Gene

KWMTBOMO00003  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA002074

Annotation

PREDICTED:_anion_exchange_protein_3_isoform_X2_[Bombyx_mori]

Location

Bomo_Chr1(+):51976-71352      View in EpiBrowser

Full name

Anion exchange protein      

Location in the cell

PlasmaMembrane   Reliability : 3.899

CDS

ATGAGCTCCGGGAAAAGAAAACTCTCGTTCCTCGGCTTCGCTCCGCAGCAGGCCGCAGGCGATGACGAGGTGCAACTGGACGAGGAGATGGACCGCGTGGTGTGGGGCGAGGGGCAGGGTCCACCGCCCAGCGACGCCACGCCGCGCAGGGATCTCGCCGCCCCGCCACCCTACGCAACAGATGCAGATACTTCCCGGACTGGACCCGAGCAACTCGAACCTGCGACGGATCCCCACCTGAATCAGACGACGTCAGCGGCGGAGGAGCGACGCGTGCAGTTCGACGGAGGGAGCCCGGCGCCGCGCGCCGACGCCCCGGCCGTCGCGCTTGCGGACGCCGACCGACGCGCTGAGAGGAATGCACGACACGGACACAAGTCGCGGAAGTACTCGTTGCAAGAGGGCGGGGAGCGAACTGCTTCTGACGATGAAGGCCTTGAAGAATCGCAGAGAGACCAGCTTAGTCACCGCACCGATGACCCGCGCGCTCTTCGTCGTCACAAGATACAACCCAAGACATCAACGGTCCACGTCGGTCGTAAGGATGGCGGTGACAAGGTCCAGAACATTCTTCCTGATGCGACATATAAGAAAATGTACGACCACAGTCCGCACGCGGTGTTCGTGCAACTGGACGAGCTGCTGGCGACGGAGGACGGCGAAGCGGAGTGGAAGGAGACGGCGCGCTGGATCAAGTACGAGGAGGACGTGGAGGAGGGCTCGGCGCGCTGGGGGCGGCCCCACGTCGCGTCGCTCTCATTCCACTCGCTGCTGAACCTGCGCCGCTGTCTAGAGACCGGCGTCGTGCTGCTAGACCTTGACGAGAAGGACTTGCCCGGCGTCGCCTACAGGGTCGTGGAGAGTATGGTGACGGAAGGCCTGATCGAGGAGGACGACAAGCCCGTCGTGATGCGTTCGTTGCTGTTGCGGCACCGGCATGTCCACGACGACCGCGGGTTTCGCTTTTCCATCAGCAGCAAGAAGCCCGCATCCTACAGCAGTCTGCAGAATCTATCGGAGCGTCGGCGGCGCAGCACGCACGCGCGGCCCTCGGCGGCCGGGCTGGACCCGCGCGAGGTCGAGTACCTGGCGCACGCTTCCGAGTCGCAGGATGAGCTGCGCCGCACTCACAACGACTCGATCCTGAAGCGCATCCCGGACGACGCCGAGGCCACCACTGTACTGGTCGGCGCCGTCGGCTTCCTGGACCAGCCGACCATCGCCTTCGTGCGTCTCGCCGAGGGAATATACATGCCTTCGATAACCGAGGTGCCCGTCCCGGTCCGATTCATGTTCATTCTGTTGGGACCCGGTGGAGCTGATCTCGACTACCATGAGGTCGGTCGGTCTATCTCGACGCTCATGTCGAACCCTGCGTTCCACTCGATCGCGTACAAGGCGGACGACCGTCGGGAGCTTCTCTCGGCTATCAACGAATTTCTCGACGACTCCATAGTGTTGCCGCCCGGAGACTGGGAGCGCCAAGCGCTGCTGCCGCTCGAGGAGCTGCGCGCTAAGAGTGAAATGATCCGGCGTCGCAAAATAAACGCCTTAGAGCGCAAGCGCATCGTCGCGGACGGGGACAAGCCTTCAGACGAAAAGAAAGCGTTGCTCGCGGCCGAGGCAGGAGGGATGCCTCCCGAAGAACCCGACGATCCTCTCTCTAGAACGGGACGACTGTTTGGAGGTGTGATCCGGGACATGAAGAGGCGGTACCCCTTCTACGTGTCCGACTTTGTTGACGCGCTAAATGGTCAATGCGTCGCGGCCACCATCTTCATGTACTTCGCAGCGGTTTCCTCTGCTATTACTTTCGGGGGACTGTTGGCAGAGAAGACATACGGCAAAATTGGTATCTCCGAAACTCTGGTGTTCACGAGCGCTGGCGGCGTGCTGTTCGCGCTGGTGGCCGGCCAGCCTATGATGATAACCGGAGCGACGGGGCCGCTGCTGCTGCTCGACGAGTCGCTGGCCAACTTCTGTCACTCGTACGGGTTCGACTTCCTCGCGGCGCGCATGTACTGCGGCCTCTGGATGATAGTGATCGCGCTATGCGTCGCTTCCGTCGAGGGCAGCGTCGCAGTTAAAAAGATTACCAGGTTCACTGAGGATATCTTCGCTTTCCTGATATCGTTGATCTTCATATCGGAACCCATCACGAGCACCATCGCCGTGTACCGCGCCAACCCGCTCGGTATCGACTACTGCCAGTTCCGAGAGGTGGCCCTCTCGAATTCCACAGTGCAGCCGCTTCTAAACTCTACTTCAGTCGGTAACTCTAGCGTGGTCGCCCCAGCGCCGCCCGTCTCCAGACTGCCTCCGCAGCCCAACACGGCTCTCTTCTGCACCATGCTGACGCTGGCCACCTTCGTCTTGGCGTACTACCTCAGAATTTTTCGCAACGGCAAGTTCCTCGGTCGCAGCGCTCGTCGAGCGCTGGGTGATTTCGGAGTGCCGATCGCGATCGTGCTGATGGTCGGCATCTCTTGCTTGGTGCCGGTGAAGACAGAGACCCTGGTGGTGCCGGCTGGTCTCAACCCCACTACTGTGCGCAGTTGGTTCGTGCCGCTCAATCCTGGACTGGAGACCATCCCGGCTTGGGCAGCTTTTGCTATGGCGCTGCCGGCGCTCATGGTTTACATCATCGTCTTCATGGAAACGCACATCGCCGAGTTGATCATCGCGAAGCCGGAACGGAGGCTGAAGAAGGGTAGCGGGTTTCACATGGACATCGTGATAATGTCGTTTGTGAACGCGCTGTGCGGCATGTTCGGCGCGCCGTGGCAGTGCGTGGCCACGGTGCGGTCCGTGAGCCACGTGTCGGCGCTCACCATCATGTCTACGACGCACGCGCCGGGGGACAAGCCGCACATCGTGGAGGTGAAGGAGCAGCGGCTGACGGGCCTGCTCGTGGCGGTGATGGTCGGCATCTCGGTGCTCGCTTCGGGCTGGCTCTGTCTCGTGCCCATGGCGGTGCTCTTCGGCGTTTTCCTCTACATGGGGATCTCTGCGCTCGGCGGAATACAGTTCTGGGACCGTTGTATTCTACTTCTCAAGCCAGTCAAACACCACCCGCAACTTCCTTACGTTAGACGGGTGCCGACTCTGAAGATGCACATGTACACGCTGATCCAAGTGGGCGGCGTGGTGGTGCTGTACGCGGTGAAGTCGTCGCGGTTCTCGCTGGCGCTGCCCTTCTTCCTGGTGCTGATGGTGCCGCTGCGCATGTCGCTCGTCTACATCTTCACGCCGCTGCAGCTGCGCGCGTTGGACGGCGCCCAGAAAGATATAGACAAGGACGACGAGCCGGACTTCTACGAGGAAGCGCCGATACCGGGCTAG

Protein

MSSGKRKLSFLGFAPQQAAGDDEVQLDEEMDRVVWGEGQGPPPSDATPRRDLAAPPPYATDADTSRTGPEQLEPATDPHLNQTTSAAEERRVQFDGGSPAPRADAPAVALADADRRAERNARHGHKSRKYSLQEGGERTASDDEGLEESQRDQLSHRTDDPRALRRHKIQPKTSTVHVGRKDGGDKVQNILPDATYKKMYDHSPHAVFVQLDELLATEDGEAEWKETARWIKYEEDVEEGSARWGRPHVASLSFHSLLNLRRCLETGVVLLDLDEKDLPGVAYRVVESMVTEGLIEEDDKPVVMRSLLLRHRHVHDDRGFRFSISSKKPASYSSLQNLSERRRRSTHARPSAAGLDPREVEYLAHASESQDELRRTHNDSILKRIPDDAEATTVLVGAVGFLDQPTIAFVRLAEGIYMPSITEVPVPVRFMFILLGPGGADLDYHEVGRSISTLMSNPAFHSIAYKADDRRELLSAINEFLDDSIVLPPGDWERQALLPLEELRAKSEMIRRRKINALERKRIVADGDKPSDEKKALLAAEAGGMPPEEPDDPLSRTGRLFGGVIRDMKRRYPFYVSDFVDALNGQCVAATIFMYFAAVSSAITFGGLLAEKTYGKIGISETLVFTSAGGVLFALVAGQPMMITGATGPLLLLDESLANFCHSYGFDFLAARMYCGLWMIVIALCVASVEGSVAVKKITRFTEDIFAFLISLIFISEPITSTIAVYRANPLGIDYCQFREVALSNSTVQPLLNSTSVGNSSVVAPAPPVSRLPPQPNTALFCTMLTLATFVLAYYLRIFRNGKFLGRSARRALGDFGVPIAIVLMVGISCLVPVKTETLVVPAGLNPTTVRSWFVPLNPGLETIPAWAAFAMALPALMVYIIVFMETHIAELIIAKPERRLKKGSGFHMDIVIMSFVNALCGMFGAPWQCVATVRSVSHVSALTIMSTTHAPGDKPHIVEVKEQRLTGLLVAVMVGISVLASGWLCLVPMAVLFGVFLYMGISALGGIQFWDRCILLLKPVKHHPQLPYVRRVPTLKMHMYTLIQVGGVVVLYAVKSSRFSLALPFFLVLMVPLRMSLVYIFTPLQLRALDGAQKDIDKDDEPDFYEEAPIPG

Similarity

Belongs to the anion exchanger (TC 2.A.31) family.

Feature

chain  Anion exchange protein

Uniprot

A0A2H1VVQ0   A0A2W1B1V1   A0A212EXJ6   H9IXU1   A0A194QL83   A0A2A4JK01   + More
A0A194PFC3   U5ESC0   A0A182GLN1   D4HM38   A0A2M4B9U9   A0A2M4B9V3   A0A2M4B9X8   A0A1Q3G5A2   A0A1Q3G568   Q17LT4   A0A2M4A0B9   A0A2M4A0I7   A0A2M4A0D6   A0A2M4CSP5   A0A2M3ZFN9   A0A2M3YY57   A0A182QDR8   A0A2M4CSK8   A0A182JC93   A0A1S4GRB6   A7UU18   A0A084WRM6   A0A2A3EHC5   A0A0M9A6U3   E2C057   E2AI20   A0A0J7L1F8   A0A154P8N0   A0A195BY69   E9IUS6   A0A336KLM7   A0A1Y1MZV6   A0A158NL67   E0W1T8   A0A0R3P866   Q8IQD6   A0A034VY23   A0A232F6S7   A0A026WYT9   A0A3B0K2B8   Q6NL70   A0A0J9RTY1   A0A0Q5U3S8   A0A0A1X8C7   A0A336KIP2   A0A151WHE6   A0A0Q9WIK9   A0A0R3P8P7   A0A3L8D7S5   A0A0K8WBJ0   A0A1W4U954   A0A0R1DWP5   M9PEQ4   A0A0M4EAF3   A0A0J9RSF3   A0A0R3P500   A0A195BH70   A0A0Q9XBQ8   A0A0Q9WUH0   A0A0Q5U4F4   A0A1W4U9Q8   A0A336M5M2   A0A0R1E201   A0A0P8XT17   A0A336KG24   A0A034VVH9   Q7KUD6   Q8IQD4   A0A0J9RSY0   A0A0Q9XBW9   A0A0R1DWV7   A0A0Q5UIN4   A0A0P8Y8V0   A0A1W4UL13   A0A0L0CPJ9   A0A1W4UL47   T1PHE0   Q9VT48   B3NGL6   A0A0J9RSL2   A0A1I8PAF1   B4HLA7   A0A1W4XTB6   B4PDW1   A0A0Q5UII5   A0A0J9RTX7   A0A1B0FJB2   A0A1A9YNN6   A0A0R1DX16   A0A0J9UID3   Q7KUD7   Q8IQD5   A0A0J9RSF9   A0A1A9Z321  

Pubmed

28756777    22118469    19121390    26354079    26483478    20042685    + More
17510324    12364791    24438588    20798317    21282665    28004739    21347285    20566863    15632085    17994087    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    26109357    26109356    25348373    28648823    24508170    22936249    25830018    30249741    17550304    26108605   

EMBL

ODYU01004713    SOQ44888.1    KZ150444    PZC70852.1    AGBW02011730    OWR46219.1    + More
BABH01015588    BABH01015589    KQ461196    KPJ06318.1    NWSH01001166    PCG72291.1    KQ459605    KPI91982.1    GANO01003317    JAB56554.1    JXUM01072366    JXUM01072367    JXUM01072368    JXUM01072369    JXUM01072370    JXUM01072371    JXUM01072372    JXUM01072373    EU700988    ACH67478.1    GGFJ01000693    MBW49834.1    GGFJ01000694    MBW49835.1    GGFJ01000695    MBW49836.1    GFDL01000096    JAV34949.1    GFDL01000094    JAV34951.1    CH477213    EAT47616.1    GGFK01000945    MBW34266.1    GGFK01000948    MBW34269.1    GGFK01000946    MBW34267.1    GGFL01004121    MBW68299.1    GGFM01006489    MBW27240.1    GGFM01000461    MBW21212.1    AXCN02000966    GGFL01003983    MBW68161.1    AAAB01008960    EDO63795.1    ATLV01026173    KE525407    KFB52870.1    KZ288255    PBC30692.1    KQ435724    KOX78417.1    GL451750    EFN78667.1    GL439621    EFN66928.1    LBMM01001436    KMQ96324.1    KQ434846    KZC08275.1    KQ978501    KYM93537.1    GL766032    EFZ15680.1    UFQS01000421    UFQT01000421    SSX03813.1    SSX24178.1    GEZM01017423    GEZM01017422    JAV90698.1    ADTU01019270    ADTU01019271    ADTU01019272    ADTU01019273    DS235873    EEB19670.1    CH379069    KRT08197.1    AE014296    BT011364    AAN11926.1    AAR96156.1    GAKP01012504    GAKP01012500    JAC46448.1    NNAY01000781    OXU26541.1    KK107078    EZA60309.1    OUUW01000012    SPP87463.1    BT012471    AAS93742.1    CM002912    KMY98759.1    CH954178    KQS43736.1    GBXI01006728    GBXI01001714    JAD07564.1    JAD12578.1    SSX03812.1    SSX24177.1    KQ983120    KYQ47250.1    CH940647    KRF84378.1    KRT08192.1    QOIP01000011    RLU16537.1    GDHF01004104    JAI48210.1    CM000159    KRK01558.1    AGB94348.1    CP012525    ALC44228.1    KMY98756.1    KRT08190.1    KQ976488    KYM83499.1    CH933809    KRG05963.1    KRF84379.1    KQS43739.1    SSX03814.1    SSX24179.1    KRK01562.1    CH902618    KPU77871.1    SSX03816.1    SSX24181.1    GAKP01012505    GAKP01012503    JAC46449.1    AAS65047.1    AAN11930.1    KMY98762.1    KRG05964.1    KRK01564.1    KQS43735.1    KPU77870.1    JRES01000080    KNC34280.1    KA648242    AFP62871.1    AAF50207.2    EDV51252.1    KMY98763.1    CH480815    EDW40926.1    EDW93957.1    KQS43734.1    KMY98754.1    CCAG010003300    CCAG010003301    KRK01561.1    KMY98760.1    AAS65046.1    AAN11929.1    KMY98761.1   

Proteomes

UP000007151    UP000005204    UP000053240    UP000218220    UP000053268    UP000069940    + More
UP000008820    UP000075886    UP000075880    UP000007062    UP000030765    UP000242457    UP000053105    UP000008237    UP000000311    UP000036403    UP000076502    UP000078542    UP000005205    UP000009046    UP000001819    UP000000803    UP000215335    UP000053097    UP000268350    UP000008711    UP000075809    UP000008792    UP000279307    UP000192221    UP000002282    UP000092553    UP000078540    UP000009192    UP000007801    UP000037069    UP000095300    UP000001292    UP000192223    UP000092444    UP000092443    UP000092445   

PRIDE

H9IXU1    Q6NL70    M9PEQ4    Q7KUD6    Q8IQD4    Q7KUD7    + More
Q8IQD5   

Pfam

PF00955   HCO3_cotransp        + More
PF07565   Band_3_cyto

Interpro

IPR001717   Anion_exchange        + More
IPR018241   Anion_exchange_CS       
IPR003020   HCO3_transpt_euk       
IPR016152   PTrfase/Anion_transptr       
IPR013769   Band3_cytoplasmic_dom       
IPR011531   HCO3_transpt_C       

SUPFAM

SSF55804   SSF55804       

Gene 3D

3.40.930.10    

ProteinModelPortal

A0A2H1VVQ0   A0A2W1B1V1   A0A212EXJ6   H9IXU1   A0A194QL83   A0A2A4JK01   + More
A0A194PFC3   U5ESC0   A0A182GLN1   D4HM38   A0A2M4B9U9   A0A2M4B9V3   A0A2M4B9X8   A0A1Q3G5A2   A0A1Q3G568   Q17LT4   A0A2M4A0B9   A0A2M4A0I7   A0A2M4A0D6   A0A2M4CSP5   A0A2M3ZFN9   A0A2M3YY57   A0A182QDR8   A0A2M4CSK8   A0A182JC93   A0A1S4GRB6   A7UU18   A0A084WRM6   A0A2A3EHC5   A0A0M9A6U3   E2C057   E2AI20   A0A0J7L1F8   A0A154P8N0   A0A195BY69   E9IUS6   A0A336KLM7   A0A1Y1MZV6   A0A158NL67   E0W1T8   A0A0R3P866   Q8IQD6   A0A034VY23   A0A232F6S7   A0A026WYT9   A0A3B0K2B8   Q6NL70   A0A0J9RTY1   A0A0Q5U3S8   A0A0A1X8C7   A0A336KIP2   A0A151WHE6   A0A0Q9WIK9   A0A0R3P8P7   A0A3L8D7S5   A0A0K8WBJ0   A0A1W4U954   A0A0R1DWP5   M9PEQ4   A0A0M4EAF3   A0A0J9RSF3   A0A0R3P500   A0A195BH70   A0A0Q9XBQ8   A0A0Q9WUH0   A0A0Q5U4F4   A0A1W4U9Q8   A0A336M5M2   A0A0R1E201   A0A0P8XT17   A0A336KG24   A0A034VVH9   Q7KUD6   Q8IQD4   A0A0J9RSY0   A0A0Q9XBW9   A0A0R1DWV7   A0A0Q5UIN4   A0A0P8Y8V0   A0A1W4UL13   A0A0L0CPJ9   A0A1W4UL47   T1PHE0   Q9VT48   B3NGL6   A0A0J9RSL2   A0A1I8PAF1   B4HLA7   A0A1W4XTB6   B4PDW1   A0A0Q5UII5   A0A0J9RTX7   A0A1B0FJB2   A0A1A9YNN6   A0A0R1DX16   A0A0J9UID3   Q7KUD7   Q8IQD5   A0A0J9RSF9   A0A1A9Z321  

PDB

4YZF     E-value=8.31282e-174,     Score=1571

KEGG

101741181    no KO assigned | (RefSeq) anion exchange protein 3

GO

GO:0016021   GO:0005452   GO:0015701   GO:0005887   GO:0051453   GO:0006811   GO:0051452   GO:0005623   GO:0006820   GO:0016020   GO:0008509   GO:0005215   GO:0006810  

PANTHER

PTHR11453  

Subcellular location

Membrane  

Length:

1113

Number of predicted TMHs:

12

Exp number of AAs in TMHs:

260.90837

Exp number, first 60 AAs:

0

Total prob of N-in:

0.00012

outside

1  -  587

TMhelix

588  -  610

inside

611  -  622

TMhelix

623  -  645

outside

646  -  669

TMhelix

670  -  692

inside

693  -  704

TMhelix

705  -  727

outside

728  -  776

TMhelix

777  -  799

inside

800  -  811

TMhelix

812  -  834

outside

835  -  862

TMhelix

863  -  885

inside

886  -  905

TMhelix

906  -  928

outside

929  -  965

TMhelix

966  -  988

inside

989  -  992

TMhelix

993  -  1011

outside

1012  -  1037

TMhelix

1038  -  1055

inside

1056  -  1059

TMhelix

1060  -  1082

outside

1083  -  1113

 

 

Pi

1.24273

Theta

3.456986

Tajima's D

-1.971971

CLR

0.578383

CSRT

0.0109494525273736

Interpretation

Possibly Positive selection