014320    ADTU01014321    LC171473    BAW87780.1    CP012525    ALC43610.1    GBHO01014122    JAG29482.1    KY072798    ARO86294.1    JF460792    AEB60992.1    GBRD01002284    JAG63537.1    GBRD01009258    JAG56563.1    KJ174465    AHW29555.1    KRF83878.1    KRF83879.1    KRF83880.1    KRF83881.1    KJ174466    AHW29556.1    FJ665610    ACN52600.1   

Proteomes

UP000218220    UP000007151    UP000005204    UP000192223    UP000235965    UP000007266    + More
UP000069272    UP000076407    UP000075903    UP000075840    UP000007062    UP000075880    UP000075920    UP000075900    UP000008792    UP000075884    UP000075886    UP000095300    UP000005205    UP000092553    UP000002358   

PRIDE

U3TMA1    A5A2M7    E0X9H7    E0X9I5    E0X9H9    E0X9H8    + More
E0X9I4    E0X9I2    H9JVX7    E0X9I3    E0X9I1    E0X9I0   

Pfam

PF02932   Neur_chan_memb        + More
PF02931   Neur_chan_LBD

Interpro

IPR036719   Neuro-gated_channel_TM_sf        + More
IPR002289   GABAAb_rcpt       
IPR036734   Neur_chan_lig-bd_sf       
IPR006029   Neurotrans-gated_channel_TM       
IPR006028   GABAA/Glycine_rcpt       
IPR006202   Neur_chan_lig-bd       
IPR006201   Neur_channel       
IPR018000   Neurotransmitter_ion_chnl_CS       

SUPFAM

SSF63712   SSF63712        + More
SSF90112   SSF90112       

Gene 3D

2.70.170.10    

ProteinModelPortal

U3TMA1   A5A2M7   E0X9H7   A0A0U5ACA3   E0X9I5   A0A1Q2T844   + More
A0A2W1BQH7   E0X9H9   A0A2S0DGE1   O18471   A0A2A4JL08   A0A3G1J4Z2   E0X9H8   C0L7I5   C0L955   C0L7I4   A1Z0K6   A3FBG6   C0L956   A9LYI3   A0A212EMT2   E0X9I4   E0X9I2   A0A2H1VGT8   V9Z984   V9ZCF2   Q9XZW0   G8IIS8   G8IIR9   E2IKR3   A5JJ42   O18468   H9JVX7   A0A1W4WE55   M9Z6B1   H3JU08   E0X9I3   E0X9I1   A0A168SJQ0   A0A1W4W3J7   A0A2J7QNV0   A0A1W4WF43   A0A1Q2T857   A0A1Q2T841   A0A168SJP2   A0A2H1WJ59   Q0GQR7   A0A1W4WE60   A0A2A4JF95   A8DMU0   A0A2J7QNV2   A0A087Z8M8   A0A1Q2T839   A0A0B5EEN9   A0A1I8JSK2   A0A168SJJ0   A8DMU1   A0A2H1VH64   A0A2J7QNU9   A0A182XM21   A0A182URJ2   A0A2J7QNV9   A0A1Y9GKS7   A7UU05   A0A182J2V0   A0A1Y9IVD6   A0A1B6DGU4   A0A2A4JFC5   A0A1Y9HEH3   B4LHG7   A0A212EMQ5   A0A2H4WAU8   A0A1Y9H213   A0A1I9VT68   A0A2J7QNV6   A0A1W4W3K5   E0X9I0   A0A0Q9WHF3   A0A182QGF5   A0A0Q9WTB8   A0A0A9WSU0   A0A1I8QEJ2   K7ZRK2   A0A158NFE0   A0A1Q2T843   A0A1W4WFF3   A0A0M4EK86   A0A1W4W3L2   K7ILR9   A0A0A9Y8T5   A0A1X9PRB2   F5C3U5   A0A0K8TDA0   A0A0K8STF5   X5C002   A0A0Q9WH84   A0A1I8QEE6   X5BIT8   A0A1I8QEF2   C0L7I7  

PDB

6I53     E-value=1.01575e-70,     Score=678

KEGG

100101200    K05181 gamma-aminobutyric acid receptor subunit beta | (RefSeq) rdl1, Rdl; GABA-gated chlorine chann

PATHWAY

04080    Neuroactive ligand-receptor interaction - Bombyx mori (domestic silkworm)

GO

GO:0005230   GO:0016021   GO:0004890   GO:0005886   GO:0006811   GO:0004888   GO:0034220   GO:0007268   GO:0050877   GO:0007165   GO:0042391   GO:0043005   GO:0005887   GO:0045202   GO:0005216   GO:0016020   GO:0006810   GO:0009072   GO:0007169  

PANTHER

PTHR18945  

Length:

413

Number of predicted TMHs:

4

Exp number of AAs in TMHs:

87.64168

Exp number, first 60 AAs:

0.00114

Total prob of N-in:

0.00364

outside

1  -  180

TMhelix

181  -  203

inside

204  -  211

TMhelix

212  -  234

outside

235  -  243

TMhelix

244  -  266

inside

267  -  376

TMhelix

377  -  399

outside

400  -  413

 

 

Pi

29.193941

Theta

24.343145

Tajima's D

-0.640341

CLR

0.035439

CSRT

0.207839608019599

Interpretation

Uncertain