Gene

KWMTBOMO00103

Pre Gene Modal

BGIBMGA002015

Annotation

PREDICTED:_succinate_dehydrogenase_assembly_factor_3?_mitochondrial_[Plutella_xylostella]

Location

Bomo_Chr1(-):3128547-3163905      View in EpiBrowser

Full name

Succinate dehydrogenase assembly factor 3, mitochondrial       + More
Cysteine dioxygenase      

Location in the cell

Cytoplasmic   Reliability : 1.347 Mitochondrial   Reliability : 1.969

CDS

ATGTCATCACCCGAACATGTGTCGCGGGTTCGCCGGCTCTACAAATTGATCTTCCGGGTTCACCGGGGCTTGCCGCCCGAACTCCGTGTCCTGGGAGACAACTACGCCAGGGACGAGTTCAAGCGACACAAAAAATGTAATAAGGACGAGGCTAAGATTTTTCTCAACGAATGGACGGACTACGCCATTAACCTTGCCAAGCAGATGAAGCCGCTGCACCAAGCCAAGAACAAAATGGTCGGCGGCGTCATCGGAGCCTGA

Protein

MSSPEHVSRVRRLYKLIFRVHRGLPPELRVLGDNYARDEFKRHKKCNKDEAKIFLNEWTDYAINLAKQMKPLHQAKNKMVGGVIGA

Description

Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Promotes maturation of the iron-sulfur protein subunit SdhB of the SDH catalytic dimer, protecting it from the deleterious effects of oxidants.

Catalytic Activity

L-cysteine + O2 = 3-sulfino-L-alanine + H(+)

Cofactor

Fe cation

Subunit

Interacts with SdhB within an SdhA-SdhB subcomplex.

Similarity

Belongs to the complex I LYR family. SDHAF3 subfamily.
Belongs to the cysteine dioxygenase family.

Keywords

Chaperone   Complete proteome   Mitochondrion   Reference proteome   Transit peptide  

Feature

chain  Succinate dehydrogenase assembly factor 3, mitochondrial

Uniprot

H9IXN2   A0A2H1VYT1   A0A2W1C0M8   A0A212F9R6   I4DK21   A0A194QVU9   + More
A0A194Q4T8   A0A1E1WPD3   A0A232F4Q7   K7IV52   A0A2A3E897   A0A0L7LP77   E2B2T3   A0A026WMZ5   E2A5K4   A0A3L8DES3   A0A1S4FG83   A0A195DEM4   A0A1S3DTU4   B0X1Y1   A0A151WY44   Q172I4   A0A195FNK9   A0A1Q3F9M1   A0A182HEU2   A0A0J7NHD2   A0A195CVS9   A0A1B6CLA6   R7UN63   A0A2J7RQ91   A0A0C9QX20   A0A139WFT2   B4M4D3   B4K680   A0A0N0U3A2   A0A067R8H3   B4QX20   A0A1B2AJN1   Q8SZ16   B4PQL1   A0A2S2PB52   K1PRJ9   B3M2T3   A0A336M5K0   B3P135   B4IBU6   A0A1W4UKP6   A0A1B6EK63   B4JFC5   A0A0K2TQI0   B4N664   A0A1Y1NAM9   E0VAE2   A0A3B0JN23   E9H6U3   A0A2S2Q373   A0A1B6J7Q3   A0A1J1IH16   C4WV75   A0A0P5X7N6   A0A164GA42   A0A0P5NY13   A0A1B6MU64   B5DVG5   A0A1B6JZR4   A0A267EJ60   A0A182T500   A0A182YN10   A0A0P4YNJ0   A0A0P5IHW7   A0A0P5B9K6   W8CDR3   A0A0P5QPZ4   A0A1S3H7W1   A0A1I8NI70   A0A0P5DNA4   C1BQS9   B4GFC2   A0A0P4X2S0   A0A034WU70   A0A0C9R2I2   A0A182JXD8   A0A0K8WEG3   A0A0N8ELD8   A0A0L7R6K7   A0A1I8QFE9   A0A0R3STB6   A0A2Y9D194   A0A182XJE0   A0NG50   A0A182I0W5   A0A0A9YDQ3   A0A182VSS5   A0A182RAE9   A0A182MK21   A0A1B0GDG4   A0A1A9UIK1   A0A1A9ZHV6   A0A0B7A3T3   A0A1W4X2L2  

EC Number

1.13.11.20

Pubmed

19121390    28756777    22118469    22651552    26354079    28648823    + More
20075255    26227816    20798317    24508170    30249741    17510324    26483478    23254933    18362917    19820115    17994087    24845553    10731132    12537572    12537569    24954417    17550304    22992520    28004739    20566863    21292972    15632085    25244985    24495485    25315136    25348373    20966253    12364791    14747013    17210077    25401762   

EMBL

BABH01015863    ODYU01005124    SOQ45682.1    KZ149901    PZC78516.1    AGBW02009564    + More
OWR50474.1    AK401639    BAM18261.1    KQ461108    KPJ09090.1    KQ459463    KPJ00557.1    GDQN01002141    JAT88913.1    NNAY01000950    OXU25761.1    AAZX01007538    KZ288326    PBC27977.1    JTDY01000423    KOB77257.1    GL445235    EFN89998.1    KK107148    EZA57442.1    GL436993    EFN71287.1    QOIP01000009    RLU18389.1    KQ980934    KYN11326.1    DS232274    EDS38911.1    KQ982652    KYQ52808.1    CH477436    EAT40942.1    KQ981382    KYN42140.1    GFDL01010832    JAV24213.1    JXUM01036159    KQ561085    KXJ79760.1    LBMM01005007    KMQ91920.1    KQ977279    KYN04264.1    GEDC01023068    GEDC01008935    GEDC01005562    JAS14230.1    JAS28363.1    JAS31736.1    AMQN01006894    KB299468    ELU07974.1    NEVH01001345    PNF42998.1    GBYB01000235    JAG70002.1    KQ971351    KYB26786.1    CH940652    EDW59494.1    CH933806    EDW14130.1    KQ435896    KOX69328.1    KK852811    KDR15889.1    CM000364    EDX12674.1    KX531340    ANY27150.1    AE014297    AY071188    CM000160    EDW97307.1    GGMR01014064    MBY26683.1    JH816424    EKC21454.1    CH902617    EDV43463.1    UFQT01000186    SSX21308.1    CH954181    EDV49154.1    CH480827    EDW44854.1    GECZ01031466    JAS38303.1    CH916369    EDV93406.1    HACA01010704    CDW28065.1    CH964154    EDW79853.1    GEZM01013315    GEZM01013313    JAV92667.1    DS235005    EEB10348.1    OUUW01000007    SPP83624.1    GL732598    EFX72572.1    GGMS01002933    MBY72136.1    GECU01026791    GECU01012518    JAS80915.1    JAS95188.1    CVRI01000048    CRK98836.1    ABLF02037413    AK341389    BAH71795.1    GDIP01076217    JAM27498.1    LRGB01016081    KZR98715.1    GDIQ01146148    JAL05578.1    GEBQ01000520    JAT39457.1    CM000070    EDY68311.1    GECU01003333    JAT04374.1    NIVC01002109    PAA60812.1    GDIP01226252    JAI97149.1    GDIQ01216176    JAK35549.1    GDIP01188354    JAJ35048.1    GAMC01001498    GAMC01001496    JAC05060.1    GDIQ01114008    JAL37718.1    GDIP01153598    JAJ69804.1    BT076958    ACO11382.1    CH479182    EDW34307.1    GDIP01247224    JAI76177.1    GAKP01001237    JAC57715.1    GBYB01007052    JAG76819.1    GDHF01002751    JAI49563.1    GDIQ01015364    JAN79373.1    KQ414646    KOC66510.1    UYSG01011113    VDL60948.1    AAAB01008980    EAU76145.2    APCN01005279    GBHO01012402    GBRD01010890    JAG31202.1    JAG54934.1    AXCM01000163    CCAG010011880    HACG01027851    CEK74716.1   

Proteomes

UP000005204    UP000007151    UP000053240    UP000053268    UP000215335    UP000002358    + More
UP000242457    UP000037510    UP000008237    UP000053097    UP000000311    UP000279307    UP000078492    UP000079169    UP000002320    UP000075809    UP000008820    UP000078541    UP000069940    UP000249989    UP000036403    UP000078542    UP000014760    UP000235965    UP000007266    UP000008792    UP000009192    UP000053105    UP000027135    UP000000304    UP000000803    UP000002282    UP000005408    UP000007801    UP000008711    UP000001292    UP000192221    UP000001070    UP000007798    UP000009046    UP000268350    UP000000305    UP000183832    UP000007819    UP000076858    UP000001819    UP000215902    UP000075901    UP000076408    UP000085678    UP000095301    UP000008744    UP000075881    UP000053825    UP000095300    UP000046397    UP000274504    UP000075882    UP000076407    UP000007062    UP000075840    UP000075920    UP000075900    UP000075883    UP000092444    UP000078200    UP000092445    UP000192223   

PRIDE

H9IXN2    Q8SZ16   

Pfam

PF00069   Pkinase        + More
PF05995   CDO_I

Interpro

IPR008381   SDHAF3/Sdh7        + More
IPR011009   Kinase-like_dom_sf       
IPR008271   Ser/Thr_kinase_AS       
IPR000719   Prot_kinase_dom       
IPR039121   NUDT19       
IPR000086   NUDIX_hydrolase_dom       
IPR015797   NUDIX_hydrolase-like_dom_sf       
IPR011051   RmlC_Cupin_sf       
IPR014710   RmlC-like_jellyroll       
IPR010300   CDO_1       

SUPFAM

SSF56112   SSF56112        + More
SSF55811   SSF55811       
SSF51182   SSF51182       

Gene 3D

2.60.120.10    

ProteinModelPortal

H9IXN2   A0A2H1VYT1   A0A2W1C0M8   A0A212F9R6   I4DK21   A0A194QVU9   + More
A0A194Q4T8   A0A1E1WPD3   A0A232F4Q7   K7IV52   A0A2A3E897   A0A0L7LP77   E2B2T3   A0A026WMZ5   E2A5K4   A0A3L8DES3   A0A1S4FG83   A0A195DEM4   A0A1S3DTU4   B0X1Y1   A0A151WY44   Q172I4   A0A195FNK9   A0A1Q3F9M1   A0A182HEU2   A0A0J7NHD2   A0A195CVS9   A0A1B6CLA6   R7UN63   A0A2J7RQ91   A0A0C9QX20   A0A139WFT2   B4M4D3   B4K680   A0A0N0U3A2   A0A067R8H3   B4QX20   A0A1B2AJN1   Q8SZ16   B4PQL1   A0A2S2PB52   K1PRJ9   B3M2T3   A0A336M5K0   B3P135   B4IBU6   A0A1W4UKP6   A0A1B6EK63   B4JFC5   A0A0K2TQI0   B4N664   A0A1Y1NAM9   E0VAE2   A0A3B0JN23   E9H6U3   A0A2S2Q373   A0A1B6J7Q3   A0A1J1IH16   C4WV75   A0A0P5X7N6   A0A164GA42   A0A0P5NY13   A0A1B6MU64   B5DVG5   A0A1B6JZR4   A0A267EJ60   A0A182T500   A0A182YN10   A0A0P4YNJ0   A0A0P5IHW7   A0A0P5B9K6   W8CDR3   A0A0P5QPZ4   A0A1S3H7W1   A0A1I8NI70   A0A0P5DNA4   C1BQS9   B4GFC2   A0A0P4X2S0   A0A034WU70   A0A0C9R2I2   A0A182JXD8   A0A0K8WEG3   A0A0N8ELD8   A0A0L7R6K7   A0A1I8QFE9   A0A0R3STB6   A0A2Y9D194   A0A182XJE0   A0NG50   A0A182I0W5   A0A0A9YDQ3   A0A182VSS5   A0A182RAE9   A0A182MK21   A0A1B0GDG4   A0A1A9UIK1   A0A1A9ZHV6   A0A0B7A3T3   A0A1W4X2L2  

KEGG

101736161    no KO assigned | (RefSeq) succinate dehydrogenase assembly factor 3, mitochondrial

GO

GO:0005739   GO:0034553   GO:0005524   GO:0004672   GO:0016021   GO:0016787   GO:0006105   GO:0005758   GO:0050881   GO:0006979   GO:0055093   GO:0005759   GO:0042412   GO:0005506   GO:0017172  

PANTHER

PTHR13137   PTHR12318   PTHR12918  

Subcellular location

Mitochondrion matrix  

Length:

86

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.0002

Exp number, first 60 AAs:

0.0002

Total prob of N-in:

0.21942

outside

1  -  86

 

 

Pi

2.258291

Theta

3.909269

Tajima's D

-2.083699

CLR

0.043009

CSRT

0.00649967501624919

Interpretation

Possibly Positive selection