Gene

KWMTBOMO00199

Pre Gene Modal

BGIBMGA000587

Annotation

PREDICTED:_discoidin_domain-containing_receptor_2-like_isoform_X1_[Amyelois_transitella]

Location

Bomo_Chr1(-):6227134-6272752      View in EpiBrowser

Location in the cell

Cytoplasmic   Reliability : 1.402 Nuclear   Reliability : 1.102

CDS

ATGGAGAGCGGCCTGATTGCCGACAAGGACGTCACTGCTAGTTCTTGTTATAACGATGGCAACGTCGCGCCGCAGAACGGAAGGCTAAATCAAGACATCAAAGGAGGTGCATGGTGTCCTAGATCCCAAATCACGACTGAATCCACAGAGTGGCTAGAAATTGACCTTCACACTGTACACGTAATCACCGGTGCAGGCACCCAGGGTCGTTTCGGTAACGGCCAAGGTCAAGAGTACGCGGAGGCCTACGTACTTGAATATTGGCGCCCTAAACTTGGGAAATGGGTACGATACAGGAGCTTAGACGGCCAAGAGAAACTGACCGGTAATACTAACACATACTTGGAAAAGAAGAATCATCTAGAGCCGCCGATCTGGGCGTCCAAAGTTCGTTTCATTCCTTACAGTTCGCATAGACGGACTGTTTGTATGAGAGTTGAATTGTATGGATGCTATTGGAGCGTGGGAGTGGTTTCGTATTCGATGCCTAAAGGCGATAGACGTAGTAATGGAATCGAACTCACGGACATGATCTACGACGGTCAGTGGGGCGAGGAGCTCCGCGGGGGCTTGGGCCAACTGGTGGACGGTCAGTTCGGAAGCGACGACATCCGAGAAGCCTCTAAGAACTCCGCCTGGGTCGGCTGGAGAAACGACTCGAGACCAGATCCCCCGGTCATCATATTCGAATTCGACAAAGTCCGCGAGTTCAGCGCTGTACATATATTTTGTAATAATAAGTTCATGAGGGATGTACTAGTGTTCTCTGAAGCAATTATATCATTTTCGATCGGCGGTCGTCACTTTCAAGACGAACCTATCCACTATACATACGTTCAAGACAAGATCTTCGAGAACGCTCGTAACGTGAGCATTAAACTACACCATAGAATAGGGAAGTGGGTGCGGATCGAACTTCAGTTTGCCGCGAGGTGGATACTTGTTAGCGAGATCGTTTTTGATTCAGACGTAGCACAAGGCAATTACACACCGGAAAGTATGAAGCCACCGGTCAGTAAGGATAAAACGAAAGTGATTTCAAGTAAAGAGGTACCTATTTCGACGGCCCATCAGGAAGATCCGCTGTACGTCGCGATTGTCGTGGGAGTGTTGACCGCTCTCGTCATACTGTTGGCCGTTGCGATATTCCTTATAATACACCGACACAAACATAGGAAGTGTTTCGCTTCTCCGCTTGCGAAGTCGGCTGTCTCGCAGAAACGGGCCGTTGAGAGCTACAGTGGGTGCGGTACGTCTATGCTACCCGAGAACAAAATGATCTTAGACTGCGGTCTCGATGTCAAGTCAGACGAGTACCAGGAGCCCTATCAGGCTCTCAAATGCGCTCCCTACTTTAGTTACAGCACGGTCCTGCTCGAGATGAAAGATTTTAAGGACTCCAACACCGCGCTCTCTGACAGTTCGAACTACGATTATGCGGTACCAGAATTGAGTTCGGCTCCGTTGTTAACGAAGCGGATGGGAGAAACGCTTTCCCAGCAAGCTACCGAGCTTGTTGGCGAGCCGATGGACACGTTACCTGACCTCGGAACGAGACGATCCCTCAATCCTTCCGTACGATCCAAACAAAGCACGAGATCGCCGAGTCAACAAGAAATATTGTTGGATCTGAAGAGACGCCTCGAAACTACTAACGTTATTGAGTTCCCGAGGCACAGACTCCGGATGATCTCTAAGTTAGCCGAGGGCGCCTTCGGAACCGTTTACGTAGCGGAAGCGGACGGTGTGCCTGAATATAACGGAGCCATTACGTCGGAGAAGAGATTAGTGGCCGTCAAATTCTTATGTCACGACGCCACGCTCAAGGAGAGGTATATCATGGAGGAGTTCGAACGCGACGTCCGCATATTGGCCGCGTTGTCCTCGCCTCACCTCGCGAGGGTATTGGGCGCGTGTCGCTCGCCGCCCCTCGCCGTGGTGCTGGAGTACCTTGAGCTCGGGGACCTGTGTGCGTTCCTGCGGGCTGCTATTCCGCCGACGGCAGCCACGCTCCTGCACATTGCCACGCAGATAGCCGCTGGAATGCAATACCTCGAATCGCTCAATTTCGTTCACAGGGACTTAGCAGCTAGGAATTGTCTGATCGGGAAGGGTTATCAAATTAAAATAAGCGATTTCGGCACCGACAACGAGGCGTACACTTGCGACTATTATAAAGTGGACGGTCGCGTACCGCTGCCTCTGCGCTGGGCGGCCTGGGAGTCGGTGCTCCGGGGAAAGTACACGACCAAGAGCGACGTGTGGGCGTTCGCGGTCACGCTGCACGAGATATACTCGCTCTGCCGACGGCGCCCCTACGAGCACCTAACCGACTGCGAGGTTTTGGATAATCTGTCGCACTTACAAGCGGACGACGGTATGTTCGAGTGCGTCGACCGCGCCCCCGGCTGTCCCCGGGACCTCTACGAGCTGATGCTGGAATGCTGGCGGAGAGACGAACTGGACCGGCCCACGTTCGGTGAGATCCATCTCTTCCTGCAGCGCAAGAGTCTCAACTACGCGACCACGTGA

Protein

MESGLIADKDVTASSCYNDGNVAPQNGRLNQDIKGGAWCPRSQITTESTEWLEIDLHTVHVITGAGTQGRFGNGQGQEYAEAYVLEYWRPKLGKWVRYRSLDGQEKLTGNTNTYLEKKNHLEPPIWASKVRFIPYSSHRRTVCMRVELYGCYWSVGVVSYSMPKGDRRSNGIELTDMIYDGQWGEELRGGLGQLVDGQFGSDDIREASKNSAWVGWRNDSRPDPPVIIFEFDKVREFSAVHIFCNNKFMRDVLVFSEAIISFSIGGRHFQDEPIHYTYVQDKIFENARNVSIKLHHRIGKWVRIELQFAARWILVSEIVFDSDVAQGNYTPESMKPPVSKDKTKVISSKEVPISTAHQEDPLYVAIVVGVLTALVILLAVAIFLIIHRHKHRKCFASPLAKSAVSQKRAVESYSGCGTSMLPENKMILDCGLDVKSDEYQEPYQALKCAPYFSYSTVLLEMKDFKDSNTALSDSSNYDYAVPELSSAPLLTKRMGETLSQQATELVGEPMDTLPDLGTRRSLNPSVRSKQSTRSPSQQEILLDLKRRLETTNVIEFPRHRLRMISKLAEGAFGTVYVAEADGVPEYNGAITSEKRLVAVKFLCHDATLKERYIMEEFERDVRILAALSSPHLARVLGACRSPPLAVVLEYLELGDLCAFLRAAIPPTAATLLHIATQIAAGMQYLESLNFVHRDLAARNCLIGKGYQIKISDFGTDNEAYTCDYYKVDGRVPLPLRWAAWESVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYEHLTDCEVLDNLSHLQADDGMFECVDRAPGCPRDLYELMLECWRRDELDRPTFGEIHLFLQRKSLNYATT

Similarity

Belongs to the protein kinase superfamily. Tyr protein kinase family.

Uniprot

H9ITK7   A0A2H1VWV3   A0A2W1BNK7   A0A194QW37   A0A212FMA3   A0A2A4JAE7   + More
A0A2A4JBL3   A0A194PSB9   A0A195FPJ0   A0A3L8DQC9   A0A146LSE5   A0A067R7Z8   A0A0C9RLC0   A0A1W4WM45   A0A1B6LKK5   D6WFT6   A0A232FAP8   A0A1Y1LZ85   A0A158NFP8   J9JU75   A0A2H8TKL8   A0A2S2P6A0   A0A2S2QVE2   A0A2A3EKL6   E0W014   A0A151WPD5   A0A0U3U674   A0A087ZZC4   T1I6J0   T1J7A6   A0A1B6DPL3   A0A226EK82   A0A310S6X0   A0A1B6I1Y9  

Pubmed

19121390    28756777    26354079    22118469    30249741    26823975    + More
24845553    18362917    19820115    28648823    28004739    21347285    20566863   

EMBL

BABH01006764    BABH01006765    BABH01006766    ODYU01004929    SOQ45310.1    KZ150006    + More
PZC75214.1    KQ461108    KPJ09180.1    AGBW02007654    OWR54875.1    NWSH01002247    PCG68819.1    PCG68820.1    KQ459594    KPI96207.1    KQ981340    KYN42505.1    QOIP01000005    RLU22645.1    GDHC01009279    JAQ09350.1    KK852638    KDR19671.1    GBYB01009070    JAG78837.1    GEBQ01015779    JAT24198.1    KQ971319    EEZ99592.2    NNAY01000610    OXU27407.1    GEZM01046289    JAV77355.1    ADTU01014467    ADTU01014468    ADTU01014469    ADTU01014470    ADTU01014471    ADTU01014472    ADTU01014473    ADTU01014474    ADTU01014475    ADTU01014476    ABLF02040549    GFXV01002880    MBW14685.1    GGMR01012402    MBY25021.1    GGMS01012515    MBY81718.1    KZ288230    PBC31571.1    DS235854    EEB18970.1    KQ982877    KYQ49690.1    KT355578    ALV82497.1    ACPB03008763    JH431916    GEDC01009674    JAS27624.1    LNIX01000003    OXA57161.1    KQ767065    OAD53524.1    GECU01026831    JAS80875.1   

Proteomes

UP000005204    UP000053240    UP000007151    UP000218220    UP000053268    UP000078541    + More
UP000279307    UP000027135    UP000192223    UP000007266    UP000215335    UP000005205    UP000007819    UP000242457    UP000009046    UP000075809    UP000005203    UP000015103    UP000198287   

PRIDE

H9ITK7   

Pfam

PF07714   Pkinase_Tyr        + More
PF00754   F5_F8_type_C

Interpro

IPR000719   Prot_kinase_dom        + More
IPR008266   Tyr_kinase_AS       
IPR020635   Tyr_kinase_cat_dom       
IPR008979   Galactose-bd-like_sf       
IPR000421   FA58C       
IPR001245   Ser-Thr/Tyr_kinase_cat_dom       
IPR011009   Kinase-like_dom_sf       
IPR017441   Protein_kinase_ATP_BS       

SUPFAM

SSF56112   SSF56112        + More
SSF49785   SSF49785       

Gene 3D

2.60.120.260    

CDD

cd00057  FA58C

ProteinModelPortal

H9ITK7   A0A2H1VWV3   A0A2W1BNK7   A0A194QW37   A0A212FMA3   A0A2A4JAE7   + More
A0A2A4JBL3   A0A194PSB9   A0A195FPJ0   A0A3L8DQC9   A0A146LSE5   A0A067R7Z8   A0A0C9RLC0   A0A1W4WM45   A0A1B6LKK5   D6WFT6   A0A232FAP8   A0A1Y1LZ85   A0A158NFP8   J9JU75   A0A2H8TKL8   A0A2S2P6A0   A0A2S2QVE2   A0A2A3EKL6   E0W014   A0A151WPD5   A0A0U3U674   A0A087ZZC4   T1I6J0   T1J7A6   A0A1B6DPL3   A0A226EK82   A0A310S6X0   A0A1B6I1Y9  

PDB

5BVW     E-value=8.23698e-71,     Score=682

KEGG

100141458    K05125 discoidin domain receptor family member 2 [EC:2.7.10.1] | (RefSeq) Tkz, Bmtkz; tyrosine kinas

GO

GO:0005524   GO:0016021   GO:0004713   GO:0005887   GO:0038062   GO:0001952   GO:0030154   GO:0043235   GO:0007160   GO:0007169   GO:0004714   GO:0008284   GO:1903053   GO:0005518   GO:0004672   GO:0006468   GO:0005622   GO:0030145   GO:0006508  

Length:

843

Number of predicted TMHs:

1

Exp number of AAs in TMHs:

25.40534

Exp number, first 60 AAs:

0.00011

Total prob of N-in:

0.28767

outside

1  -  363

TMhelix

364  -  386

inside

387  -  843

 

 

Pi

17.863335

Theta

17.629928

Tajima's D

0.060399

CLR

0.0916

CSRT

0.396030198490075

Interpretation

Uncertain