Gene

KWMTBOMO00139

Pre Gene Modal

BGIBMGA002142

Annotation

PREDICTED:_arf-GAP_with_Rho-GAP_domain?_ANK_repeat_and_PH_domain-containing_protein_2_[Bombyx_mori]

Location

Bomo_Chr1(+):4345659-4360131      View in EpiBrowser

Location in the cell

Mitochondrial   Reliability : 1.559 Nuclear   Reliability : 1.724

CDS

ATGCTTAAACCTTGTGGAAGTCTCACTGAGGGCATATACCGTCGAGCGGGTAGCAGTTCAGTATTGTCTGAGCTGCTCGCCAGGTTCAGGAGGGACTCGTGGTCGGTCCAGTTGAGTCCCGGTCAACATTCGGAGCACGACGTCGCCGGTGTACTAAAAAGATTCTTCAGGGATCTACCAGAGTCACTTATACCTAAGGACAATCATCAGGTTCTGATCGGCGCGCTCGAAATGAAAGATGAGACGTCCCGCCACGCGGAGTACCGCCGTGTGATGTCGTCCCTATCCCTGGTCCCTCGGAACACGGCCCGGAAGTTGTTCGCTCATCTACATTTCCTGCACACGATGTCGCACGCGAATAAAATGGGCGCAGAAAATTTGGCTTCCGTTTGGGCGCCCACAATAATGCCGACCGCTTTGACGAGCAACAATTTGCAAACTGCCTGGTCGTCGAAAGAGGTGCTAGTCGTTAGAGATCTGATCGCGAACTTCGAAGCAATATGGGAGCCTACTGAAGCGGAGAAGAGACGCGAGGCGGCCGTCAGGAGAGTACTGATGAGGGTGCTGAGTAATTCAGCTCCGGCGCCGCACAGGGCCGCTGGCGACCTCAAGGCCTGGATCCACGTGAACGACAGGAGTCAGTGCTATCAAGTGGCGCTCACCCCTAACAAGACGAGCTCCGACGTATGCATAGAGCTGTGCGAGAAGGCCAAAACCGAATCGCATCTGCTGATGCTCGAAGAGGTTGTGTGTAACGAGTCGATGCGTCGTATAGTGCACATTGACGAGATCGTACTAGACGTGGTGCTCAGGTGGGGGTATTGGGACGAGGACGACAGAAAGGATAATTATTTGCTGGTGAGAGATAATAAAACGCTTCAGGATATGGATTCGTTGAGACAGACCACGTCGCTTGTGTGCGGCGAAATGAGGTTCGCAAATGAATCGATGAAGACATTCAAACAGCACATGTTCGAGCTGCAGAATAGATGCTTGTGTTACTTCAAAGATAAACAGGGTTCGCAGAAAATCGAAGAATGGAACGTCAAAGATATCCTATGGTACATCGGCCACGAACCGAAACGTAATCCACAAACCCGTTGGGCGATCACCTTTATACCGAGGAATAAAGAAAAAAGGAGCAAAGAGAAACCGTGGTTCGGTAAGACAATAGCCGGCGCGGTAACGGAAGATCAACTAAAGTGGATGTCGGCACTGATGTTCGCCGAGCACACGAGCATACTACCAACGCCTCGACTGGTTATAACATAG

Protein

MLKPCGSLTEGIYRRAGSSSVLSELLARFRRDSWSVQLSPGQHSEHDVAGVLKRFFRDLPESLIPKDNHQVLIGALEMKDETSRHAEYRRVMSSLSLVPRNTARKLFAHLHFLHTMSHANKMGAENLASVWAPTIMPTALTSNNLQTAWSSKEVLVVRDLIANFEAIWEPTEAEKRREAAVRRVLMRVLSNSAPAPHRAAGDLKAWIHVNDRSQCYQVALTPNKTSSDVCIELCEKAKTESHLLMLEEVVCNESMRRIVHIDEIVLDVVLRWGYWDEDDRKDNYLLVRDNKTLQDMDSLRQTTSLVCGEMRFANESMKTFKQHMFELQNRCLCYFKDKQGSQKIEEWNVKDILWYIGHEPKRNPQTRWAITFIPRNKEKRSKEKPWFGKTIAGAVTEDQLKWMSALMFAEHTSILPTPRLVIT

Similarity

Belongs to the GST superfamily.

Uniprot

A0A212F9S2   A0A2H1WGX4   A0A194QZU8   A0A194QAY3   A0A2Z5U7E1   A0A2J7QZA1   + More
A0A1B6MRT4   A0A1B6LEB6   A0A1B6H8G0   A0A1B6IHX6   A0A154PJR1   A0A1B6EQL3   A0A1B6MF42   A0A1B6KCU6   A0A1S4ESY4   A0A0C9R1W2   A0A026WSZ2   A0A3L8DH35   E2B7Q3   A0A195EGC3   A0A151WR18   F4WY92   A0A195AX45   A0A195FEN2   A0A195CBK1   A0A158NHS5   E2AZR0   A0A0J7LBB0   A0A0V0GB74   A0A224XQD9   A0A0L7R9F2   A0A1W4XRT0   E9JB82   A0A0C9PZ76   A0A0P4VHG3   A0A2A3E2V2   A0A088AI97   A0A1Y1L1F6   E0VT06   A0A069DXX1   A0A2S2NUS8   A0A2H8TH91   J9K1U7   A0A2S2QZW1   A0A2R7WM86   D6WE41   A0A0T6B4U2   A0A2P8YAZ8   A0A0N1ITB7   U4UVV5   A0A310SEM9   N6TD68   A0A1B6EDQ8   A0A0C9REQ4   A0A1B0CEA4   A0A1J1HH09   A0A226CXT8   A0A336KS94   U5EDU6   T1PPN4   A0A034VFJ1   A0A034VI84   A0A0P6IVV9   Q17EB0   A0A0K8TX96   A0A0K8VJ81   A0A1I8M272   A0A0L0BT30   W8AB86   A0A182K8D2   A0A1I8Q100   A0A2M3Z3V4   A0A1S4F5Y7   A0A182H3M4   A0A3B0JDC2   A0A2M3ZGM3   A0A182KY66   A0A3B0JZF3   A0A3B0JRL9   A0A0K2U9E3   Q8T3K2   A0A0P9AHP2   B3N0B3   A0A1W4VX72   A0A182FJX9   A0A1W4VJ66   A0A2M4BB80   B4IEV9   A0A0Q5TJ75   B3NWA5   Q0KHR5   A0A0R1EBN8   A0A2M4A3V9   Q9VX92   B4Q244   A0A2M4A3W7   A0A2M4BAU3   A0A0R1EID4   A0A182PTU5  

Pubmed

22118469    26354079    24508170    30249741    20798317    21719571    + More
21347285    21282665    27129103    28004739    20566863    26334808    18362917    19820115    29403074    23537049    25348373    26999592    17510324    25315136    26108605    24495485    26483478    20966253    17994087    18057021    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    17550304   

EMBL

AGBW02009564    OWR50495.1    ODYU01008593    SOQ52318.1    KQ461108    KPJ09116.1    + More
KQ459463    KPJ00581.1    AP017515    BBB06853.1    NEVH01009072    PNF33895.1    GEBQ01001382    JAT38595.1    GEBQ01017961    JAT22016.1    GECU01036747    JAS70959.1    GECU01021177    JAS86529.1    KQ434938    KZC12099.1    GECZ01029535    GECZ01013369    GECZ01009669    GECZ01000977    JAS40234.1    JAS56400.1    JAS60100.1    JAS68792.1    GEBQ01005399    JAT34578.1    GEBQ01030698    JAT09279.1    GBYB01006812    JAG76579.1    KK107109    EZA59170.1    QOIP01000008    RLU19239.1    GL446201    EFN88266.1    KQ978957    KYN27288.1    KQ982813    KYQ50253.1    GL888439    EGI60849.1    KQ976725    KYM76617.1    KQ981636    KYN38858.1    KQ978023    KYM98075.1    ADTU01016037    GL444277    EFN61039.1    LBMM01000040    KMR05197.1    GECL01000862    JAP05262.1    GFTR01006063    JAW10363.1    KQ414627    KOC67459.1    GL770938    EFZ09896.1    GBYB01006808    JAG76575.1    GDKW01003495    JAI53100.1    KZ288462    PBC25469.1    GEZM01070890    JAV66230.1    AAZO01005192    DS235759    EEB16512.1    GBGD01000208    JAC88681.1    GGMR01008285    MBY20904.1    GFXV01001585    MBW13390.1    ABLF02023675    ABLF02023676    ABLF02023677    GGMS01014062    MBY83265.1    KK855086    PTY20743.1    KQ971318    EFA00372.1    LJIG01009871    KRT82213.1    PYGN01000743    PSN41421.1    KQ435828    KOX71878.1    KB632385    ERL94330.1    KQ769940    OAD52745.1    APGK01042753    KB741007    ENN75648.1    GEDC01001222    JAS36076.1    GBYB01006810    JAG76577.1    AJWK01008702    AJWK01008703    AJWK01008704    AJWK01008705    AJWK01008706    AJWK01008707    CVRI01000004    CRK87304.1    LNIX01000048    OXA38142.1    UFQS01000919    UFQT01000919    SSX07664.1    SSX28002.1    GANO01004593    JAB55278.1    KA650023    AFP64652.1    GAKP01017718    JAC41234.1    GAKP01017709    JAC41243.1    GDUN01000807    JAN95112.1    CH477284    EAT44768.1    GDHF01033416    JAI18898.1    GDHF01013392    JAI38922.1    JRES01001383    KNC23235.1    GAMC01021445    JAB85110.1    GGFM01002439    MBW23190.1    JXUM01024585    JXUM01024586    JXUM01024587    JXUM01024588    OUUW01000003    SPP78112.1    GGFM01006945    MBW27696.1    SPP78111.1    SPP78110.1    HACA01016970    CDW34331.1    AY094969    AAM11322.1    CH902640    KPU77360.1    EDV38317.1    KPU77361.1    GGFJ01001100    MBW50241.1    CH480832    EDW46213.1    CH954180    KQS29974.1    EDV46444.1    AE014298    ABI30987.1    CM000162    KRK06827.1    GGFK01002172    MBW35493.1    AAF48686.3    EDX02552.2    GGFK01002124    MBW35445.1    GGFJ01000787    MBW49928.1    KRK06826.1   

Proteomes

UP000007151    UP000053240    UP000053268    UP000235965    UP000076502    UP000079169    + More
UP000053097    UP000279307    UP000008237    UP000078492    UP000075809    UP000007755    UP000078540    UP000078541    UP000078542    UP000005205    UP000000311    UP000036403    UP000053825    UP000192223    UP000242457    UP000005203    UP000009046    UP000007819    UP000007266    UP000245037    UP000053105    UP000030742    UP000019118    UP000092461    UP000183832    UP000198287    UP000008820    UP000095301    UP000037069    UP000075881    UP000095300    UP000069940    UP000268350    UP000075882    UP000007801    UP000192221    UP000069272    UP000001292    UP000008711    UP000000803    UP000002282    UP000075885   

PRIDE

Q8T3K2    Q0KHR5    Q9VX92   

Pfam

PF00620   RhoGAP        + More
PF00169   PH
PF00788   RA
PF13417   GST_N_3
PF13409   GST_N_2
PF00595   PDZ

Interpro

IPR000198   RhoGAP_dom        + More
IPR008936   Rho_GTPase_activation_prot       
IPR001849   PH_domain       
IPR011993   PH-like_dom_sf       
IPR029071   Ubiquitin-like_domsf       
IPR037858   RhoGAP_ARAP       
IPR000159   RA_dom       
IPR005442   GST_omega       
IPR036282   Glutathione-S-Trfase_C_sf       
IPR036249   Thioredoxin-like_sf       
IPR040079   Glutathione_S-Trfase       
IPR010987   Glutathione-S-Trfase_C-like       
IPR004045   Glutathione_S-Trfase_N       
IPR013087   Znf_C2H2_type       
IPR001478   PDZ       
IPR036034   PDZ_sf       

SUPFAM

SSF48350   SSF48350        + More
SSF54236   SSF54236       
SSF47616   SSF47616       
SSF52833   SSF52833       
SSF50156   SSF50156       

Gene 3D

1.10.555.10     2.30.29.30    

CDD

cd04385  RhoGAP_ARAP

ProteinModelPortal

A0A212F9S2   A0A2H1WGX4   A0A194QZU8   A0A194QAY3   A0A2Z5U7E1   A0A2J7QZA1   + More
A0A1B6MRT4   A0A1B6LEB6   A0A1B6H8G0   A0A1B6IHX6   A0A154PJR1   A0A1B6EQL3   A0A1B6MF42   A0A1B6KCU6   A0A1S4ESY4   A0A0C9R1W2   A0A026WSZ2   A0A3L8DH35   E2B7Q3   A0A195EGC3   A0A151WR18   F4WY92   A0A195AX45   A0A195FEN2   A0A195CBK1   A0A158NHS5   E2AZR0   A0A0J7LBB0   A0A0V0GB74   A0A224XQD9   A0A0L7R9F2   A0A1W4XRT0   E9JB82   A0A0C9PZ76   A0A0P4VHG3   A0A2A3E2V2   A0A088AI97   A0A1Y1L1F6   E0VT06   A0A069DXX1   A0A2S2NUS8   A0A2H8TH91   J9K1U7   A0A2S2QZW1   A0A2R7WM86   D6WE41   A0A0T6B4U2   A0A2P8YAZ8   A0A0N1ITB7   U4UVV5   A0A310SEM9   N6TD68   A0A1B6EDQ8   A0A0C9REQ4   A0A1B0CEA4   A0A1J1HH09   A0A226CXT8   A0A336KS94   U5EDU6   T1PPN4   A0A034VFJ1   A0A034VI84   A0A0P6IVV9   Q17EB0   A0A0K8TX96   A0A0K8VJ81   A0A1I8M272   A0A0L0BT30   W8AB86   A0A182K8D2   A0A1I8Q100   A0A2M3Z3V4   A0A1S4F5Y7   A0A182H3M4   A0A3B0JDC2   A0A2M3ZGM3   A0A182KY66   A0A3B0JZF3   A0A3B0JRL9   A0A0K2U9E3   Q8T3K2   A0A0P9AHP2   B3N0B3   A0A1W4VX72   A0A182FJX9   A0A1W4VJ66   A0A2M4BB80   B4IEV9   A0A0Q5TJ75   B3NWA5   Q0KHR5   A0A0R1EBN8   A0A2M4A3V9   Q9VX92   B4Q244   A0A2M4A3W7   A0A2M4BAU3   A0A0R1EID4   A0A182PTU5  

PDB

5JCP     E-value=8.72505e-17,     Score=213

KEGG

101745159    no KO assigned | (RefSeq) arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 2

GO

GO:0007165   GO:0005096   GO:0005547   GO:0004364   GO:0005737   GO:0003676   GO:0043547   GO:0007480   GO:0005794   GO:0043087   GO:0008270   GO:0004190   GO:0006508   GO:0015074   GO:0048013   GO:0005003   GO:0005887   GO:0007169   GO:0016021  

Length:

423

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.00427

Exp number, first 60 AAs:

0.00018

Total prob of N-in:

0.00217

outside

1  -  423

 

 

Pi

24.042402

Theta

20.050466

Tajima's D

-1.491737

CLR

0.210481

CSRT

0.0579471026448678

Interpretation

Uncertain