Gene

KWMTBOMO00088

Pre Gene Modal

BGIBMGA002111

Annotation

PREDICTED:_enkurin_[Papilio_xuthus]

Location

Bomo_Chr1(+):2537347-2541009      View in EpiBrowser

Full name

Ribosome biogenesis protein WDR12 homolog       + More
Enkurin      

Location in the cell

Cytoplasmic   Reliability : 1.694 Nuclear   Reliability : 1.482

CDS

ATGCTAATACTATTGCTAGTTGACACGAGAGATGGGCACATCAAGAAAATTAAGGGTTCAGGCGAAGTCCCCGAGTATTGCCTCAGACCGGATTTTGGTCGAGTTCCAGAATATTTAGTAAGGCGTAACAGAAAAATCCAGAAGGCTCTCGAAGAGATCAGGCTCGCTGATCAGAACAAGGAGAGCTTGTGCAAGCTTATCAGCGAGGAGGAACGGCAGAAGCTGTTGAAGGATTTGAAGAACAACTGGGAGCTGATGCAAAAAGCGTTTCTTCAGTTGCCGATGCTGACCGATACGATACCGAAAATTTTACGCAAAACAAAAATGGAACAAGAACTCAAGCAGCTCGAGAAAGACATCGCTTTGGTCGAGAGCAATCCTTATATCTACATTTACGAGTGA

Protein

MLILLLVDTRDGHIKKIKGSGEVPEYCLRPDFGRVPEYLVRRNRKIQKALEEIRLADQNKESLCKLISEEERQKLLKDLKNNWELMQKAFLQLPMLTDTIPKILRKTKMEQELKQLEKDIALVESNPYIYIYE

Description

Required for maturation of ribosomal RNAs and formation of the large ribosomal subunit.
Adapter that functions to localize a calcium-sensitive signal transduction machinery in sperm to a calcium-permeable ion channel.

Subunit

Binds calmodulin via its IQ domain. Interacts with TRPC1, TRPC2, TRPC5, but not TRPC3 (By similarity).

Similarity

Belongs to the WD repeat WDR12/YTM1 family.

Keywords

Calmodulin-binding   Cell projection   Cilium   Complete proteome   Flagellum   Reference proteome   SH3-binding  

Feature

chain  Enkurin

Uniprot

H9IXX8   A0A194QAU7   A0A194QUT8   A0A2H1WVK4   A0A2A4JTZ3   A0A2W1BND2   + More
A0A212F9K2   A0A0L7LRU3   A0A182LV73   A0A182QMK2   A0A182J3C0   A0A182T795   Q17DC8   Q17DC7   A0A182G2Q3   A0A182NKR8   A0A084VQX1   A0A182JPM9   A0A1B6EWQ4   A0A1B6G4K5   A0A182YMM7   W5JUU3   A0A182WJQ3   A0A182R3H8   A0A182UYL6   A0A2C9GRR8   A0A182KQP9   Q5TWS7   A0A182U0N4   B0X8F0   A0A1Q3FSR4   A0A182XLL2   A0A1B6HX82   A0A336MZW2   A0A336LRF3   A0A1W4XIH3   A0A182FCH2   E1ZWK9   A0A1B6E8Q5   N6UEM7   U6DHF8   A0A2K5IUP3   A0A2K5W7A7   A0A2K5W7A6   A0A2K6L5S6   A0A2K6PTD6   A0A151XED2   A0A0D9RIA8   A0A195D9S7   A0A2I3RWJ5   A0A2I2Y3P2   A0A2I3HBU0   A0A087WUX1   G7N1R5   A0A2K5IUN0   A0A2K6BG27   G7PEM5   A0A2K6BG02   Q4R9A6   A0A2K6L5S9   A0A2R9BBE8   F4W4Z8   U4UIN1   A0A2K6PTE5   F6VQA4   G3ICY1   A0A091DVG4   M1EMT8   D7EI11   M3YL38   A0A286ZIE6   Q5VV23   G1S493   Q8TC29   E2RR19   A0A2J8SUS4   F7A7P7   G3QL25   A0A3Q0K142   A0A2J8MNI4   A0A2J8MNL1   A0A2K5PCN4   A0A384DQA0   A0A2K5XDA5   A0A1U7UIH1   A0A2U3W768   A0A3P4RWS3   I3MDQ7   A0A2K5MRH9   B5THN4   A0A2R9BA21   A0A2K6SED4   A0A2Y9KCT3   G5AVY5   A0A1A6H8W8   L8HZR9   E1B836   A0A2R8MNP1   A0A2Y9DSY3   A0A0N8JYV0  

Pubmed

19121390    26354079    28756777    22118469    26227816    17510324    + More
26483478    24438588    25244985    20920257    23761445    20966253    12364791    14747013    17210077    20798317    23537049    25362486    16136131    15164054    22002653    15944441    22722832    21719571    19892987    21804562    23236062    18362917    19820115    11181995    15385169    14702039    15489334    16341006    12481130    15114417    24813606    21993625    22751099    19393038   

EMBL

BABH01015783    BABH01015784    KQ459463    KPJ00546.1    KQ461108    KPJ09079.1    + More
ODYU01011323    SOQ56996.1    NWSH01000586    PCG75497.1    KZ149952    PZC76572.1    AGBW02009564    OWR50426.1    JTDY01000228    KOB78188.1    AXCM01002371    AXCN02000542    CH477297    EAT44362.1    EAT44363.1    JXUM01039933    JXUM01039934    KQ561224    KXJ79302.1    ATLV01015338    KE525006    KFB40365.1    GECZ01027323    JAS42446.1    GECZ01012394    JAS57375.1    ADMH02000008    ETN68122.1    APCN01000179    AAAB01008807    EAL41843.3    DS232486    EDS42486.1    GFDL01004394    JAV30651.1    GECU01028461    JAS79245.1    UFQT01004512    SSX35710.1    UFQS01000091    UFQT01000091    SSW99149.1    SSX19531.1    GL434853    EFN74446.1    GEDC01003002    JAS34296.1    APGK01038383    KB740954    ENN77092.1    HAAF01009743    CCP81567.1    AQIA01070383    AQIA01070384    AQIA01070385    AQIA01070386    AQIA01070387    AQIA01070388    AQIA01070389    KQ982254    KYQ58707.1    AQIB01160473    KQ981082    KYN09633.1    AACZ04070749    AACZ04070750    AACZ04070751    NBAG03000250    PNI61085.1    CABD030069631    CABD030069632    CABD030069633    CABD030069634    CABD030069635    CABD030069636    CABD030069637    CABD030069638    CABD030069639    CABD030069640    ADFV01049909    ADFV01049910    ADFV01049911    ADFV01049912    AL512598    CM001261    EHH18942.1    CM001284    EHH64619.1    AB168190    BAE00315.1    AJFE02073497    AJFE02073498    AJFE02073499    GL887596    EGI70694.1    KB632338    ERL92897.1    JH001974    EGW14195.1    KN121889    KFO35087.1    JP009327    AER97924.1    DS497669    EFA12927.1    AEYP01043676    AEYP01043677    AEMK02000074    CH471072    EAW86117.1    AY454125    AK095021    AK292495    BC026165    AAEX03001175    NDHI03003541    PNJ24515.1    EAAA01000006    PNI61086.1    PNI61087.1    PNI61088.1    CYRY02043751    VCX38371.1    AGTP01016586    EU939760    ACH73242.1    JH167180    EHB01196.1    LZPO01044445    OBS74305.1    JH882436    ELR49418.1    JARO02004982    KPP67553.1   

Proteomes

UP000005204    UP000053268    UP000053240    UP000218220    UP000007151    UP000037510    + More
UP000075883    UP000075886    UP000075880    UP000075901    UP000008820    UP000069940    UP000249989    UP000075884    UP000030765    UP000075881    UP000076408    UP000000673    UP000075920    UP000075900    UP000075903    UP000075840    UP000075882    UP000007062    UP000075902    UP000002320    UP000076407    UP000192223    UP000069272    UP000000311    UP000019118    UP000233080    UP000233180    UP000233200    UP000075809    UP000029965    UP000078492    UP000002277    UP000001519    UP000001073    UP000005640    UP000233120    UP000009130    UP000240080    UP000007755    UP000030742    UP000002281    UP000001075    UP000028990    UP000007266    UP000000715    UP000008227    UP000002254    UP000008144    UP000233040    UP000261680    UP000291021    UP000233140    UP000189704    UP000245340    UP000005215    UP000233060    UP000233220    UP000248482    UP000006813    UP000092124    UP000009136    UP000008225    UP000248480    UP000034805    UP000192224   

PRIDE

H9IXX8    A0A087WUX1    F6VQA4    G3ICY1    Q5VV23    Q8TC29    + More

Pfam

PF13864   Enkurin        + More
PF13869   NUDIX_2
PF17862   AAA_lid_3
PF00004   AAA
PF00400   WD40
PF16450   Prot_ATP_ID_OB
PF08154   NLE
PF01423   LSM
PF00096   zf-C2H2

Interpro

IPR026150   Enkur        + More
IPR027012   Enkurin_dom       
IPR015797   NUDIX_hydrolase-like_dom_sf       
IPR000086   NUDIX_hydrolase_dom       
IPR016706   Cleav_polyA_spec_factor_su5       
IPR028599   WDR12/Ytm1       
IPR003959   ATPase_AAA_core       
IPR012972   NLE       
IPR020472   G-protein_beta_WD-40_rep       
IPR001163   LSM_dom_euk/arc       
IPR036322   WD40_repeat_dom_sf       
IPR027417   P-loop_NTPase       
IPR003960   ATPase_AAA_CS       
IPR019775   WD40_repeat_CS       
IPR032501   Prot_ATP_ID_OB       
IPR010920   LSM_dom_sf       
IPR015943   WD40/YVTN_repeat-like_dom_sf       
IPR034102   Sm_D1       
IPR003593   AAA+_ATPase       
IPR041569   AAA_lid_3       
IPR001680   WD40_repeat       
IPR005937   26S_Psome_P45-like       
IPR017986   WD40_repeat_dom       
IPR036236   Znf_C2H2_sf       
IPR013087   Znf_C2H2_type       

SUPFAM

SSF55811   SSF55811        + More
SSF50978   SSF50978       
SSF52540   SSF52540       
SSF50182   SSF50182       
SSF57667   SSF57667       

Gene 3D

2.130.10.10    

CDD

cd01724  Sm_D1

ProteinModelPortal

H9IXX8   A0A194QAU7   A0A194QUT8   A0A2H1WVK4   A0A2A4JTZ3   A0A2W1BND2   + More
A0A212F9K2   A0A0L7LRU3   A0A182LV73   A0A182QMK2   A0A182J3C0   A0A182T795   Q17DC8   Q17DC7   A0A182G2Q3   A0A182NKR8   A0A084VQX1   A0A182JPM9   A0A1B6EWQ4   A0A1B6G4K5   A0A182YMM7   W5JUU3   A0A182WJQ3   A0A182R3H8   A0A182UYL6   A0A2C9GRR8   A0A182KQP9   Q5TWS7   A0A182U0N4   B0X8F0   A0A1Q3FSR4   A0A182XLL2   A0A1B6HX82   A0A336MZW2   A0A336LRF3   A0A1W4XIH3   A0A182FCH2   E1ZWK9   A0A1B6E8Q5   N6UEM7   U6DHF8   A0A2K5IUP3   A0A2K5W7A7   A0A2K5W7A6   A0A2K6L5S6   A0A2K6PTD6   A0A151XED2   A0A0D9RIA8   A0A195D9S7   A0A2I3RWJ5   A0A2I2Y3P2   A0A2I3HBU0   A0A087WUX1   G7N1R5   A0A2K5IUN0   A0A2K6BG27   G7PEM5   A0A2K6BG02   Q4R9A6   A0A2K6L5S9   A0A2R9BBE8   F4W4Z8   U4UIN1   A0A2K6PTE5   F6VQA4   G3ICY1   A0A091DVG4   M1EMT8   D7EI11   M3YL38   A0A286ZIE6   Q5VV23   G1S493   Q8TC29   E2RR19   A0A2J8SUS4   F7A7P7   G3QL25   A0A3Q0K142   A0A2J8MNI4   A0A2J8MNL1   A0A2K5PCN4   A0A384DQA0   A0A2K5XDA5   A0A1U7UIH1   A0A2U3W768   A0A3P4RWS3   I3MDQ7   A0A2K5MRH9   B5THN4   A0A2R9BA21   A0A2K6SED4   A0A2Y9KCT3   G5AVY5   A0A1A6H8W8   L8HZR9   E1B836   A0A2R8MNP1   A0A2Y9DSY3   A0A0N8JYV0  

KEGG

101746820    no KO assigned | (RefSeq) enkurin

GO

GO:0003729   GO:0005849   GO:0006378   GO:0016787   GO:0005730   GO:0030687   GO:0030163   GO:0036402   GO:0000466   GO:0005737   GO:0000463   GO:0043021   GO:0005524   GO:0000387   GO:0001669   GO:0005516   GO:0097228   GO:0003676   GO:0017124  

PANTHER

PTHR21490:SF0   PTHR13047  

Subcellular location

Nucleus  
Nucleolus  
Nucleoplasm  
  

Length:

133

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.00039

Exp number, first 60 AAs:

0

Total prob of N-in:

0.04977

outside

1  -  133

 

 

Pi

5.202077

Theta

26.316563

Tajima's D

-2.026876

CLR

0.150524

CSRT

0.0130993450327484

Interpretation

Uncertain