Gene

KWMTBOMO00184  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA000619

Annotation

FK506-binding_protein_precursor_[Bombyx_mori]

Location

Bomo_Chr1(+):5918913-5958396      View in EpiBrowser

Full name

Peptidylprolyl isomerase      

Location in the cell

Cytoplasmic   Reliability : 2.22

CDS

ATGACGACGTTGCGCTGCGTGCTTATGCTGGTTGCCTTGGCCGGGGCCACGTTCGCGGGTCCTGAGGTCACTGAACTAAAGACAGAAGTAGTTAGCGTTCCAGAAGGATGCACCACGAAGTCCAAGCACGGCGATATGCTCACCATGCACTACACTGGCACGCTAGACGACGGACACAAGTTCGACTCGAGTTATGATCGCGATCAACCTTTTACGTTCCAAATTGGCGTTGGGCAAGTGATCAAGGGATGGGACCAGGGCTTGCTTGACATGTGCGTTGGTGAGAAACGTAAACTGACTATTCCCGCATCCTTGGGCTACGGAGAGCGCGGAGCCGGCAACGTGATTCCTCCCCACGCTACATTGCATTTCGAAGTGGAGTTGATCAACATCGGTGACTCTCCACCGGCCACAAACGTGTTCAAGGAAATCGACGCCGATAAGGACAACATGCTCTCCCGCGAAGAAGTGAGCGACTATTTGAAGAAGCAGATGGTTCCCGCCGACGGTGGTGAAGTAAGCGAAGACATCAAGCAAATGTTGGAAAGTCACGATAAACTTGTTGAGGAAATCTTCCAGCACGAAGATAAAGACAAAAACGGCTTCATCAGCCATGAGGAATTCTCTGGACCTAAGCACGACGAACTTTAA

Protein

MTTLRCVLMLVALAGATFAGPEVTELKTEVVSVPEGCTTKSKHGDMLTMHYTGTLDDGHKFDSSYDRDQPFTFQIGVGQVIKGWDQGLLDMCVGEKRKLTIPASLGYGERGAGNVIPPHATLHFEVELINIGDSPPATNVFKEIDADKDNMLSREEVSDYLKKQMVPADGGEVSEDIKQMLESHDKLVEEIFQHEDKDKNGFISHEEFSGPKHDEL

Catalytic Activity

[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)

Feature

chain  Peptidylprolyl isomerase

Uniprot

S4PG11   L0GGU3   A0A220K8J7   I4DIM0   I4DLY3   J3JZ98   + More
A0A182Y995   A0A1W4WGT9   T1DNF6   A0A2M3Z9P5   A0A2M4BZI1   A0A1Q3FV17   A0A2M4DQJ0   A0A2M4AGG7   Q17D71   A0A023EIK3   Q7Q835   L0AT90   A0A182NZ07   A0A023EJR0   D6WID8   A0A2C9GQ82   A0A1B6LS89   A0A1L8DU55   Q8T109   A0A195BV65   A0A1B6J2N5   A0A0K8UQZ9   A0A067RDM7   T1E2D9   A0A1J1ILH6   R4G3D6   K7J7N8   A0A1I9WL39   A0A151JAE4   A0A1B6EJZ3   A0A195FJN6   A0A212EMM7   A0A0C9QAU9   A0A034VUV5   A0A151WTQ4   W8CBT8   D3TSE2   A0A1I8PQR6   A0A0A1XDE5   A0A1L8EE53   A0A0K8VEV8   A0A3L8DYY5   A0A348G6B3   Q9V3V2   W8BLS7   A0A034VVT0   T1PBE6   A0A0L0CFE3   Q6NL72   A0A0Q9XAU1   B3MC59   B4KRE5   A0A0J9RJD1   A0A195D3B1   A0A3B0J637   B4LLG4   B3NMW4   B4I7Q6   B4QG37   B4P8Z0   Q9XZ54   A0A0A1XLL2   A0A1L8EIJ9   A0A1W4VY64   B4MJV3   A0A1J0M5H2   V9IJH7   A0A0B4K7C5   A0A0M4EIP6   Q28XN1   B4GHA7   A0A0Q9XFJ7   A0A0N8P038   A0A0Q9XL14   A0A0Q9WIS7   A0A0J9U7Q3   A0A0R1DRF0   B4J7K2   A0A1W4W934   A0A2A3E4Z8   A0A1W6EVW0   A0A336MMX6   A0A146LPM4   A0A0A9X018   A0A0R3NPR0   A0A1B6CH61   J9JT30   A0A2S2QC67   A0A2H8TN45   E0VW77   A0A2S2PH04   A0A194PT98   A0A3B0J6E6   A0A1Y1LUW0  

EC Number

5.2.1.8

Pubmed

23622113    28630352    22651552    22516182    25244985    17510324    + More
24945155    12364791    14747013    17210077    18362917    19820115    12715162    24845553    24330624    20075255    27538518    22118469    25348373    24495485    20353571    25830018    30249741    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    26109357    26109356    25315136    26108605    17994087    22936249    17550304    15632085    18057021    26823975    25401762    23185243    20566863    26354079    28004739   

EMBL

GAIX01002716    JAA89844.1    JX946657    AGA84515.1    MF319696    ASJ26410.1    + More
AK401138    BAM17760.1    AK402301    BAM18923.1    BT128579    AEE63536.1    GAMD01002930    JAA98660.1    GGFM01004444    MBW25195.1    GGFJ01009349    MBW58490.1    GFDL01003628    JAV31417.1    GGFL01015230    MBW79408.1    GGFK01006552    MBW39873.1    CH477299    EAT44298.1    GAPW01004342    GAPW01004341    GAPW01004340    GAPW01004339    GEHC01000375    JAC09258.1    JAV47270.1    AAAB01008944    EAA10152.4    JX879123    AFZ78832.1    GAPW01004338    JAC09260.1    KQ971334    EEZ99684.1    APCN01000634    GEBQ01013452    JAT26525.1    GFDF01004130    JAV09954.1    AB079859    AB090307    BAB85190.1    KQ976408    KYM91237.1    GECU01014265    JAS93441.1    GDHF01023376    GDHF01011011    JAI28938.1    JAI41303.1    KK852768    KDR16944.1    GALA01000809    JAA94043.1    CVRI01000054    CRK99926.1    ACPB03015317    ACPB03015318    ACPB03015319    ACPB03015320    ACPB03015321    ACPB03015322    GAHY01002295    JAA75215.1    AAZX01004442    AAZX01009262    AAZX01009635    AAZX01016146    AAZX01019615    KU932223    APA33859.1    KQ979302    KYN21981.1    GECZ01031536    JAS38233.1    KQ981523    KYN40214.1    AGBW02013811    OWR42738.1    GBYB01000334    JAG70101.1    GAKP01013330    GAKP01013327    JAC45625.1    KQ982753    KYQ51223.1    GAMC01004527    GAMC01004526    JAC02030.1    CCAG010016470    EZ424344    ADD20620.1    GBXI01005331    GBXI01000379    JAD08961.1    JAD13913.1    GFDG01001807    JAV16992.1    GDHF01018716    GDHF01015239    JAI33598.1    JAI37075.1    QOIP01000002    RLU25654.1    FX986029    BBF97986.1    AF132154    AE013599    AAD34742.1    AAF46726.1    GAMC01004525    JAC02031.1    GAKP01013324    JAC45628.1    KA646067    AFP60696.1    JRES01000440    KNC31138.1    BT012468    AAS93739.1    CH933808    KRG04633.1    CH902619    EDV36159.1    EDW09361.2    CM002911    KMY95549.1    KQ976885    KYN07388.1    OUUW01000001    SPP75373.1    CH940648    EDW61916.1    CH954179    EDV55458.2    CH480824    EDW56631.1    CM000362    EDX08073.1    CM000158    EDW91244.2    AF132555    AAD27854.2    GBXI01002416    JAD11876.1    GFDG01000229    JAV18570.1    CH963846    EDW72392.1    KU663631    APD15625.1    JR050243    AEY61210.1    AFH08201.1    CP012524    ALC42697.1    CM000071    EAL26285.2    CH479183    EDW35877.1    KRG04634.1    KPU76044.1    KRG04632.1    KRF80336.1    KMY95545.1    KRJ99732.1    CH916367    EDW02150.1    KZ288366    PBC26833.1    KY563426    ARK19835.1    UFQS01001585    UFQS01002692    UFQT01001585    UFQT01002692    SSX11498.1    SSX14547.1    SSX31065.1    GDHC01008788    JAQ09841.1    GBHO01033154    GBHO01015329    GBHO01015328    GBHO01004921    GBHO01004918    JAG10450.1    JAG28275.1    JAG28276.1    JAG38683.1    JAG38686.1    KRT02964.1    GEDC01024575    JAS12723.1    ABLF02013510    ABLF02013511    GGMS01006133    MBY75336.1    GFXV01003799    MBW15604.1    DS235817    EEB17633.1    GGMR01016065    MBY28684.1    KQ459594    KPI96193.1    SPP75372.1    GEZM01047513    JAV76821.1   

Proteomes

UP000076408    UP000192223    UP000008820    UP000007062    UP000075884    UP000007266    + More
UP000075840    UP000078540    UP000027135    UP000183832    UP000015103    UP000002358    UP000078492    UP000078541    UP000007151    UP000075809    UP000092444    UP000095300    UP000279307    UP000000803    UP000095301    UP000037069    UP000009192    UP000007801    UP000078542    UP000268350    UP000008792    UP000008711    UP000001292    UP000000304    UP000002282    UP000192221    UP000007798    UP000092553    UP000001819    UP000008744    UP000001070    UP000242457    UP000007819    UP000009046    UP000053268   

PRIDE

Q8T109    Q6NL72    Q9XZ54   

Pfam

PF13499   EF-hand_7        + More
PF00254   FKBP_C
PF13202   EF-hand_5
PF13833   EF-hand_8

Interpro

IPR018247   EF_Hand_1_Ca_BS        + More
IPR011992   EF-hand-dom_pair       
IPR002048   EF_hand_dom       
IPR001179   PPIase_FKBP_dom       

SUPFAM

SSF47473   SSF47473       

CDD

cd00051  EFh

ProteinModelPortal

S4PG11   L0GGU3   A0A220K8J7   I4DIM0   I4DLY3   J3JZ98   + More
A0A182Y995   A0A1W4WGT9   T1DNF6   A0A2M3Z9P5   A0A2M4BZI1   A0A1Q3FV17   A0A2M4DQJ0   A0A2M4AGG7   Q17D71   A0A023EIK3   Q7Q835   L0AT90   A0A182NZ07   A0A023EJR0   D6WID8   A0A2C9GQ82   A0A1B6LS89   A0A1L8DU55   Q8T109   A0A195BV65   A0A1B6J2N5   A0A0K8UQZ9   A0A067RDM7   T1E2D9   A0A1J1ILH6   R4G3D6   K7J7N8   A0A1I9WL39   A0A151JAE4   A0A1B6EJZ3   A0A195FJN6   A0A212EMM7   A0A0C9QAU9   A0A034VUV5   A0A151WTQ4   W8CBT8   D3TSE2   A0A1I8PQR6   A0A0A1XDE5   A0A1L8EE53   A0A0K8VEV8   A0A3L8DYY5   A0A348G6B3   Q9V3V2   W8BLS7   A0A034VVT0   T1PBE6   A0A0L0CFE3   Q6NL72   A0A0Q9XAU1   B3MC59   B4KRE5   A0A0J9RJD1   A0A195D3B1   A0A3B0J637   B4LLG4   B3NMW4   B4I7Q6   B4QG37   B4P8Z0   Q9XZ54   A0A0A1XLL2   A0A1L8EIJ9   A0A1W4VY64   B4MJV3   A0A1J0M5H2   V9IJH7   A0A0B4K7C5   A0A0M4EIP6   Q28XN1   B4GHA7   A0A0Q9XFJ7   A0A0N8P038   A0A0Q9XL14   A0A0Q9WIS7   A0A0J9U7Q3   A0A0R1DRF0   B4J7K2   A0A1W4W934   A0A2A3E4Z8   A0A1W6EVW0   A0A336MMX6   A0A146LPM4   A0A0A9X018   A0A0R3NPR0   A0A1B6CH61   J9JT30   A0A2S2QC67   A0A2H8TN45   E0VW77   A0A2S2PH04   A0A194PT98   A0A3B0J6E6   A0A1Y1LUW0  

PDB

4MSP     E-value=1.94841e-38,     Score=396

KEGG

100141467    K09577 FK506-binding protein 14 [EC:5.2.1.8] | (RefSeq) Fkbp13, Bmfkbp13; FK506-binding protein

GO

GO:0005509   GO:0003755   GO:0016021   GO:0022416   GO:0007444   GO:0008587   GO:0045747   GO:0046716   GO:0005615   GO:0005783   GO:0012505   GO:0006457   GO:0006886   GO:0016020   GO:0016192   GO:0031251   GO:0004672   GO:0003707   GO:0007169  

SignalP

Position:   1 - 19,         Likelihood:  0.998582

 

 

Length:

216

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.42743

Exp number, first 60 AAs:

0.42723

Total prob of N-in:

0.07370

outside

1  -  216

 

 

Pi

17.138432

Theta

16.315066

Tajima's D

-1.095597

CLR

0.093221

CSRT

0.117794110294485

Interpretation

Uncertain