Gene

KWMTBOMO00096

Pre Gene Modal

BGIBMGA002017

Annotation

abnormal_chemosensory_jump_6?_splice_form_A?_partial_[Bombyx_mori]

Location

Bomo_Chr1(-):2765638-2766766      View in EpiBrowser

Full name

POU domain protein       + More
Inhibitory POU protein      

Alternative Name

Abnormal chemosensory jump 6 protein

Transcription factor

Pou

Location in the cell

Nuclear   Reliability : 4.083

CDS

ATGGGTCACCACGGAATGGAAGGGATCGACATGCTCGATCCGCTGACTTCGTCCTCTATGACCACACTGGCGCCGATGGGCGAAGGCGCACCACCACATCACCAGCTCCACGGCTATGGCGCAATGAACCACGTTATGAACCATCACCACCACCCCGGCGGGCTCGGACACGCACCTCCCGCGCACCTAGGACACCCCGCTGCTGCACTACATCCCGATACTGACACAGATCCTCGAGAACTCGAAGCCTTCGCTGAACGATTCAAACAGAGACGGATCAAACTCGGCGTCACACAAGCGGACGTCGGCAAAGCGCTTGCGAATTTGAAACTGCCAGGAGTGGGGGCGCTCTCGCAGAGCACGATCTGTCGCTTCGAAAGTCTAACGCTCAGTCACAATAATATGATTGCTCTCAAACCCATACTGCAGGCGTGGCTCGAGGAAGCGGAAGCGCAGGCCAAGAACAAGAGACGGGACCCGGACGCGCCAAGCGTCCTGCCGGCTGGCGAAAAGAAACGCAAGAGGACATCCATAGCGGCACCGGAGAAACGAAGTCTAGAAGCGTACTTTGCAGTCCAGCCGAGGCCTTCCGGCGAGAAGATAACCGCAATCGCAGAGAAGCTGGACCTCAAAAAGAACGTCGTGAGGGTTTGGTTCTGTAACCAACGACAGAAACAGAAGCGGATGAAGTTCGCGGCGCAACACTGA

Protein

MGHHGMEGIDMLDPLTSSSMTTLAPMGEGAPPHHQLHGYGAMNHVMNHHHHPGGLGHAPPAHLGHPAAALHPDTDTDPRELEAFAERFKQRRIKLGVTQADVGKALANLKLPGVGALSQSTICRFESLTLSHNNMIALKPILQAWLEEAEAQAKNKRRDPDAPSVLPAGEKKRKRTSIAAPEKRSLEAYFAVQPRPSGEKITAIAEKLDLKKNVVRVWFCNQRQKQKRMKFAAQH

Description

Modulates gene transcription; simultaneously generates both a specific activator and an inhibitor of gene transcription, capable of modulating two distinct regulatory programs during neural development. Has a role in olfactory behavior.

Similarity

Belongs to the POU transcription factor family.
Belongs to the POU transcription factor family. Class-4 subfamily.

Keywords

Activator   Alternative splicing   Complete proteome   DNA-binding   Homeobox   Nucleus   Olfaction   Reference proteome   Repressor   Sensory transduction   Transcription   Transcription regulation  

Feature

chain  Inhibitory POU protein
splice variant  In isoform B and isoform C.

Uniprot

H9IXN4   G9M9L9   G3XFY9   A0A2H1WBZ6   G3XFY8   A0A194Q4T9   + More
G3XFY7   G3XFY6   G3XFY5   A0A2A4IYK7   A0A194QZR9   A0A0L7LPG3   A0A2W1BPG4   A0A212F9L6   A0A2Z5U743   A0A336LRW7   T1I7M1   A0A0J7KAA6   A0A2R7VV92   A0A1A9YCG7   A0A1A9VP44   Q179V1   A0A1B0AEH3   E0VT10   A0A182HZP1   B0X5F0   A0A3B0JX34   A0A0M3QZN8   A0A1S3DDW1   A0A1S4FB18   A0A195EM21   A0A026WTR6   B4ILG6   A0A0L0BNB6   A0A182WZJ2   A0A1W4XLI1   A0A1W4XAV5   A0A3L8D956   B4R567   B4JXG1   A0A182NMW2   A0A1W7R5M7   E2BAV5   M9NEH8   M9NDX7   M9NGG0   A0A0P8ZJQ6   A0A1I8Q5N7   M9NDY0   A0A151JTF4   A0A0P9A9R4   B3MR89   P24350   A0A195AU00   A0A0P8XJP6   N6U4V7   D6WEF1   A0A1I8Q5S0   A0A1J1I3N9   U4UMH1   A0A1I8Q5M4   E9IX24   A0A154NW48   A0A151X8P6   A0A158NPZ1   A0A1W4VFT0   B5DMS3   A0A1I8NBD3   A0A151INS7   P24350-1   A0A1W4V3J5   M9NH29   A0A0Q5TIV5   Q0IGS2   A0A1W4VH54   B7Z0Y6   A0A0Q5T501   B4MSQ3   P24350-3   A0A0Q9WIW0   A0A0P8Y703   A0A0P8XJQ4   A0A1W4V405   M9NF66   A0A0Q5T4V3   M9NF61   A0A1W4VGB7   M9NH32   B3NTL9   B4M7U9   A0A0N8NZR5   A0A0P9BTX2   P24350-4   A0A0P8XZU4   A0A0P8XK01   A0A1I8Q5Q0   A0A0A1WNC5   A0A0M9A9N6   A0A1I8Q5M6  

Pubmed

19121390    26354079    26227816    28756777    22118469    17510324    + More
20566863    24508170    17994087    26108605    30249741    20798317    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    1673230    10069339    1346754    8986770    23537049    18362917    19820115    21282665    21347285    15632085    25315136    25830018   

EMBL

BABH01015812    AB635378    BAL15791.1    AB623141    BAL03081.1    ODYU01007336    + More
SOQ50014.1    AB623140    BAL03080.1    KQ459463    KPJ00553.1    AB623139    BAL03079.1    AB623138    BAL03078.1    AB623137    BAL03077.1    NWSH01004509    PCG65027.1    KQ461108    KPJ09086.1    JTDY01000389    KOB77413.1    KZ150037    PZC74620.1    AGBW02009564    OWR50420.1    AP017489    BBB06754.1    UFQS01000065    UFQT01000065    SSW98923.1    SSX19309.1    ACPB03000187    LBMM01010603    KMQ87363.1    KK854109    PTY11416.1    CH477345    EAT43012.1    DS235759    EEB16516.1    APCN01001988    DS232376    EDS40835.1    OUUW01000003    SPP78309.1    CP012528    ALC49743.1    KQ978730    KYN28929.1    KK107105    EZA59455.1    CH480871    EDW53829.1    JRES01001702    KNC20764.1    QOIP01000011    RLU16851.1    CM000366    EDX17968.1    CH916376    EDV95437.1    GEHC01001179    JAV46466.1    GL446860    EFN87183.1    AE014298    AFH07400.1    AFH07398.1    AFH07399.1    CH902622    KPU75062.1    AFH07403.1    KQ982014    KYN30657.1    KPU75056.1    EDV34294.2    X58436    AF086816    AH003854    KQ976745    KYM75459.1    KPU75055.1    APGK01049664    APGK01049665    APGK01049666    APGK01049667    KB741156    ENN73592.1    KQ971318    EFA01306.2    CVRI01000040    CRK94811.1    KB632417    ERL95284.1    GL766616    EFZ14931.1    KQ434769    KZC03782.1    KQ982409    KYQ56704.1    ADTU01022730    ADTU01022731    ADTU01022732    ADTU01022733    ADTU01022734    ADTU01022735    CH379064    EDY73105.2    KQ976914    KYN07130.1    AFH07397.1    CH954180    KQS30315.1    BT028815    BT028848    ABI34229.3    ACL82930.1    KQS30317.1    CH963851    EDW75142.2    CH940653    KRF80827.1    KPU75059.1    KPU75058.1    AFH07401.1    KQS30316.1    AFH07396.1    AFH07402.1    EDV47023.2    EDW62866.2    KPU75060.1    KPU75061.1    KPU75054.1    KPU75057.1    GBXI01014277    JAD00015.1    KQ435720    KOX78699.1   

Proteomes

UP000005204    UP000053268    UP000218220    UP000053240    UP000037510    UP000007151    + More
UP000015103    UP000036403    UP000092443    UP000078200    UP000008820    UP000092445    UP000009046    UP000075840    UP000002320    UP000268350    UP000092553    UP000079169    UP000078492    UP000053097    UP000001292    UP000037069    UP000076407    UP000192223    UP000279307    UP000000304    UP000001070    UP000075884    UP000008237    UP000000803    UP000007801    UP000095300    UP000078541    UP000078540    UP000019118    UP000007266    UP000183832    UP000030742    UP000076502    UP000075809    UP000005205    UP000192221    UP000001819    UP000095301    UP000078542    UP000008711    UP000007798    UP000008792    UP000053105   

PRIDE

H9IXN4    G9M9L9    G3XFY9    G3XFY8    G3XFY7    G3XFY6    + More
G3XFY5    P24350    Q0IGS2   

Pfam

PF00157   Pou        + More
PF00046   Homeodomain

Interpro

IPR009057   Homeobox-like_sf        + More
IPR010982   Lambda_DNA-bd_dom_sf       
IPR001387   Cro/C1-type_HTH       
IPR001356   Homeobox_dom       
IPR000327   POU_dom       
IPR017970   Homeobox_CS       
IPR013847   POU       
IPR015584   POU4-TF1       
IPR032961   POU4F3       

SUPFAM

SSF47413   SSF47413        + More
SSF46689   SSF46689       

CDD

cd00086  homeodomain
cd00093  HTH_XRE

ProteinModelPortal

H9IXN4   G9M9L9   G3XFY9   A0A2H1WBZ6   G3XFY8   A0A194Q4T9   + More
G3XFY7   G3XFY6   G3XFY5   A0A2A4IYK7   A0A194QZR9   A0A0L7LPG3   A0A2W1BPG4   A0A212F9L6   A0A2Z5U743   A0A336LRW7   T1I7M1   A0A0J7KAA6   A0A2R7VV92   A0A1A9YCG7   A0A1A9VP44   Q179V1   A0A1B0AEH3   E0VT10   A0A182HZP1   B0X5F0   A0A3B0JX34   A0A0M3QZN8   A0A1S3DDW1   A0A1S4FB18   A0A195EM21   A0A026WTR6   B4ILG6   A0A0L0BNB6   A0A182WZJ2   A0A1W4XLI1   A0A1W4XAV5   A0A3L8D956   B4R567   B4JXG1   A0A182NMW2   A0A1W7R5M7   E2BAV5   M9NEH8   M9NDX7   M9NGG0   A0A0P8ZJQ6   A0A1I8Q5N7   M9NDY0   A0A151JTF4   A0A0P9A9R4   B3MR89   P24350   A0A195AU00   A0A0P8XJP6   N6U4V7   D6WEF1   A0A1I8Q5S0   A0A1J1I3N9   U4UMH1   A0A1I8Q5M4   E9IX24   A0A154NW48   A0A151X8P6   A0A158NPZ1   A0A1W4VFT0   B5DMS3   A0A1I8NBD3   A0A151INS7   P24350-1   A0A1W4V3J5   M9NH29   A0A0Q5TIV5   Q0IGS2   A0A1W4VH54   B7Z0Y6   A0A0Q5T501   B4MSQ3   P24350-3   A0A0Q9WIW0   A0A0P8Y703   A0A0P8XJQ4   A0A1W4V405   M9NF66   A0A0Q5T4V3   M9NF61   A0A1W4VGB7   M9NH32   B3NTL9   B4M7U9   A0A0N8NZR5   A0A0P9BTX2   P24350-4   A0A0P8XZU4   A0A0P8XK01   A0A1I8Q5Q0   A0A0A1WNC5   A0A0M9A9N6   A0A1I8Q5M6  

PDB

2XSD     E-value=1.19449e-29,     Score=321

KEGG

100750224    K09366 POU domain transcription factor, class 4 | (RefSeq) Bmacj6, GA002017; abnormal chemosensory j

GO

GO:0003700   GO:0043565   GO:0005634   GO:0003714   GO:0007636   GO:0007411   GO:0045944   GO:0050911   GO:0070983   GO:0008039   GO:0003677   GO:0048813   GO:0006355   GO:0005525   GO:0048013   GO:0005003   GO:0005887   GO:0007169   GO:0016021  

PANTHER

PTHR11636:SF42   PTHR11636:SF43  

Subcellular location

Nucleus  

Length:

235

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.00101

Exp number, first 60 AAs:

0.00041

Total prob of N-in:

0.03920

outside

1  -  235

 

 

Pi

13.281409

Theta

8.513356

Tajima's D

1.954733

CLR

0.067102

CSRT

0.883105844707765

Interpretation

Uncertain