Gene

KWMTBOMO00224

Pre Gene Modal

BGIBMGA000640

Annotation

cytochrome_P450_Cyp305B1_precursor_[Bombyx_mori]

Location

Bomo_Chr1(+):7396698-7418789      View in EpiBrowser

Full name

Probable cytochrome P450 305a1      

Alternative Name

CYPCCCVA1

Location in the cell

PlasmaMembrane   Reliability : 3.178

CDS

ATGCTGCCAGTGCTTGTTTGCATAATAGTTATCGTATTAATCTGTTGTAATGTCATCAGAAGTGTAATCAAACCCGAGAAATTTCCTCCAGGTCCGATATGGTATCCATTTTTTGGCAGCAGCTCAATTGTTCAACAAATGACAAGCAAACACGGGTCGCAGTGGAAAGCGTTACTGGAACTTTCGAAACAGTGGTCCACTCAGGTTCTCGGCTTAAAACTAGGAAGAGAATTAGTGGTCGTCGTCTACGGGGAGAAGAATGTTCGTCAAGTGTTCTCGGAATCCGAGTTCGACGGTCGACCGAACTCTTTCTTCTATAAGTTGAGATGTCTCGGAAAACGACTCGGCGTCACCTTTGTTGATGGTCCTCTTTGGCGAGAACACAGACAGTTCACTGTAAAACATTTAAAGAATGTTGGTTTTGGTAAGACATCGATGGAGCTGGAAATCCAAAACGAATTGAAGTTGTTACGTGAATACATAAATGATAATAAACATAAGCCAATAAAAGTTGATAGTATGTTTTCATCGGCCGTAATGAATGTTTTATGGAAGTATGTAGCAGGCGAGAGAATCAGAGAAGACAAATTAGAACGTTTACTTGAACTATTCTATTTGAGATCGAAGGCGTTCACTTTGACTGGTGGCTTGCTAAGCCAAATACCTTGGTGCAGGTTCATTATACCCGGCCTAAGTGGGTACAAACTAATAGTTGACTTGAACCAGCAGATATCTGAAATTATTGAGGAAGCCATAAAAAAGCATTTAAACAAAGAAGTGCAACAGAACGATTTTATATATTCGTTCTTAGATGAAATGAACGAAGAGAACAAGGCATCATTTACGTACGATCAGCTGAAAACCGTGTGCCTTGATCTAATAATAGCCGGATCCCAAACAACAGGGAACGCTGTTAAGTTTGCTCTTCTATCAGTTTTGCGAAACAAAAACATTCAAGAAAAAATCTTCAACGAAATAGAAAACACCATTGGCGATTCTATGCCTTGCTGGGCTGACAGTAGCAAACTCGTATATACATCGGCATTTCTGCTGGAAGTAATGAGAATTCACACAATAGCGCCCCTGGCTGGTCCTCGAAGAGTTTTACAGGACACAGTCATCGACGGCTACGTTATACCTAAAGAGACGACGGTTCTGATATCCTTGGCCGATATTCACTTGGATCCGAATCTGTGGCCGGATCCTCACGAAATAAAGCCGGAGAGGTTTATCGACGAAAAAGGATTATCGAAAAGTAATGAACACATCTATCCTTTTGGATCAGGTCGGAGACGTTGCCCAGGCGATTCGCTGGCCAGGTCTTTCGTCTTTATCATATTTGTTGGGATCCTGCAGAAGTACAGAATAGACTGTGTCAATGGAGTATTGCCGTCTAACGAAGCTGACATAGGCTTGCTTGCGGCTCCAAAACCTTTTGTCGCTAATTTCGTATCAAGAGAGTAA

Protein

MLPVLVCIIVIVLICCNVIRSVIKPEKFPPGPIWYPFFGSSSIVQQMTSKHGSQWKALLELSKQWSTQVLGLKLGRELVVVVYGEKNVRQVFSESEFDGRPNSFFYKLRCLGKRLGVTFVDGPLWREHRQFTVKHLKNVGFGKTSMELEIQNELKLLREYINDNKHKPIKVDSMFSSAVMNVLWKYVAGERIREDKLERLLELFYLRSKAFTLTGGLLSQIPWCRFIIPGLSGYKLIVDLNQQISEIIEEAIKKHLNKEVQQNDFIYSFLDEMNEENKASFTYDQLKTVCLDLIIAGSQTTGNAVKFALLSVLRNKNIQEKIFNEIENTIGDSMPCWADSSKLVYTSAFLLEVMRIHTIAPLAGPRRVLQDTVIDGYVIPKETTVLISLADIHLDPNLWPDPHEIKPERFIDEKGLSKSNEHIYPFGSGRRRCPGDSLARSFVFIIFVGILQKYRIDCVNGVLPSNEADIGLLAAPKPFVANFVSRE

Description

May be involved in the metabolism of insect hormones and in the breakdown of synthetic insecticides.

Cofactor

heme

Similarity

Belongs to the cytochrome P450 family.

Keywords

Complete proteome   Endoplasmic reticulum   Heme   Iron   Membrane   Metal-binding   Microsome   Monooxygenase   Oxidoreductase   Reference proteome  

Feature

chain  Probable cytochrome P450 305a1

Uniprot

L0N6J8   Q2L9Y9   Q9NDL3   H9ITR0   A0A0C5C541   A0A248QEI5   + More
A0A1V0D9F4   T1WK13   A0A2W1BLF5   A0A068EU19   A0A194QB17   A0A194QZY0   A0A212EMV4   X5D4F5   A0A286MXN2   A0A212EMN8   Q17JA9   A0A1W5KJU1   Q17JB0   A0A336N4L8   A0A336K893   A0A1J1IIJ5   A0A1B6F8W0   A0A1B0FC64   A0A1Q3G500   A0A182PZ34   A0A1B6HAC5   A0A0K1YWH2   A0A068F800   A0A1Y1JZV7   A0A0A1WHE4   A0A0M3QWH8   A0A182LX08   A0A1J1I412   A0A182QNR3   A0A182RFA6   A0A3F2Z158   B4L0X7   A0A2J7QMN4   A0A1W4WN12   A0A1A9WS92   A0A0L0C6F8   D6WFY5   A0A084W481   B3NIJ0   A0A3F2YW28   A0A248ADT7   A0A1B0C6V2   B4LBM9   A0A0K8VYF8   A0A290GNU1   A0A084W482   A0A182KC89   A0A1A9Z3L0   A0A182Y1B2   A0A182PHN4   W5JLT1   A0A034VQK2   A0A1Q1NL12   A0A1A9XBI4   A0A0K0LB87   A0A1A9UXW5   A0A125S6P6   A0A182UIL2   A0A182XUJ9   Q7Q6U9   A0A182HWR4   Q5TRI3   A0A182FZX1   K4JN85   A0A1I8MUR4   B4QQY9   Q7QLM0   W5JL39   A0A182FZX0   B4IXQ0   B3M8U6   Q9VW43   A0A182XUK0   A0A182UV89   B4IIQ9   A0A0K0LC82   A0A182VJM2   A0A1B6BXF9   A0A0K8SBH9   A0A067QG21   A0A0A9XER8   J9K9I4   A0A1I8NQB8   A0A182NGX6   A0A182Y1B3   B4H921   B4IUD3   Q2M000   A0A1B0DPF7   B4PFX8   Q7PIP7   A0A1W4VUW0   B0X5V2   N6U564  

EC Number

1.14.-.-

Pubmed

19121390    28881445    22984814    28756777    26354079    22118469    + More
24361403    19954531    25299618    17510324    25880816    28004739    25830018    17994087    26108605    18362917    19820115    24438588    25244985    20920257    23761445    25348373    28092127    12364791    14747013    17210077    24324548    25315136    22936249    9087549    10731132    12537572    12537569    24845553    25401762    17550304    15632085    23537049   

EMBL

AK289325    BAM73852.1    DQ342362    ABC69163.1    DQ417659    AB044900    + More
ABD78849.1    BAA96811.1    BABH01006864    BABH01006865    KP001120    AJN91165.1    KX443454    ASO98029.1    KY212065    ARA91629.1    JQ979047    AGU36301.1    KZ149977    PZC75879.1    KM016702    AID54854.1    KQ459463    KPJ00616.1    KQ461108    KPJ09151.1    AGBW02013811    OWR42771.1    KF701126    AHW57296.1    MF684350    ASX93984.1    OWR42770.1    CH477233    EAT46796.1    KU941587    AMR44690.1    EAT46795.1    UFQS01002401    UFQT01002401    SSX13959.1    SSX33378.1    UFQS01000067    UFQT01000067    SSW98983.1    SSX19365.1    CVRI01000054    CRL00053.1    GECZ01023087    JAS46682.1    CCAG010016073    GFDL01000171    JAV34874.1    GECU01036119    JAS71587.1    KP859378    AKZ17688.1    KJ702243    AID61397.1    GEZM01098710    JAV53791.1    GBXI01016362    JAC97929.1    CP012525    ALC44173.1    AXCM01013784    CVRI01000040    CRK95079.1    AXCN02000360    CH933809    EDW19227.1    NEVH01013204    PNF29828.1    JRES01000836    KNC27860.1    KQ971328    EFA01265.1    ATLV01020285    KE525297    KFB45025.1    CH954178    EDV52415.1    KX708494    ARG41841.1    JXJN01027023    JXJN01027024    CH940647    EDW70839.1    GDHF01034073    GDHF01008366    JAI18241.1    JAI43948.1    KX945358    ATB55046.1    KFB45026.1    ADMH02000773    ETN65091.1    GAKP01014238    JAC44714.1    KX660731    AQM57070.1    KM217012    AIW79975.1    KT601138    AME15807.1    AAAB01008960    EAA11827.3    APCN01001532    EAL39881.2    JX876511    AFU86441.1    CM000363    CM002912    EDX11127.1    KMZ00615.1    AAAB01006489    EAA02774.4    ETN65092.1    CH916366    EDV97512.1    CH902618    EDV41097.1    AE014296    AY051626    CH480844    EDW49830.1    KM217011    AIW79974.1    GEDC01031608    JAS05690.1    GBRD01015197    GBRD01015196    GBRD01015194    GBRD01015193    JAG50633.1    KK853574    KDR06612.1    GBHO01026291    GBHO01026290    GBHO01026288    GBHO01026286    JAG17313.1    JAG17314.1    JAG17316.1    JAG17318.1    ABLF02021786    CH479226    EDW35236.1    CH891868    EDW99996.1    CH379069    EAL31137.1    AJVK01008091    CM000159    EDW95275.1    EAA44065.3    DS232396    EDS41083.1    APGK01039300    APGK01039301    KB740969    ENN76740.1   

Proteomes

UP000005204    UP000053268    UP000053240    UP000007151    UP000008820    UP000183832    + More
UP000092444    UP000075885    UP000092553    UP000075883    UP000075886    UP000075900    UP000075920    UP000009192    UP000235965    UP000192223    UP000091820    UP000037069    UP000007266    UP000030765    UP000008711    UP000075884    UP000092460    UP000008792    UP000075881    UP000092445    UP000076408    UP000000673    UP000092443    UP000078200    UP000075902    UP000076407    UP000007062    UP000075840    UP000069272    UP000095301    UP000000304    UP000001070    UP000007801    UP000000803    UP000075903    UP000001292    UP000027135    UP000007819    UP000095300    UP000008744    UP000002282    UP000001819    UP000092462    UP000192221    UP000002320    UP000019118   

PRIDE

L0N6J8    Q9NDL3    H9ITR0    Q9VW43   

Pfam

PF00067   p450

Interpro

IPR036396   Cyt_P450_sf        + More
IPR002401   Cyt_P450_E_grp-I       
IPR001128   Cyt_P450       
IPR017972   Cyt_P450_CS       

SUPFAM

SSF48264   SSF48264       

Gene 3D

1.10.630.10    

ProteinModelPortal

L0N6J8   Q2L9Y9   Q9NDL3   H9ITR0   A0A0C5C541   A0A248QEI5   + More
A0A1V0D9F4   T1WK13   A0A2W1BLF5   A0A068EU19   A0A194QB17   A0A194QZY0   A0A212EMV4   X5D4F5   A0A286MXN2   A0A212EMN8   Q17JA9   A0A1W5KJU1   Q17JB0   A0A336N4L8   A0A336K893   A0A1J1IIJ5   A0A1B6F8W0   A0A1B0FC64   A0A1Q3G500   A0A182PZ34   A0A1B6HAC5   A0A0K1YWH2   A0A068F800   A0A1Y1JZV7   A0A0A1WHE4   A0A0M3QWH8   A0A182LX08   A0A1J1I412   A0A182QNR3   A0A182RFA6   A0A3F2Z158   B4L0X7   A0A2J7QMN4   A0A1W4WN12   A0A1A9WS92   A0A0L0C6F8   D6WFY5   A0A084W481   B3NIJ0   A0A3F2YW28   A0A248ADT7   A0A1B0C6V2   B4LBM9   A0A0K8VYF8   A0A290GNU1   A0A084W482   A0A182KC89   A0A1A9Z3L0   A0A182Y1B2   A0A182PHN4   W5JLT1   A0A034VQK2   A0A1Q1NL12   A0A1A9XBI4   A0A0K0LB87   A0A1A9UXW5   A0A125S6P6   A0A182UIL2   A0A182XUJ9   Q7Q6U9   A0A182HWR4   Q5TRI3   A0A182FZX1   K4JN85   A0A1I8MUR4   B4QQY9   Q7QLM0   W5JL39   A0A182FZX0   B4IXQ0   B3M8U6   Q9VW43   A0A182XUK0   A0A182UV89   B4IIQ9   A0A0K0LC82   A0A182VJM2   A0A1B6BXF9   A0A0K8SBH9   A0A067QG21   A0A0A9XER8   J9K9I4   A0A1I8NQB8   A0A182NGX6   A0A182Y1B3   B4H921   B4IUD3   Q2M000   A0A1B0DPF7   B4PFX8   Q7PIP7   A0A1W4VUW0   B0X5V2   N6U564  

PDB

3DL9     E-value=3.43014e-48,     Score=484

KEGG

100127103    no KO assigned | (RefSeq) Cyp305b1, CYP305A1; cytochrome P450 Cyp305B1

GO

GO:0004497   GO:0005506   GO:0016705   GO:0020037   GO:0016021   GO:0042738   GO:0016712   GO:0043231   GO:0008395   GO:0055114   GO:0006082   GO:0005737   GO:0006805   GO:0005789   GO:0005634   GO:0005622   GO:0030145   GO:0006508   GO:0007169  

Subcellular location

Endoplasmic reticulum membrane  
Microsome membrane  

SignalP

Position:   1 - 21,         Likelihood:  0.903595

 

 

Length:

487

Number of predicted TMHs:

1

Exp number of AAs in TMHs:

17.4823199999999

Exp number, first 60 AAs:

17.29076

Total prob of N-in:

0.82041

POSSIBLE N-term signal

sequence

inside

1  -  1

TMhelix

2  -  23

outside

24  -  487

 

 

Pi

22.677114

Theta

24.930991

Tajima's D

-0.767903

CLR

0.053699

CSRT

0.187890605469727

Interpretation

Uncertain