| Gene | Sub Loc | Uniprot Sublocation | Topology | |
|---|---|---|---|---|
| KWMTBOMO00174 | Nuclear |
|
outside 1 - 802 |
|
| KWMTBOMO00175 | Nuclear |
|
outside 1 - 443 |
|
| KWMTBOMO00176 | PlasmaMembrane |
|
outside 1 - 31 TMhelix 32 - 54 inside 55 - 144 |
|
| KWMTBOMO00177 | Nuclear |
Membrane |
outside 1 - 23 TMhelix 24 - 46 inside 47 - 403 |
|
| KWMTBOMO00178 | Cytoplasmic |
|
outside 1 - 432 |
|
| KWMTBOMO00179 | Nuclear |
|
outside 1 - 726 |
|
| KWMTBOMO00180 | Nuclear |
|
outside 1 - 689 |
|
| KWMTBOMO00181 | Nuclear |
|
inside 1 - 241 TMhelix 242 - 261 outside 262 - 262 |
|
| KWMTBOMO00182 | Extracellular |
|
outside 1 - 300 |
|
| KWMTBOMO00182 | PlasmaMembrane |
|
outside 1 - 300 |
|
| KWMTBOMO00183 | Nuclear |
|
outside 1 - 540 |
|
| KWMTBOMO00184 | Cytoplasmic |
|
outside 1 - 216 |
|
| KWMTBOMO00185 | Nuclear |
|
outside 1 - 1458 |
|
| KWMTBOMO00186 | PlasmaMembrane |
Nucleus Proheparanase is secreted via vesicles of the Golgi. Interacts with cell membrane heparan sulfate proteoglycans (HSPGs). Endocytosed and accumulates in endosomes. Transferred to lysosomes where it is proteolytically cleaved to produce the active enzyme. Under certain stimuli, transferred to the cell surface. Associates with lipid rafts. Colocalizes with SDC1 in endosomal/lysosomal vesicles. Accumulates in perinuclear lysosomal vesicles. Heparin retains proheparanase in the extracellular medium (By similarity). referred by 1 publications |
inside 1 - 6 TMhelix 7 - 26 outside 27 - 515 |
|
| KWMTBOMO00187 | Extracellular |
Secreted |
outside 1 - 480 |
|
| KWMTBOMO00188 | Cytoplasmic |
Endoplasmic reticulum lumen |
outside 1 - 443 |
|
| KWMTBOMO00189 | Nuclear |
|
outside 1 - 1510 |
|
| KWMTBOMO00190 | Nuclear |
Endoplasmic reticulum-Golgi intermediate compartment membrane Detected at growth cones in thalamus neurons. Detected at growth cones in thalamus neurons (By similarity). PRRG4 prevents cell surface location and both colocalize in the Endoplasmic reticulum/Golgi adjacent to the cell nucleus (By similarity). referred by 13 publications |
outside 1 - 20376 |
|
| KWMTBOMO00191 | Nuclear |
Colocalizes with ball and mask in Z-lines of indirect flight muscle (PubMed:26251439). In the embryo, localizes across the muscles in a striped pattern positioned at the sites at which muscles are attached to the epidermis. In the larval body wall muscles, localizes to the Z line and is still present as a doublet at the muscle-epidermal attachment sites. During pupa development, progressively forms broad striations at the Z line which become more defined after the pupa eclosion. referred by 12 publications |
outside 1 - 2463 |
|
| KWMTBOMO00192 | Extracellular |
|
outside 1 - 152 |
|
| KWMTBOMO00192 | Nuclear |
|
outside 1 - 152 |
|
| KWMTBOMO00193 | Cytoplasmic |
Nucleus |
outside 1 - 111 |
|
| KWMTBOMO00193 | Mitochondrial |
Nucleus |
outside 1 - 111 |
|
| KWMTBOMO00193 | Nuclear |
Nucleus |
outside 1 - 111 |
|
| KWMTBOMO00194 | Extracellular |
|
outside 1 - 135 |
|