Gene

KWMTBOMO00058

Annotation

reverse_transcriptase_[Bombyx_mori]

Location

Bomo_Chr1(+):1816511-1821021      View in EpiBrowser

Full name

Probable RNA-directed DNA polymerase from transposon BS      

Alternative Name

Reverse transcriptase

Location in the cell

Mitochondrial   Reliability : 1.404 Nuclear   Reliability : 1.972

CDS

ATGGACGCTGTATTCGCGGAATTCCTCCGACTTCGCCACCCACAGCTCGCCTCGGAGTTTTTGGCCTTCAAGGCCAATCACACTGCGAGCCCTCTCGAGGACTCCGCCGCGCTCGCTGCTCCTGCGTCGCCTGTACCTGCGTGCAGAGCTTCTGCATTGAGCACCGCAGCCTCTGTCGTGCCTGCCGCTCCCGTGTCGCCTATACTGGCGAGAAAAGCTGCTGCGTCGTCCGCCGTGACCATCGTTTCAGCTGAGCGATCATCCGCGGCCTCCGTCGCGCCCTCTAAAACACCTACACTTGCTCGTAGGTCGCCTGCACCCGCCTCCTCGTGCTCCGACTCTGACTCGGACATGGAGGTCGACCTCGCCCCCGCCTCATCGACGGATGGATTCACCCTGGTACAGAAGGGTAAGAAGCGTGCCGCGGAGTCTCGAGCTCCCGCGGCCGCTAAAATTAGCAAAGCCGTGAACGCGTCGCGCCCCCGCCCTCAGACTCCCGTTGCGCCCCCAGCCCGTGCCACTCCGTCGCCGCGTCCGGTGGCACAAAATAAAACCCAGACCCCTCCCCCGGTTATCCTTCAGGAGAAGGCAGCTTGGGATCGAGTTTGCCTGGCCCTTAAGGCCAAAAATATAAATTTCACGAATGCCCGTAACCTCGCGAACGGCATTCAAATTAAGGTTCAAACACCCGACGACCATAGGGCCCTCTCTTCTTACCTCCGTAAGGAGCGTATAAGTTTCCATACGTATACGCTCCAGGAGGAGCGCGAACTCCGCGTTGTAATACGCGGAATCCCTAAAGAGTTAGATGTAGAGCTCGTAAAAGCCGACCTGTTAGAACAAGGCCTACCAGTGAATTCTGTGCACCGTATGCACACCGGTCGCGGTAGGGAGCCATATAATATGGTTCTAGTCGCTCTCCAGCCTACCCCGAGGGAGACCCTACTTAAGCCCGCGCGCCGTGACCCTAAAATCGCGAACTATAACATGGTCAGGAACGACAGGCTCTCTGCCCGTGGTGGTGGTACCGTCATTTACTATAGAAGAGCCCTGCATTGCGTCCCGCTCGATCCTCCCGCGCTCGCTAATATCGAAGCATCAGTGTGCCGAATCTCACTGACGGGACACGCGCCGATCGTTATCGCGTCCGTTTATCTTCCACCGGATAAGATCGTTCTAAGCAGTGATATCGAGGCGCTGCTCGGTATGGGGAGCTCTGTCATTCTGGCGGGCGACCTAAATTGTAAACACATCAGGTGGAACTCACACACCACAACCCCGAATGGCAGGCGGCTTGACGCGTTAGTCGATGATCTCGCCTTCGATATCGTCGCTCCGCTAACCCCGACTCACTACCCGCTAAATATCGCGCATCGCCCGGATATACTCGACATAGCGTTATTAAAAAACGTAACTCTGCGCTTACACTCGATCGAAGTAGTTTCAGAGTTAGATTCAGACCACCGTCCCGTCGTTATGAAGCTCGGTCGCGCTCCCGATTCCGTTCCCGTCACGAGGACTGTGGTGGATTGGCACACGCTGGCCATCAGCCTGGCTGAATCTGATCCACCATCGCTCCCGTTTAACCCGGACTCTATCCCGTCTCCTCAGGATACCGCTGAAGCCATAGACATCTTAACGTCACACATCACCTCGACATTAGATAGGTCATCGAAACAAGTTGTAGCGGAGGACTTCCTTCACCGCTTCAAATTGTCCGACGATATTAGGGAACTCCTTAGAGCTAAGAACGCCTCGATACGCGCCTACGACAGGTATCCTACCGCGGAAAATCGTATTCGAATGCGTGCCCTACAACGCGACGTAAAGTCTCGCATCGCCGAAGTCCGAGATGCCAGATGGTCTGATTTCTTAGAAGGACTCGCGCCCTCCCAAAGGTCTTACTACCGCTTAGCTCGCCGACTCGCGGCGTTCGATGATGACGAAAAAGCAGAGCTGCTGGCCGATACATTGCAAACCCAGTGCACGCCCAGCACTCAATCCGTGGACCCTGTTCATGTAGAATTAGTAGACAGTGAGGTAGAACGCAGAGCCTCCTTGCCACCCTCTGATGCGTTACCACCCGTCACCCCGATGGAAGTTAAAGACTTGATCAAAGACCTACGTCCTCGCAAGGCTCCCGGTTCCGACGGTATATCCAACCGCGTTATTAAACTTCTACCCGTCCAACTCATCGTGATGTTGGCATCTATTTTCAATGCCGCTATGGCGAACTGTATCTTTCCCGCGGTGTGGAAAGAAGCGGACGTTATCGGCATACATAAACCCGGTAAACCAAAAAATCATCCGACGAGTTACCGCCCGATTAGCCTCCTCATGTCTCTAGGCAAACTGTATGAGCGTCTGCTCTACAAACGCCTCAGAGACTTCGTCTCATCCAAGGGCATTCTTATCGATGAACAATTCGGATTCCGTACAAATCACTCATGCGTTCAACAGGTGCACCGCCTCACGGAGCACATTCTTGTGGGGCTTAATCGACCAAAACCGTTATACACGGGAGCTCTCTTCTTCGACGTCGCAAAAGCGTTCGACAAAGTCTGGCACAATGGTTTGATTTTCAAACTATTCAACATGGGCGTGCCGGATAGTCTCGTGCTCATCATACGGGACTTCTTGTCGAACCGCTCTTTTCGATATCGAGTCGAGGGAACCCGCTCCTCCCGACGACCTCTCACAGCTGGAGTCCCGCAAGGCTCTATCCTCTCACCCCTCCTATTTAGCTTATTCGTCAACGATATTCCCCGGTCGCCGCCGACCCATTTAGCTTTATTCGCCGACGACACGACTGTTTACTATTCTAGTAGAAATAAGTCCCTAATCGCGAAGAAGCTTCAGAGCGCAGCCCTAGCCCTAGGACAGTGGTTCCGAAAATGGCGCATAGACATCAACCCAGCGAAAAGTACTGCGGTGCTATTTCAGAGGGGAAGCTCCACACGGATTTCCTCCCGGATTAGGAGGAGGAATCTCACACCCCCGATTACTCTCTTTAGACAACCCATACCCTGGGCCAGGAAGGTCAAGTACCTGGGCGTTACCCTGGATGCATCGATGACATTCCGCCCGCATATAAAATCAGTCCGTGACCGTGCCGCGTTTATTCTCGGTAGACTCTACCCCATGATCTGTAAGCGGAGTAAAATGTCCCTTCGGAACAAGGTGACACTTTACAAAACTTGCATAAGGCCCGTCATGACTTACGCGAGTGTGGTGTTCGCTCACGCGGCCCGCACACACATAGACACCCTCCAATCCCTACAATCCCGCTTTTGCAGGAGCCAGTCACCGTCGACGCCCTAG

Protein

MDAVFAEFLRLRHPQLASEFLAFKANHTASPLEDSAALAAPASPVPACRASALSTAASVVPAAPVSPILARKAAASSAVTIVSAERSSAASVAPSKTPTLARRSPAPASSCSDSDSDMEVDLAPASSTDGFTLVQKGKKRAAESRAPAAAKISKAVNASRPRPQTPVAPPARATPSPRPVAQNKTQTPPPVILQEKAAWDRVCLALKAKNINFTNARNLANGIQIKVQTPDDHRALSSYLRKERISFHTYTLQEERELRVVIRGIPKELDVELVKADLLEQGLPVNSVHRMHTGRGREPYNMVLVALQPTPRETLLKPARRDPKIANYNMVRNDRLSARGGGTVIYYRRALHCVPLDPPALANIEASVCRISLTGHAPIVIASVYLPPDKIVLSSDIEALLGMGSSVILAGDLNCKHIRWNSHTTTPNGRRLDALVDDLAFDIVAPLTPTHYPLNIAHRPDILDIALLKNVTLRLHSIEVVSELDSDHRPVVMKLGRAPDSVPVTRTVVDWHTLAISLAESDPPSLPFNPDSIPSPQDTAEAIDILTSHITSTLDRSSKQVVAEDFLHRFKLSDDIRELLRAKNASIRAYDRYPTAENRIRMRALQRDVKSRIAEVRDARWSDFLEGLAPSQRSYYRLARRLAAFDDDEKAELLADTLQTQCTPSTQSVDPVHVELVDSEVERRASLPPSDALPPVTPMEVKDLIKDLRPRKAPGSDGISNRVIKLLPVQLIVMLASIFNAAMANCIFPAVWKEADVIGIHKPGKPKNHPTSYRPISLLMSLGKLYERLLYKRLRDFVSSKGILIDEQFGFRTNHSCVQQVHRLTEHILVGLNRPKPLYTGALFFDVAKAFDKVWHNGLIFKLFNMGVPDSLVLIIRDFLSNRSFRYRVEGTRSSRRPLTAGVPQGSILSPLLFSLFVNDIPRSPPTHLALFADDTTVYYSSRNKSLIAKKLQSAALALGQWFRKWRIDINPAKSTAVLFQRGSSTRISSRIRRRNLTPPITLFRQPIPWARKVKYLGVTLDASMTFRPHIKSVRDRAAFILGRLYPMICKRSKMSLRNKVTLYKTCIRPVMTYASVVFAHAARTHIDTLQSLQSRFCRSQSPSTP

Catalytic Activity

a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1)

Cofactor

Mg(2+)
Mn(2+)

Keywords

Nucleotidyltransferase   RNA-directed DNA polymerase   Transferase   Transposable element  

Feature

chain  Probable RNA-directed DNA polymerase from transposon BS

Uniprot

Q93137   Q9BPQ0   Q9XXW0   A0A0N1PFV1   O96546   A0A1Y1NA23   + More
A0A139W8G9   V5GNJ2   A0A139WA11   X1WLB2   V5GNF3   A0A023EYS8   A0A2S2PPK8   A0A2J7PU96   X1WNI2   A0A087UCW3   A0A2J7QY69   A0A2J7QR37   A0A2J7PBY3   A0A023EZE6   K7IN67   A0A2J7Q6J2   A0A2S2QEE0   A0A224X6Q4   X1WZH0   A0A2J7R7D0   J9LFC9   J9M522   A0A224XB44   A0A224X6T4   A0A2S2Q383   A0A2J7RE85   A0A2M4CV52   A0A224XI99   A0A224X6S1   A0A2M4BDV6   A0A2M4BD67   A0A2M4CV42   A0A224XJI0   Q07995   A0A3N5Z7I3   J9KLB1   A0A224X746   A0A224X6W2   A0A2S2NH02   A0A2S2N814   A0A224X6U5   A0A0V0G5B6   A0A087UGF5   A0A2M4BD66   A0A2M4BDA5   A0A2M4BD62   A0A2M4BD83   A0A224XIB0   A0A0A9YJ00   A0A0A9YU04   A0A2J7QB68   A0A023F069   A0A2S2N6Q7   A0A069DZL8   Q95SX7   A0A2H8TF37   Q8T9X4   A0A1Y1KFR3   Q8I7P8   A0A2J7PDM0   A0A1Q3G5J4   A0A069DX78   A0A2S2P7B2   A0A224X6R6   A0A2J7PVX3   A0A224X724  

EC Number

2.7.7.49

Pubmed

10333566    26354079    10380107    28004739    18362917    19820115    + More
25474469    20075255    8387152    30086797    25401762    26334808    7753626    12537569   

EMBL

U07847    AAA17752.1    AB055391    BAB21761.1    AB018558    BAA76304.1    + More
KQ459265    KPJ02064.1    AF081103    AAC72921.1    GEZM01008457    JAV94772.1    KQ973342    KXZ75569.1    GALX01005299    JAB63167.1    KQ971729    KYB24751.1    ABLF02042518    ABLF02057746    GALX01005359    JAB63107.1    GBBI01004395    JAC14317.1    GGMR01018716    MBY31335.1    NEVH01021205    PNF19912.1    ABLF02008153    ABLF02008462    ABLF02008464    KK119261    KFM75202.1    NEVH01009134    PNF33528.1    NEVH01011985    PNF31054.1    NEVH01027074    PNF13841.1    GBBI01004571    JAC14141.1    NEVH01017470    PNF24199.1    GGMS01006359    MBY75562.1    GFTR01008279    JAW08147.1    ABLF02034467    NEVH01006736    PNF36716.1    ABLF02023911    ABLF02024246    GFTR01008262    JAW08164.1    GFTR01008261    JAW08165.1    GGMS01002992    MBY72195.1    NEVH01005277    PNF39135.1    GGFL01004957    MBW69135.1    GFTR01008256    JAW08170.1    GFTR01008271    JAW08155.1    GGFJ01001857    MBW50998.1    GGFJ01001858    MBW50999.1    GGFL01005012    MBW69190.1    GFTR01008257    JAW08169.1    S59870    AAB26437.2    RPOV01000134    RPJ78669.1    ABLF02040174    ABLF02040183    ABLF02055266    GFTR01008151    JAW08275.1    GFTR01008260    JAW08166.1    GGMR01003864    MBY16483.1    GGMR01000676    MBY13295.1    GFTR01008251    JAW08175.1    GECL01003538    JAP02586.1    KK119692    KFM76444.1    GGFJ01001844    MBW50985.1    GGFJ01001842    MBW50983.1    GGFJ01001843    MBW50984.1    GGFJ01001822    MBW50963.1    GFTR01008246    JAW08180.1    GBHO01010547    GBHO01010546    JAG33057.1    JAG33058.1    GBHO01021814    GBHO01010549    JAG21790.1    JAG33055.1    NEVH01016302    PNF25823.1    GBBI01003810    JAC14902.1    GGMR01000226    MBY12845.1    GBGD01000415    JAC88474.1    AY060438    AAL25477.1    GFXV01000908    MBW12713.1    AF456125    AAL57609.1    GEZM01084969    JAV60363.1    AY180919    AAN87272.1    NEVH01026386    PNF14434.1    GFDL01000006    JAV35039.1    GBGD01000389    JAC88500.1    GGMR01012676    MBY25295.1    GFTR01008269    JAW08157.1    NEVH01020940    PNF20481.1    GFTR01008169    JAW08257.1   

Proteomes

UP000053268    UP000007266    UP000007819    UP000235965    UP000054359    UP000002358    + More

PRIDE

Q93137    Q9BPQ0    Q9XXW0    Q95SX7    Q8T9X4    Q8I7P8    + More

Pfam

PF00078   RVT_1        + More
PF14529   Exo_endo_phos_2
PF07530   PRE_C2HC
PF03372   Exo_endo_phos
PF07727   RVT_2

Interpro

IPR036691   Endo/exonu/phosph_ase_sf        + More
IPR005135   Endo/exonuclease/phosphatase       
IPR000477   RT_dom       
IPR006579   Pre_C2HC_dom       
IPR013103   RVT_2       

SUPFAM

SSF56219   SSF56219       

Gene 3D

3.60.10.10    

ProteinModelPortal

Q93137   Q9BPQ0   Q9XXW0   A0A0N1PFV1   O96546   A0A1Y1NA23   + More
A0A139W8G9   V5GNJ2   A0A139WA11   X1WLB2   V5GNF3   A0A023EYS8   A0A2S2PPK8   A0A2J7PU96   X1WNI2   A0A087UCW3   A0A2J7QY69   A0A2J7QR37   A0A2J7PBY3   A0A023EZE6   K7IN67   A0A2J7Q6J2   A0A2S2QEE0   A0A224X6Q4   X1WZH0   A0A2J7R7D0   J9LFC9   J9M522   A0A224XB44   A0A224X6T4   A0A2S2Q383   A0A2J7RE85   A0A2M4CV52   A0A224XI99   A0A224X6S1   A0A2M4BDV6   A0A2M4BD67   A0A2M4CV42   A0A224XJI0   Q07995   A0A3N5Z7I3   J9KLB1   A0A224X746   A0A224X6W2   A0A2S2NH02   A0A2S2N814   A0A224X6U5   A0A0V0G5B6   A0A087UGF5   A0A2M4BD66   A0A2M4BDA5   A0A2M4BD62   A0A2M4BD83   A0A224XIB0   A0A0A9YJ00   A0A0A9YU04   A0A2J7QB68   A0A023F069   A0A2S2N6Q7   A0A069DZL8   Q95SX7   A0A2H8TF37   Q8T9X4   A0A1Y1KFR3   Q8I7P8   A0A2J7PDM0   A0A1Q3G5J4   A0A069DX78   A0A2S2P7B2   A0A224X6R6   A0A2J7PVX3   A0A224X724  

PDB

6AR3     E-value=0.0905943,     Score=88

KEGG

105841788    no KO assigned | (RefSeq) predicted GPI-anchored protein 58

GO

GO:0003964   GO:0004519   GO:0006313  

Length:

1106

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

2.81062000000001

Exp number, first 60 AAs:

0.00071

Total prob of N-in:

0.00013

outside

1  -  1106

 

 

Pi

0

Theta

0

Tajima's D

0

CLR

2.125048

CSRT

0

Interpretation

Uncertain