Gene

KWMTBOMO00159

Pre Gene Modal

BGIBMGA002151

Annotation

PREDICTED:_peptidylprolyl_isomerase_isoform_X1_[Bombyx_mori]

Location

Bomo_Chr1(+):5023367-5028734      View in EpiBrowser

Full name

Peptidyl-prolyl cis-trans isomerase      

Location in the cell

Cytoplasmic   Reliability : 1.737 Mitochondrial   Reliability : 1.466

CDS

ATGGGAAAAATTATGTTGGAAATGTATTGGAAACATGCACCTTTGACATGCAGAAATTTTATGGAATTGGTACGTCGAGGCTATTACAACAACACTAAATTTCATCGAGTTATTCGAGATTTCATGATTCAAGGTGGTGATCCAACTGGAACAGGAAAAGGAGGACAATCAATATATGGACCACACTTTAAAGATGAAATAACATCAGATTTAAAACATGCTGGTGCAGGTATATTGTCTATGGCTAATGCTGGTCCTAATACAAACGCATCACAGTTTTTTATAACATTGGCTCCAACACAATGGCTTGATGGTAAACATACGATTTTTGGCAGAGTGCAAAACGGAATGACTGTTGTCAAGAGAATTGGGTTAGTAGAGTGTGATAAAAATGATTGCCCCGTAGACGATGTTCGAATAGAAAGAGCCTACATTCCGAAATAG

Protein

MGKIMLEMYWKHAPLTCRNFMELVRRGYYNNTKFHRVIRDFMIQGGDPTGTGKGGQSIYGPHFKDEITSDLKHAGAGILSMANAGPNTNASQFFITLAPTQWLDGKHTIFGRVQNGMTVVKRIGLVECDKNDCPVDDVRIERAYIPK

Description

PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

Catalytic Activity

[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)

Similarity

Belongs to the cyclophilin-type PPIase family.

Uniprot

H9IY18   Q1HQ20   S4NXX0   A0A212FHK5   A0A2A4K5I3   A0A194RN41   + More
A0A2H1WCG3   A0A0L7LGD7   A0A0P4W0V4   R4G8C5   A0A224XYA0   A0A023F9F9   K1QCT3   A0A069DNN2   A0A067QW70   A0A146M205   A0A0J7KV80   A0A2R7WQC9   A0A0K8SBB5   A0A0A9XI49   A0A1B6GPB1   A0A0L7R2E0   A0A210QWX4   E9J9P4   A0A1B6IPY7   A0A026W290   A0A1B6KNM9   K7IW09   A0A1Y0F4M0   D6WGJ8   A0A195EX83   A0A1B6KHK8   A0A1W4X3M8   A0A232FCT6   F4WV43   A0A195BS39   A0A158NNQ1   A0A1B6EDR7   A0A1X9WEL0   D3WFS4   E2A3G4   A0A1B0DLL9   R7TYX0   E2C8X0   A0A0N0BKZ4   A0A1Y1LYH7   A0A2A3E326   A0A034VZB4   A0A151IA15   W8CB95   A0A084WIC9   A0A0L0BV33   A0A195DT02   A0A2H8TY61   E0VVG7   A0A2S2PE40   A0A0C9QDI2   A0A182Y1J9   A0A0T6B6K0   T1GYP4   A0A2M4C2F3   A0A182PY97   A0A1I8N190   A0A0K8WAW2   A0A2C9JIF8   A0A151WU71   A0A2C9JID6   A0A1L8DUG0   A0A154PFN0   A0A3F2Z245   A0NGJ9   A0A182HQA8   A0A182UET0   Q173P2   A0A3B0JRU0   A0A1B0EYL0   A0A2T7NUI6   A0A1W4VNG6   A0A182MTP6   Q29FF4   B4H1E4   B3M8I0   B4PC71   Q9W0Q2   B3NEQ9   A0A2S2QPL2   B4MXU0   B4HVG9   B4QFC7   C4WX72   A0A1S4ED82   W5JAH9   A0A3Q0J1D8   A0A1A9WBT2   B0X350   A0A1Q3F5H7   A0A3Q0IW80   A0A1A9YRV4   A0A1B0AVP8   A0A1I8Q9Z7  

EC Number

5.2.1.8

Pubmed

19121390    23622113    22118469    26354079    26227816    27129103    + More
25474469    22992520    26334808    24845553    26823975    25401762    28812685    21282665    24508170    30249741    20075255    18362917    19820115    28648823    21719571    21347285    20147296    20798317    23254933    28004739    25348373    24495485    24438588    26108605    20566863    25244985    25315136    15562597    12364791    14747013    17210077    17510324    15632085    17994087    17550304    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    26109357    26109356    22936249    20920257    23761445   

EMBL

BABH01016036    DQ443232    ABF51321.1    GAIX01011987    JAA80573.1    AGBW02008503    + More
OWR53196.1    NWSH01000159    PCG78942.1    KQ460152    KPJ17416.1    ODYU01007721    SOQ50753.1    JTDY01001227    KOB74475.1    GDKW01001268    JAI55327.1    GAHY01001212    JAA76298.1    GFTR01002866    JAW13560.1    GBBI01000580    JAC18132.1    JH816459    EKC31793.1    GBGD01003211    JAC85678.1    KK853182    KDR10176.1    GDHC01004808    JAQ13821.1    LBMM01002905    KMQ94203.1    KK855275    PTY21784.1    GBRD01015249    JAG50577.1    GBHO01026834    JAG16770.1    GECZ01005497    JAS64272.1    KQ414666    KOC65004.1    NEDP02001463    OWF53224.1    GL769399    EFZ10459.1    GECU01018727    JAS88979.1    KK107485    QOIP01000006    EZA50113.1    RLU21985.1    GEBQ01026937    JAT13040.1    KY765621    ARU12143.1    KQ971321    EFA00572.1    KQ981953    KYN32512.1    GEBQ01029068    JAT10909.1    NNAY01000450    OXU28303.1    GL888384    EGI61931.1    KQ976417    KYM89847.1    ADTU01021714    GEDC01001268    JAS36030.1    KY785190    ARS01452.1    GU046313    ADC80507.1    GL436428    EFN72028.1    AJVK01072089    AMQN01011485    KB308897    ELT96155.1    GL453744    EFN75588.1    KQ435689    KOX81292.1    GEZM01043995    JAV78593.1    KZ288458    PBC25501.1    GAKP01010306    JAC48646.1    KQ978260    KYM95875.1    GAMC01005036    JAC01520.1    ATLV01023929    KE525347    KFB49973.1    JRES01001294    KNC23876.1    KQ980530    KYN15649.1    GFXV01006283    MBW18088.1    DS235811    EEB17373.1    GGMR01015104    MBY27723.1    GBYB01012498    JAG82265.1    LJIG01009734    KRT82487.1    CAQQ02189998    GGFJ01010359    MBW59500.1    GDHF01003996    JAI48318.1    KQ982745    KYQ51384.1    GFDF01004179    JAV09905.1    KQ434893    KZC10645.1    AAAB01008986    EAU75759.1    APCN01003304    CH477418    EAT41295.1    OUUW01000009    SPP84837.1    AJWK01019210    PZQS01000009    PVD24821.1    AXCM01001727    CH379067    EAL31301.2    CH479202    EDW30121.1    CH902618    EDV38915.1    CM000159    EDW92726.1    AE014296    AY070975    AAF47391.1    AAL48597.1    CH954178    EDV50054.1    GGMS01010475    MBY79678.1    CH963876    EDW76859.1    CH480817    EDW49934.1    CM000362    CM002912    EDX07037.1    KMY96688.1    ABLF02021598    ABLF02021599    ABLF02021601    AK342483    BAH72492.1    ADMH02002043    ETN59794.1    DS232308    EDS39552.1    GFDL01012266    JAV22779.1    JXJN01004352   

Proteomes

UP000005204    UP000007151    UP000218220    UP000053240    UP000037510    UP000005408    + More
UP000027135    UP000036403    UP000053825    UP000242188    UP000053097    UP000279307    UP000002358    UP000007266    UP000078541    UP000192223    UP000215335    UP000007755    UP000078540    UP000005205    UP000000311    UP000092462    UP000014760    UP000008237    UP000053105    UP000242457    UP000078542    UP000030765    UP000037069    UP000078492    UP000009046    UP000076408    UP000015102    UP000075885    UP000095301    UP000076420    UP000075809    UP000076502    UP000076407    UP000007062    UP000075840    UP000075902    UP000008820    UP000268350    UP000092461    UP000245119    UP000192221    UP000075883    UP000001819    UP000008744    UP000007801    UP000002282    UP000000803    UP000008711    UP000007798    UP000001292    UP000000304    UP000007819    UP000079169    UP000000673    UP000091820    UP000002320    UP000092443    UP000092460    UP000095300   

PRIDE

H9IY18    Q1HQ20   

Pfam

PF00160   Pro_isomerase

Interpro

IPR029000   Cyclophilin-like_dom_sf        + More
IPR020892   Cyclophilin-type_PPIase_CS       
IPR024936   Cyclophilin-type_PPIase       
IPR002130   Cyclophilin-type_PPIase_dom       

SUPFAM

SSF50891   SSF50891       

Gene 3D

2.40.100.10    

ProteinModelPortal

H9IY18   Q1HQ20   S4NXX0   A0A212FHK5   A0A2A4K5I3   A0A194RN41   + More
A0A2H1WCG3   A0A0L7LGD7   A0A0P4W0V4   R4G8C5   A0A224XYA0   A0A023F9F9   K1QCT3   A0A069DNN2   A0A067QW70   A0A146M205   A0A0J7KV80   A0A2R7WQC9   A0A0K8SBB5   A0A0A9XI49   A0A1B6GPB1   A0A0L7R2E0   A0A210QWX4   E9J9P4   A0A1B6IPY7   A0A026W290   A0A1B6KNM9   K7IW09   A0A1Y0F4M0   D6WGJ8   A0A195EX83   A0A1B6KHK8   A0A1W4X3M8   A0A232FCT6   F4WV43   A0A195BS39   A0A158NNQ1   A0A1B6EDR7   A0A1X9WEL0   D3WFS4   E2A3G4   A0A1B0DLL9   R7TYX0   E2C8X0   A0A0N0BKZ4   A0A1Y1LYH7   A0A2A3E326   A0A034VZB4   A0A151IA15   W8CB95   A0A084WIC9   A0A0L0BV33   A0A195DT02   A0A2H8TY61   E0VVG7   A0A2S2PE40   A0A0C9QDI2   A0A182Y1J9   A0A0T6B6K0   T1GYP4   A0A2M4C2F3   A0A182PY97   A0A1I8N190   A0A0K8WAW2   A0A2C9JIF8   A0A151WU71   A0A2C9JID6   A0A1L8DUG0   A0A154PFN0   A0A3F2Z245   A0NGJ9   A0A182HQA8   A0A182UET0   Q173P2   A0A3B0JRU0   A0A1B0EYL0   A0A2T7NUI6   A0A1W4VNG6   A0A182MTP6   Q29FF4   B4H1E4   B3M8I0   B4PC71   Q9W0Q2   B3NEQ9   A0A2S2QPL2   B4MXU0   B4HVG9   B4QFC7   C4WX72   A0A1S4ED82   W5JAH9   A0A3Q0J1D8   A0A1A9WBT2   B0X350   A0A1Q3F5H7   A0A3Q0IW80   A0A1A9YRV4   A0A1B0AVP8   A0A1I8Q9Z7  

PDB

1XWN     E-value=5.86896e-54,     Score=527

KEGG

733108    K12733 peptidyl-prolyl cis-trans isomerase-like 1 [EC:5.2.1.8] | (RefSeq) peptidylprolyl isomerase

PATHWAY

03040    Spliceosome - Bombyx mori (domestic silkworm)

GO

GO:0003755   GO:0006457   GO:0016021   GO:0000413   GO:0005634   GO:0071013   GO:0000398   GO:0071011   GO:0016020   GO:0043565   GO:0043401   GO:0003677   GO:0003707   GO:0007169  

Length:

147

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.00895999999999999

Exp number, first 60 AAs:

0.0002

Total prob of N-in:

0.14017

outside

1  -  147

 

 

Pi

0.432462

Theta

12.16243

Tajima's D

-2.293198

CLR

18.569262

CSRT

0.00294985250737463

Interpretation

Possibly Positive selection