Gene

KWMTBOMO00059  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA002096

Annotation

PREDICTED:_protein_tyrosine_phosphatase_isoform_X2_[Bombyx_mori]

Location

Bomo_Chr1(+):1834761-1898321      View in EpiBrowser

Location in the cell

Cytoplasmic   Reliability : 2.137 Nuclear   Reliability : 2.15

CDS

ATGAATCCGAAGTTGAACAGCATTGAAGCCGAATATCTGGATATCATGCACAGGAATGGGTGGCCCCTGATTTATCAGAGGGTCGGTCAGGAGTGTCAAAAGCTCCCGTACACTTGTGTGGAGGCGAAGAGGCCTCACAACAAGGCGCTGAACCGCTACCGCGACGTGAACCCGTACGACCACAGCCGCATCGTCCTACAGCGTAGCGAGAACGATTACATAAACGCTAATCTCGTTAGGATGGAAAGCGCTGATCGCCAGTACATCCTGACTCAGGGACCGCTTGCGTTCACCGTAGGCCACTTTTGGCTGATGGTCTGGGAGCAGAACAGCCGCGCCGTCCTAATGCTGAACAAGGTCATCGAGAAAAACGAGATCAAGTGTCACTGGTACTGGCCCCATGGAAACGGCGAACAGCACAAGATGCTGCTAACAGATGTGAATCTTAGCGTCGAACAGATAAGCGAGGAGGAATGCCCAAACTACTCCATTCGGGTGCTTAAGCTATGCGATCTGGAGAGCTCCGAGAGTCGCGAGGTCATCCAGTTCCATTACACAACTTGGCCCGACTTCGGAGTGCCGTCTTCTCCTCACGCATTCCTCGAATACTTGAAGAAGATCCGCGATGCTGGCGCTTTGGAGAACGATGTTGGGCCAGCGGTCGTGCATTGCAGCGCCGGCATCGGTCGCTCTGGAACGTTCTGTCTCGTTGACTCCACTATGGTTATGATACAAAAGGCCGATGTGAAGTCTATCAACATCGAGCACATTATGCTTGAGATGCGCAAGTATCGCATGGGTCTAATTCAGACACCTGATCAGCTGCGTTTCTCGTACGAGGCCATCATCGAGGGGGCGAAGAGGGAGGACCCCAACTACGTACCTTCCAATATGGTCGAGAGCGTGTACTCGCCGGTGACTGACGTCGAAGATGATTGTCCTCCTCCGCCTCCTCCGCGCGGTGAGAGCCTCTGTCGCCCTCCTGCTCGTCCCTTGCCCGCGATTCCTTCAAGCATGTCTCTAGGCGAACTTCACCTGAGCGCTCCCGTCGAGTCTTCGAGCTCTGACGAATGTCCCCCCACTCCCCCAGAATTAGAACTACCGCCCTTCTCTTCAGCCGACGAAGATGAAGAACAGTCCGCCGTCCAGCCCGAGAGCAGCAGCGGCGCCAAGACGGAGACACTGCGCCGTCGTCGCATCCGCGAGCTGTCCGAGCGCGTCTCTCTGATGAAGCGACGGGCCCGCGACGCCGAACGATGGCACAACCTCAAGAGGTTTAAATTCGAAGAGAACAAAGAACATTGA

Protein

MNPKLNSIEAEYLDIMHRNGWPLIYQRVGQECQKLPYTCVEAKRPHNKALNRYRDVNPYDHSRIVLQRSENDYINANLVRMESADRQYILTQGPLAFTVGHFWLMVWEQNSRAVLMLNKVIEKNEIKCHWYWPHGNGEQHKMLLTDVNLSVEQISEEECPNYSIRVLKLCDLESSESREVIQFHYTTWPDFGVPSSPHAFLEYLKKIRDAGALENDVGPAVVHCSAGIGRSGTFCLVDSTMVMIQKADVKSINIEHIMLEMRKYRMGLIQTPDQLRFSYEAIIEGAKREDPNYVPSNMVESVYSPVTDVEDDCPPPPPPRGESLCRPPARPLPAIPSSMSLGELHLSAPVESSSSDECPPTPPELELPPFSSADEDEEQSAVQPESSSGAKTETLRRRRIRELSERVSLMKRRARDAERWHNLKRFKFEENKEH

Catalytic Activity

H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate

Uniprot

F2Z7K2   H9IXW3   A0A212F9N2   A0A2A4JEA4   A0A194Q4R7   A0A0M8ZR59   + More
A0A194QVS8   A0A1Y1NGH0   A0A1Y1NLC4   V9IJC8   A0A2A3EMG7   A0A026WSH5   A0A088A9T3   A0A310S4Y0   A0A154P8J7   A0A0J7KY87   E2A118   A0A232FPK1   K7IW23   A0A1L8DLQ0   A0A1L8DLM4   A0A0A1XAE1   A0A1L8DM46   A0A182G3J1   A0A1S4F057   A0A0A1WR00   A0A1Q3F3X2   A0A139WLR4   A0A158NJ25   A0A023F0Y9   A0A1S4F055   A0A1Q3F3Z9   A0A195B6L2   D6WF82   A0A069DU32   A0A0L7QWY6   A0A1B6D5J2   A0A1A9W4A5   A0A151XK75   A0A1B6CAH5   E9IUJ4   A0A0V0G9N3   A0A0K8UPX5   A0A034VKG1   A0A0K8WC51   A0A182KW25   A0A224XD80   A0A1B0AVR3   A0A0L0BPA4   A0A034VLI5   F4WCH6   W8B1A4   A0A2M4BKY4   A0A195EL52   A0A0Q9XB75   B4KZ08   A0A2M4CPT6   A0A182LRF0   A0A0Q9WI44   A0A2M4BFJ4   B4LE80   A0A2M4AFC3   A0A2M4BFM3   A0A2M4AET3   A0A2W1BNF9   A0A195C5P4   A0A182R2L5   U5EYG1   B4J260   Q7PNX1   A0A1I8MBM0   A0A1I8MBM4   A0A182YNM0   A0A1I8NLY9   A0A1I8NLY3   A0A182XD23   A0A182HMF4   A0A182TTC4   A0A182WAL7  

Pubmed

21296154    19121390    22118469    26354079    28004739    24508170    + More
20798317    28648823    20075255    25830018    26483478    17510324    18362917    19820115    21347285    25474469    26334808    21282665    25348373    20966253    26108605    21719571    24495485    17994087    28756777    12364791    25315136    25244985   

EMBL

AB543068    BAK19072.1    BABH01015741    BABH01015742    AGBW02009564    OWR50438.1    + More
NWSH01001692    PCG70407.1    KQ459463    KPJ00537.1    KQ435891    KOX69445.1    KQ461108    KPJ09070.1    GEZM01003658    JAV96648.1    GEZM01003660    GEZM01003659    JAV96647.1    JR048067    AEY60571.1    KZ288212    PBC32880.1    KK107119    EZA58596.1    KQ773232    OAD52414.1    KQ434846    KZC08245.1    LBMM01002117    KMQ95253.1    GL435638    EFN72871.1    NNAY01000002    OXU32287.1    GFDF01006743    JAV07341.1    GFDF01006742    JAV07342.1    GBXI01006597    JAD07695.1    GFDF01006647    JAV07437.1    JXUM01040880    JXUM01040881    JXUM01040882    JXUM01040883    JXUM01040884    JXUM01040885    KQ561263    KXJ79163.1    GBXI01013464    GBXI01009827    JAD00828.1    JAD04465.1    GFDL01012808    JAV22237.1    KQ971319    KYB28833.1    ADTU01001874    ADTU01001875    ADTU01001876    ADTU01001877    GBBI01003535    JAC15177.1    GFDL01012782    JAV22263.1    KQ976582    KYM79824.1    EFA00470.2    GBGD01001613    JAC87276.1    KQ414705    KOC63138.1    GEDC01016346    JAS20952.1    KQ982052    KYQ60705.1    GEDC01026806    GEDC01009209    JAS10492.1    JAS28089.1    GL765979    EFZ15760.1    GECL01001406    JAP04718.1    GDHF01023904    JAI28410.1    GAKP01015975    GAKP01015973    GAKP01015972    GAKP01015971    GAKP01015969    JAC42979.1    GDHF01003889    JAI48425.1    GFTR01006031    JAW10395.1    JXJN01004378    JRES01001668    KNC21059.1    GAKP01015976    GAKP01015974    GAKP01015970    GAKP01015968    JAC42982.1    GL888070    EGI68156.1    GAMC01019519    JAB87036.1    GGFJ01004574    MBW53715.1    KQ978739    KYN28856.1    CH933809    KRG05776.1    EDW17805.1    GGFL01003111    MBW67289.1    AXCM01000178    CH940647    KRF84147.1    GGFJ01002685    MBW51826.1    EDW69036.1    GGFK01006170    MBW39491.1    GGFJ01002686    MBW51827.1    GGFK01005911    MBW39232.1    KZ149952    PZC76589.1    KQ978292    KYM95493.1    GANO01000323    JAB59548.1    CH916366    EDV97011.1    AAAB01008960    EAA11394.4    APCN01004428   

Proteomes

UP000005204    UP000007151    UP000218220    UP000053268    UP000053105    UP000053240    + More
UP000242457    UP000053097    UP000005203    UP000076502    UP000036403    UP000000311    UP000215335    UP000002358    UP000069940    UP000249989    UP000007266    UP000005205    UP000078540    UP000053825    UP000091820    UP000075809    UP000075882    UP000092460    UP000037069    UP000007755    UP000078492    UP000009192    UP000075883    UP000008792    UP000078542    UP000075900    UP000001070    UP000007062    UP000095301    UP000076408    UP000095300    UP000076407    UP000075840    UP000075902    UP000075920   

PRIDE

F2Z7K2    H9IXW3   

Pfam

PF00102   Y_phosphatase

Interpro

IPR016130   Tyr_Pase_AS        + More
IPR029021   Prot-tyrosine_phosphatase-like       
IPR003595   Tyr_Pase_cat       
IPR012265   Ptpn1/Ptpn2       
IPR000242   PTPase_domain       
IPR000387   TYR_PHOSPHATASE_dom       

SUPFAM

SSF52799   SSF52799       

Gene 3D

3.90.190.10    

ProteinModelPortal

F2Z7K2   H9IXW3   A0A212F9N2   A0A2A4JEA4   A0A194Q4R7   A0A0M8ZR59   + More
A0A194QVS8   A0A1Y1NGH0   A0A1Y1NLC4   V9IJC8   A0A2A3EMG7   A0A026WSH5   A0A088A9T3   A0A310S4Y0   A0A154P8J7   A0A0J7KY87   E2A118   A0A232FPK1   K7IW23   A0A1L8DLQ0   A0A1L8DLM4   A0A0A1XAE1   A0A1L8DM46   A0A182G3J1   A0A1S4F057   A0A0A1WR00   A0A1Q3F3X2   A0A139WLR4   A0A158NJ25   A0A023F0Y9   A0A1S4F055   A0A1Q3F3Z9   A0A195B6L2   D6WF82   A0A069DU32   A0A0L7QWY6   A0A1B6D5J2   A0A1A9W4A5   A0A151XK75   A0A1B6CAH5   E9IUJ4   A0A0V0G9N3   A0A0K8UPX5   A0A034VKG1   A0A0K8WC51   A0A182KW25   A0A224XD80   A0A1B0AVR3   A0A0L0BPA4   A0A034VLI5   F4WCH6   W8B1A4   A0A2M4BKY4   A0A195EL52   A0A0Q9XB75   B4KZ08   A0A2M4CPT6   A0A182LRF0   A0A0Q9WI44   A0A2M4BFJ4   B4LE80   A0A2M4AFC3   A0A2M4BFM3   A0A2M4AET3   A0A2W1BNF9   A0A195C5P4   A0A182R2L5   U5EYG1   B4J260   Q7PNX1   A0A1I8MBM0   A0A1I8MBM4   A0A182YNM0   A0A1I8NLY9   A0A1I8NLY3   A0A182XD23   A0A182HMF4   A0A182TTC4   A0A182WAL7  

PDB

5KA1     E-value=2.8687e-88,     Score=830

KEGG

100579140    K05696 tyrosine-protein phosphatase non-receptor type 1 [EC:3.1.3.48] | (RefSeq) Bmptp-Z; protein ty

GO

GO:0004725   GO:0016021   GO:0016311   GO:0016791   GO:0006470   GO:0005524   GO:0048013   GO:0005003   GO:0005887   GO:0007169  

Length:

434

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

2.07838

Exp number, first 60 AAs:

0

Total prob of N-in:

0.10570

outside

1  -  434

 

 

Pi

22.308631

Theta

22.369441

Tajima's D

-1.160059

CLR

0.035354

CSRT

0.108594570271486

Interpretation

Uncertain