Gene

KWMTBOMO00226

Pre Gene Modal

BGIBMGA000641

Annotation

ionotropic_GABA-aminobutyric_acid_receptor_RDL2_precursor_[Bombyx_mori]

Location

Bomo_Chr1(+):7484958-7490369      View in EpiBrowser

Location in the cell

PlasmaMembrane   Reliability : 4.687

CDS

ATGTTTGGCGATGTCAATATCTCGGCCATTCTGGATTCCCTGAGCGTTAGCTACGACAAGAGAGTTCGACCAAACTACGGAGGACCACCCGTGGATGTGGGAGTTACCATGTACGTGCTCTCCATCAGCTCTCTGTCTGAAGTGAAAATGGATTTCACACTGGATTTCTACTTTAGACAGTTCTGGACAGATCCGAGGCTTGCTTACAAAAAACGGACCGGAGTTGAGACCCTCTCTGTCGGATCTGAATTTATTAGGAACATATGGGTACCTGACACGTTCTTTGTGAATGAAAAACAATCGTATTTCCATATTGCGACTACTAGTAACGAATTTATTCGTATTCATCATTCTGGATCTATTACTCGAAGCATAAGACTGACCATTACTGCATCTTGTCCTATGGATCTTCAGTACTTTCCAATGGATCGTCAATTATGCAACATTGAAATCGAAAGCTTTGGGTACACCATGCGGGACATCCGTTACAAGTGGAACGAGGGACCCAATTCAGTGGGTGTTTCAAGCGAAGTATCACTGCCACAATTCAAGGTGTTGGGCCACCGTCAGCGAGCAATGGAGATTTCTCTCACGACAGGAAACTATTCGCGGCTTGCCTGCGAAATCCAATTCGTACGCTCAATGGGATACTATTTGATCCAAATTTACATTCCGTCTGGGCTTATCGTTATAATATCGTGGGTATCCTTTTGGTTAAATCGAAACGCTACACCAGCTAGAGTTTCGTTGGGTGTAACAACTGTGCTGACGATGACCACGCTTATGTCTTCGACGAATGCTGCTTTGCCGAAAATATCTTACGTCAAGTCTATTGATGTGTACCTGGGTACCTGCTTCGTGATGGTCTTCGCAAGTTTACTAGAATATGCTACCGTCGGATACATGGCTAAACGAATCCAGATGCGTAAACAACGATTCACTGCTGTGCAAAAGATGGCTGTCGAAAAGAAGATTCAAATCGATGGCCCCCCTGGGCCATCAGAGCCCTTACCTCCACCACGTACTAGCACGCTGTCACGACCTCTACCACCTAGCCGATCTTCGGAAGGAAGATTTAAGGCACATGACTCAAAATCTTATTCTAAGGGTAGCACCCTGGAGAATACTATTAATGGAGCAAGAGCAGCCGTACCTGGACCCGCACCGCAGCCCGACGAAGAAGCAGGAGGACAACCCCAATTGATTCCATCTAAGGGTATTAACAAACTACTGGGCACAACTCCTTCGGATATCGACAAATACTCTCGCATCGTGTTCCCGGTCTGCTTCGTCTGCTTCAATTTGATGTACTGGATAATTTACTTGCATGTCTCCGATGTTGTTGCTGATGACTTGGTACTCCTTGGCGAAGAGAATTGA

Protein

MFGDVNISAILDSLSVSYDKRVRPNYGGPPVDVGVTMYVLSISSLSEVKMDFTLDFYFRQFWTDPRLAYKKRTGVETLSVGSEFIRNIWVPDTFFVNEKQSYFHIATTSNEFIRIHHSGSITRSIRLTITASCPMDLQYFPMDRQLCNIEIESFGYTMRDIRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVSLGVTTVLTMTTLMSSTNAALPKISYVKSIDVYLGTCFVMVFASLLEYATVGYMAKRIQMRKQRFTAVQKMAVEKKIQIDGPPGPSEPLPPPRTSTLSRPLPPSRSSEGRFKAHDSKSYSKGSTLENTINGARAAVPGPAPQPDEEAGGQPQLIPSKGINKLLGTTPSDIDKYSRIVFPVCFVCFNLMYWIIYLHVSDVVADDLVLLGEEN

Similarity

Belongs to the ligand-gated ion channel (TC 1.A.9) family.

Uniprot

E0X9I0   Q9XZW0   G8IIS8   O18468   A5JJ42   E2IKR3   + More
G8IIR9   A0A2H1VH64   A0A212EMQ5   A0A1Q2T844   A0A3G1J4Z2   A0A0U5ACA3   E0X9H7   U3TMA1   V9ZCF2   A0A2S0DGE1   O18471   E0X9I5   A5A2M7   V9Z984   A0A1W4WE55   A0A1W4W3J7   A0A1Q2T839   A0A1Q2T841   C0L7I5   C0L7I7   A0A1W4WF43   A0A1W4WE60   A8DMU0   A9LYI3   B4LHG7   A0A0Q9WHF3   C0L7I4   A8DMU1   C0L957   A0A1I8QEE6   H3JU08   A0A1I8QEJ2   A1Z0K6   A3FBG6   A0A0Q9WTB8   A0A168SJP2   C0L955   X5BIT8   A0A0B5EEN9   M9Z6B1   A0A168SJJ0   B4KWM3   A0A1I8QEF2   A0A1I8QED8   A0A168SJQ0   A0A0Q9XB93   A0A2J7QNV0   Q0GQR7   E0X9H9   C0L958   N0BMK4   C0L7I6   A0A1Q2T843   A0A1W4W3L2   A0A1W4W3K5   A0A1Q2T840   C0L956   E0X9I4   E0X9H8   E0X9I2   X5C002   K7ZRK2   A0A1B6DGU4   A0A2J7QNV2   A0A158NFE0   A0A1W4WFF3   A0A2J7QNV6   O17145   B0WN13   K7ILR9   A8DMT9   Q0IEP7   A0A1S4FJ60   D5FTG7   A0A0Q9XAW8   A0A2H1WJ59   Q16896   Q0GQR8   Q0ECT5   A0A0C9RM41   E0X9I3   A0A0K8STF5   A0A0K8TDA0   E0X9I1   A0A286Q6E9   D3UAF8   A0A2W1BQH7   A0A2A4JL08   A0A0A9WSU0   A0A2J7QNV9   A0A0K8TEH6   A0A226DL66   A0A195BDD7   A0A0K8STQ3  

Pubmed

20924418    10212398    23909412    29408355    22118469    24365472    + More
20513056    17880682    18362917    19820115    17994087    27288983    16902773    23841833    23156177    21347285    20075255    17510324    8391473    7704314    18093001    20087392    28756777    25401762   

EMBL

GQ890664    ADM88009.1    AJ224513    CAB41615.1    JN794059    AER59668.1    + More
AF006189    AAB62563.1    EF535530    ABQ45398.1    HM566200    KX856970    ADK74004.1    ASY91962.1    JN792582    AER59667.1    ODYU01002299    SOQ39604.1    AGBW02013810    OWR42773.1    LC171477    BAW87784.1    KX856966    ASY91958.1    AB278155    BAT57340.1    GQ890661    ADM88006.1    AB847423    BAN92442.1    KF881790    AHE41087.1    KX856969    ASY91961.1    AF006192    AAB62572.1    GQ890669    ADM88014.1    EF521821    ABP96889.1    KF881791    AHE41088.1    LC171472    BAW87779.1    LC171474    BAW87781.1    FJ665608    ACN52598.1    FJ665610    ACN52600.1    EF545117    KQ972204    ABU63595.1    KYB24596.1    EU273945    ABX47168.1    CH940647    EDW68497.2    KRF83882.1    FJ665607    ACN52597.1    EF545118    ABU63596.1    KYB24597.1    FJ668710    ACN53552.1    AB617631    BAL63029.1    EF156251    ABL86443.1    EF368369    ABN13426.1    KRF83883.1    KU201322    ANC68177.1    FJ668709    ACN53550.1    KJ174466    AHW29556.1    KJ485710    AJE68941.1    KC841916    AGK30293.1    KU201321    ANC68176.1    CH933809    EDW17470.2    KU201323    ANC68178.1    KRG05565.1    NEVH01012562    PNF30265.1    DQ667182    ABG75734.1    GQ890663    ADM88008.1    ACN53551.1    KC288141    AGK65036.2    FJ665609    ACN52599.1    LC171473    BAW87780.1    LC171471    BAW87778.1    ACN53549.1    GQ890668    ADM88013.1    GQ890662    ADM88007.1    GQ890666    ADM88011.1    KJ174465    AHW29555.1    AB697765    BAM66322.1    GEDC01012391    JAS24907.1    PNF30267.1    ADTU01014314    ADTU01014315    ADTU01014316    ADTU01014317    ADTU01014318    ADTU01014319    ADTU01014320    ADTU01014321    PNF30266.1    AF024647    AAB81966.1    DS232005    EDS31424.1    EF545116    ABU63594.1    EFA12941.2    CH477504    EAT39884.1    FJ851098    ACZ51430.1    KRG05564.1    ODYU01009008    SOQ53088.1    U28803    AAA68961.1    DQ667181    ABG75733.1    AB253526    BAF31884.1    GBYB01008046    JAG77813.1    GQ890667    ADM88012.1    GBRD01009258    JAG56563.1    GBRD01002284    JAG63537.1    GQ890665    ADM88010.1    KX592155    APM83156.1    FJ851097    ACZ51429.1    KZ149977    PZC75884.1    NWSH01001075    PCG72737.1    GBHO01032740    JAG10864.1    PNF30268.1    GBRD01002286    JAG63535.1    LNIX01000017    OXA45738.1    KQ976514    KYM82205.1    GBRD01009260    JAG56561.1   

Proteomes

UP000007151    UP000192223    UP000007266    UP000008792    UP000095300    UP000009192    + More
UP000235965    UP000005205    UP000002320    UP000002358    UP000008820    UP000218220    UP000198287    UP000078540   

PRIDE

E0X9I0    E0X9H7    U3TMA1    E0X9I5    A5A2M7    E0X9H9    + More
E0X9I4    E0X9H8    E0X9I2    E0X9I3    E0X9I1   

Pfam

PF02932   Neur_chan_memb        + More
PF02931   Neur_chan_LBD

Interpro

IPR036719   Neuro-gated_channel_TM_sf        + More
IPR006202   Neur_chan_lig-bd       
IPR006028   GABAA/Glycine_rcpt       
IPR006029   Neurotrans-gated_channel_TM       
IPR036734   Neur_chan_lig-bd_sf       
IPR002289   GABAAb_rcpt       
IPR006201   Neur_channel       
IPR018000   Neurotransmitter_ion_chnl_CS       

SUPFAM

SSF90112   SSF90112        + More
SSF63712   SSF63712       

Gene 3D

2.70.170.10    

ProteinModelPortal

E0X9I0   Q9XZW0   G8IIS8   O18468   A5JJ42   E2IKR3   + More
G8IIR9   A0A2H1VH64   A0A212EMQ5   A0A1Q2T844   A0A3G1J4Z2   A0A0U5ACA3   E0X9H7   U3TMA1   V9ZCF2   A0A2S0DGE1   O18471   E0X9I5   A5A2M7   V9Z984   A0A1W4WE55   A0A1W4W3J7   A0A1Q2T839   A0A1Q2T841   C0L7I5   C0L7I7   A0A1W4WF43   A0A1W4WE60   A8DMU0   A9LYI3   B4LHG7   A0A0Q9WHF3   C0L7I4   A8DMU1   C0L957   A0A1I8QEE6   H3JU08   A0A1I8QEJ2   A1Z0K6   A3FBG6   A0A0Q9WTB8   A0A168SJP2   C0L955   X5BIT8   A0A0B5EEN9   M9Z6B1   A0A168SJJ0   B4KWM3   A0A1I8QEF2   A0A1I8QED8   A0A168SJQ0   A0A0Q9XB93   A0A2J7QNV0   Q0GQR7   E0X9H9   C0L958   N0BMK4   C0L7I6   A0A1Q2T843   A0A1W4W3L2   A0A1W4W3K5   A0A1Q2T840   C0L956   E0X9I4   E0X9H8   E0X9I2   X5C002   K7ZRK2   A0A1B6DGU4   A0A2J7QNV2   A0A158NFE0   A0A1W4WFF3   A0A2J7QNV6   O17145   B0WN13   K7ILR9   A8DMT9   Q0IEP7   A0A1S4FJ60   D5FTG7   A0A0Q9XAW8   A0A2H1WJ59   Q16896   Q0GQR8   Q0ECT5   A0A0C9RM41   E0X9I3   A0A0K8STF5   A0A0K8TDA0   E0X9I1   A0A286Q6E9   D3UAF8   A0A2W1BQH7   A0A2A4JL08   A0A0A9WSU0   A0A2J7QNV9   A0A0K8TEH6   A0A226DL66   A0A195BDD7   A0A0K8STQ3  

PDB

6DW1     E-value=1.67037e-75,     Score=720

KEGG

100500924    K05181 gamma-aminobutyric acid receptor subunit beta | (RefSeq) RDL2; ionotropic GABA-aminobutyric a

PATHWAY

04080    Neuroactive ligand-receptor interaction - Bombyx mori (domestic silkworm)

GO

GO:0004890   GO:0005886   GO:0005230   GO:0016021   GO:0006811   GO:0043005   GO:0045202   GO:0005887   GO:0050877   GO:0007268   GO:0034220   GO:0007165   GO:0042391   GO:0016020   GO:0006810   GO:0005216   GO:0006508   GO:0007169   GO:0004888  

PANTHER

PTHR18945  

Length:

459

Number of predicted TMHs:

4

Exp number of AAs in TMHs:

87.19527

Exp number, first 60 AAs:

0.06256

Total prob of N-in:

0.01083

outside

1  -  216

TMhelix

217  -  239

inside

240  -  247

TMhelix

248  -  270

outside

271  -  279

TMhelix

280  -  302

inside

303  -  423

TMhelix

424  -  441

outside

442  -  459

 

 

Pi

16.591395

Theta

16.952054

Tajima's D

-0.300312

CLR

0.004263

CSRT

0.283385830708465

Interpretation

Uncertain